I-Betulin CAS 473-98-3 Ucoceko > 99.0% (HPLC) Isicatshulwa sesityalo
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Betulin (i-CAS: 473-98-3) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga iBetulin,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Betulin |
| Izithethantonye | iBetulinol;Utywala be-Betulinic;iBetula Camphor;I-Birch Bark Extract;iBetulol;iTrochol;I-Lup-20 (29)-ene-3β, i-28-diol;(3β)-Lup-20 (29)-ene-3,28-diol |
| Ubume beStokhwe | Kwi-Stock, Kwenziwa uRhwebo |
| Inombolo yeCAS | 473-98-3 |
| Ifomula yeemolekyuli | C30H50O2 |
| Ubunzima beMolekyuli | 442.73 g/mol |
| Indawo yokunyibilika | 251.0 ~ 257.0℃ |
| Ukuxinana | 1.017g/cm3 |
| Ujikelezo oluKhethekileyo [a]20/D | +17.0 ° ukuya +21.0 ° (C=2 kwiPyridine) |
| Uzinzo | Hygroscopic |
| Ugcino Temp. | Indawo epholileyo neyomileyo (2~8℃) |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Udidi | Izicatshulwa zezityalo |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Mhlophe ukuya kwi-Off-White Powder | Umgubo oMhlophe |
| Betulin Ubunyulu | >98.0% (HPLC) | 99.15% |
| Indawo yokunyibilika | 251.0 ~ 257.0℃ | Iyahambelana |
| Ilahleko ekomisweni | <2.00% (2g/105℃/5hrs) | 0.13% |
| Uthuthu | <0.50% (2g/600℃/5hrs) | 0.10% |
| Unizi lolwapho kuyiwa khona | 0.25~0.45 g/ml | Iyahambelana |
| Ubungakanani beNcam | 98% Dlula i-80 Mesh | Iyahambelana |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| IArsenic (As) | ≤1ppm | <1ppm |
| Intsalela yokunyibilika | ≤1000ppm | Iyahambelana |
| Iimvavanyo zeMicrobiological | ||
| Ukubalwa kwePleti iyonke | ≤1000CFU/g | Iyahambelana |
| Igwele kunye noMngundo | ≤100CFU/g | Iyahambelana |
| Escherichia Coli | Ibi | Ibi |
| I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| Ukunyibilika kwiPyridine 50mg/ml | Mthubi ukuya kuBrown Ngokucacileyo ukuya kwiHazy kaNcinci | Dlula |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engenamoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma kunye nobushushu obuphezulu.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iikhowudi zoMngcipheko
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
I-R20/21/22 - Iyingozi ngokuphefumla, xa udibana nolusu naxa uginyiwe.
R68/20/21/22 -
R68 - Umngcipheko onokubakho weziphumo ezingajikiyo
Inkcazelo yoKhuseleko
S36/37 -Nxiba iimpahla ezifanelekileyo zokukhusela kunye neeglavu.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
WGK eJamani 3
RTECS OK5755000
Ikhowudi yeHS 2906199090
I-Betulin (i-CAS: 473-98-3) isicatshulwa kwi-bark yomthi omhlophe we-birch, owaziwayo ukususela ngekhulu le-18 kwaye ichazwa ngamachiza.I-Betulin yafunyanwa ngusokhemisti waseJamani-Russian uJohann Tobias Lowitz.Wayeyinzululwazi yokuqala ukufunda kunye nokubonakalisa i-betulin, kwaye ekwenzeni kwakhe yaba ngomnye wabokuqala ukwahlula isithako sesityalo esisebenzayo.I-Betulin yinxalenye yesityalo esisulungekileyo esenza ukuba ixolo le birch libe nombala walo omhlophe.I-Betulin ikhusela imithi ye-birch kwimiphumo yokusingqongileyo, njengamaqondo okushisa agqithisileyo, ukuhlaselwa kwezinambuzane kunye nemitha yelanga.
IBetulin ngumgubo omhlophe oyikristale, unyibilika etywaleni, kwiklorofomu nakwibenzene, unyibilika kancinane emanzini abandayo, i-petroleum ether.
Imiphumo ye-Physiological ye-betulin
1. I-Betulin kunye nezinto eziphuma kuyo zibonise amandla amakhulu njengee-arhente zebhayoloji kwi-HIV kunye nonyango lomhlaza.Basebenza ngokuphazamisana nezigaba zamva zomjikelo wobomi bentsholongwane kwaye zinxulumene nokungena kwentsholongwane kunye nokukhula kunye nokuvuthwa.
2. Iziyobisi ezisebenzayo ezichasene nethumba, ezibangela ngokuthe ngqo ezinye iintlobo zeeseli zethumba ukuba ziqalise iinkqubo ezizitshabalalisayo ze-apoptosis, kwaye zinokucothisa ukukhula kweentlobo ezininzi zeeseli zethumba.
3. I-Betulin inokunciphisa ukutyeba okubangelwa kukutya, ukunciphisa umxholo we-lipid kwi-serum kunye nezicubu, kunye nokuphucula i-sulin k sensitivity.
4. Baneempawu ezichasene ne-anti-inflammatory kwiindawo eziphezulu, kunye neempawu zabo ezichasayo ngokuyinhloko ngenxa yokuthintela iindlela ezingezona ze-neural gene.
5. I-Betulin inokuthintela ukuvuthwa kwe-sterol regulatory element-binding proteins (SBERPs) kwi-vivo, ngaloo ndlela inciphisa i-biosynthesis ye-cholesterol kunye ne-fatty acids.
6. Ukongezelela, i-Betulin ine-anti-inflammatory, anti-viral, inhibiting protein dissolution kwi-fiber yeenwele, ukuphucula ukukhanya kweenwele ezonakalisiweyo, kunye nokukhuthaza ukukhula kweenwele.I-Betulin ingasetyenziselwa ukutya, izimonyo kunye namashishini amayeza.
Umzi mveliso wamayeza:
I-Betulin isetyenziswa kakhulu njengendawo yoxubo-mayeza, kwaye i-Betulin kunye nezinto eziphuma kuyo njengee-arhente zebhayoloji zibonise amandla amakhulu kunyango lwe-HIV kunye nomhlaza.Ngelo xesha, isetyenziselwa i-antitussive kunye ne-expectorant, unyango lwe-rhinitis ye-allergic, ukulala, ukudandatheka, njl.
Ishishini lokutya:
Kukho izifundo eziyisebenzisayo njengesigcinakaliso kwiimveliso zenyama.
Ishishini lezithambiso:
Impembelelo yokuthintela ye-Betulin kumsebenzi we-collagenase kunye nokwanda kweeseli zesikhumba kubonisa ukuba inefuthe elinamandla lokulwa nokuguga kwaye ingasetyenziselwa ukumisa ulusu, ukugulisa ulusu, kunye nokukhusela ulusu oluqhekekile.Kwakhona kuncedo olulungileyo lokungena ngaphandle.
Okwangoku i-Betulin ifunyenwe ngokuyinhloko ngokutsalwa ngokuthe ngqo, kwaye ngokuyininzi nge-solvent reflux extraction kunye ne-recrystallization purification Ngokukodwa: 1. Khipha i-betulin kwisisombululo se-ethanol.Emva kokufudumeza i-reflux malunga ne-5h, i-extract i-vacuum distillized kwaye iphinda ihlaziywe nge-ethanol ngamaxesha angama-2 ukuya kwe-3 nge-ethanol ukufumana imveliso engcolileyo ye-betulin.2. Imveliso ekrwada yaphinda yahlaziywa kwi-methanol / chloroform (1: 1) (yonke i-80g yemveliso ekrwada ifuna i-300mL ye-methanol / isisombululo se-chloroform) .Umxube uvumelekile ukuba ume ubusuku bonke kwaye emva koko ukufunxa kuhluzwe ukufumana i-betulin emhlophe njengenaliti.3. Unyango lwe-Ultrasonic lwe-20min xa i-refluxing iqhutyelwa, kwaye isivuno sokukhutshwa kunye nokuhlanjululwa kwemveliso ye-betulin kunokuphuculwa ngokutshabalalisa umbutho we-bark.4. Ezona meko zilungileyo zokutsalwa kwe-CO2 fluid zimi ngolu hlobo lulandelayo: ubungakanani be-modifier yi-115mL/(g birch bark powder);uxinzelelo lokutsalwa yi-20MPa;iqondo lobushushu lokutsalwa laliyi-55℃;ulwelo lwe-CO2 izinga lokuhamba libe yi-10kg/h.
