Atazanavir CAS 198904-31-3 Purity ≥99.0% API Factory Anti-HIV-1 Protease Inhibitor

Inkcazelo emfutshane:

Igama leMichiza: Atazanavir

CAS: 198904-31-3

Imbonakalo: Umgubo oMhlophe

Ubunyulu: ≥99.0%

HIV-1 Protease Inhibitor

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ukubonelela ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leMichiza: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
Umgangatho ophezulu we-API, iMveliso yoRhwebo

Iipropati zeMichiza:

Igama leMchiza	Atazanavir
Izithethantonye	BMS-232632
Inombolo yeCAS	198904-31-3
Inombolo yeCAT	RF-API70
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	I-C38H52N6O7
Ubunzima beMolekyuli	704.86
Indawo yokunyibilika	207.0 ~ 209.0℃
Ukunyibilika	Inyibilika kwi-DMSO;Ayinyibilikiyo emanzini
Ugcino Lwexesha elide	Gcina Ixesha elide kwi -20 ℃
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe
Ifom	Isiseko sasimahla
Ilahleko ekomisweni	≤0.50%
Intsalela kwi-Ignition	≤0.20%
Iintsimbi ezinzima	≤20ppm
Ukungcola A	≤0.10%
Ukungcola B	≤0.10%
Ukungacoceki Okukodwa	≤0.20%
Ukungcola ngokupheleleyo	≤1.0%
Indlela yokuhlanjululwa / yoHlalutya	≥99.0% (HPLC)
pH	5.0~8.0
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	HIV-1 Protease Inhibitor Anti-HIV

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, Igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Atazanavir (CAS 198904-31-3) yi-antiretroviral, inoveli kunye neyeza elinamandla le-azapeptide yeklasi ye-protease inhibitor (PI).Ithengiswa phantsi kwegama lezorhwebo elithi Reyataz.Njengezinye ii-antiretrovirals, isetyenziselwa ukunyanga usulelo lwe-human immunodeficiency virus type 1 (HIV-1) protease enzyme kunye ne-inhibition constant Ki ye-66 nmol/L kwaye ikwathintela ukuphindaphindwa kwentsholongwane ye-HIV-1 kunye ne-50% yoxinaniso olusebenzayo EC50 ukusuka 2.6 ukuya ku-5.3 nmol/L.I-Atazanavir ibophelela kwi-HIV-1 protease inqanda ukuqhekeka kwe-gag kunye ne-gag-pol polyprotein, okukhokelela ekwenziweni kwee-virion ezingekavuthwa kwiiseli ezosulelwe yi-HIV-1.I-Atazanavir inokwakheka kweekhemikhali ezilinganayo ze-C-2 kunye namandla e-antiretroviral ngokubanzi kwiintlobo ezahlukeneyo ze-HIV xa kuthelekiswa nezinye ii-protease inhibitors, kubandakanywa i-Indinavir, i-Nelfinavir, i-Ritonavir, i-Saquinavir kunye ne-Amprenavir.I-Atazanavir yohlulwe kwezinye ii-PIs kuba inokunikwa kanye ngemini kwaye ineziphumo ezincinci kwiprofayili yelipid yesigulane.Njengezinye ii-protease inhibitors, isetyenziswa kuphela ngokudityaniswa namanye amayeza e-HIV.I-Atazanavir yinoveli ye-azapeptide HIV protease inhibitor.I-Antiviral.Ithathwa ngomlomo kanye ngosuku.