Azilsartan CAS 147403-03-0 Ubunyulu > 99.5% (HPLC) API Factory
Ubonelelo lwabavelisi, ubunyulu obuphezulu, iMveliso yoRhwebo
Igama leMchiza | Azilsartan |
Izithethantonye | I-2-Ethoxy-1-[[2'- (4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl]methyl]benzimidazole-7-Carboxylic Acid |
Inombolo yeCAS | 147403-03-0 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C25H20N4O5 |
Ubunzima beMolekyuli | 456.46 |
Indawo yokunyibilika | 188℃ (ngoDisemba) |
Ukuxinana | 1.42 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe |
Ukuchongwa | Ingqinelana noMgangatho weReference |
Ukunyibilika | Ayinyibiliki ngokupheleleyo emanzini, iNyibilika kancinane kwi-Ethanol |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
Ilahleko ekomisweni | <0.50% |
Intsalela kwi-Ignition | <0.20% |
Iintsimbi ezinzima | <10ppm |
Izinto ezinxulumeneyo | |
Ukungcola A | <0.15% |
Ukungcola B | <0.10% |
Ukungcola C | <0.10% |
Okunye Okungaziwayo Okukungacoceki Okukhulu Okukodwa | <0.10% |
Ukungcola ngokupheleleyo | <0.50% |
Izinyibilikisi ezishiyekileyo | |
Dichloromethane | <0.06% |
I-acetone | <0.50% |
I-Ethyl Acetate | <0.50% |
IMethanol | <0.30% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-Azilsartan (i-CAS: i-147403-03-0) i-angiotensin II receptor antagonist drug phantsi kophuhliso lonyango lwe-hypertension, esetyenziswa kakhulu kunyango lwe-hypertension.Ikwayiyo yodwa i-angiotensin II receptor antagonist (iklasi yesartan) iyeza elikwinqanaba eliphezulu leklinikhi okwangoku.I-Azilsartan kunye neChlorthalidone indibaniselwano isetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi).I-Azilsartan yi-angiotensin II receptor blocker (ARB).Isebenza ngokuthintela into ethile emzimbeni eyenza ukuba imithambo yegazi iqine.Ngenxa yoko, i-azilsartan ikhulula imithambo yegazi.Oku kwehlisa uxinzelelo lwegazi kwaye kwandisa ukunikezelwa kwegazi kunye neoksijini entliziyweni.I-Azilsartan yavunywa kwaye yaqaliswa eJapan kunyango lwe-arterial hypertension ngoMeyi 2012. I-Azilsartan, ethengiswa phantsi kwegama lezorhwebo elithi Azilva.