Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Advanced Prostate Cancer Umfanekiso ofakiweyo

I-Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Advanced Prostate Cancer

Inkcazelo emfutshane:

Igama: Bicalutamide

CAS: 90357-06-5

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Uvavanyo: 98.0% ~ 102.0%

I-Bicalutamide kunyango lwe-Advanced Prostate Cancer

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama: Bicalutamide
CAS: 90357-06-5
I-Bicalutamide kunyango lwe-Advanced Prostate Cancer
Umgangatho ophezulu we-API, iMveliso yoRhwebo

Iipropati zeMichiza:

Igama	I-Bicalutamide
Izithethantonye	N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide
Inombolo yeCAS	90357-06-5
Inombolo yeCAT	RF-API76
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	I-C18H14F4N2O4S
Ubunzima beMolekyuli	430.37
Ubushushu boGcino	2-8℃
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe oMhlophe wePowder
Isazisi A	I-IR: I-Spectrum yesampuli ihambelana naleyo yomgangatho wereferensi
Isazisi B	I-HPLC: Ixesha lokugcinwa kwencopho enkulu yesisombululo sesampulu ihambelana nesisombululo esiqhelekileyo
Isazisi C	Ukuchongwa kweFluoride ephilayo
Ukunyibilika	Inyibilika ngokukhululekileyo kwi-acetone kunye neTetrahydrofuran, iNyibilika kancinane kwi-Ethyl acetate
Indawo yokunyibilika	191.0 ~ 195.0℃
Isiqulatho samanzi (nge-KF)	≤0.20%
Umxholo weFluoride	15.9%~18.5%
Ilahleko ekomisweni	≤0.50%
Intsalela kwi-Ignition	≤0.10%
Iintsimbi ezinzima	≤10ppm
Izinyibilikisi ezishiyekileyo
Tetrahydrofuran	≤0.072%
Toluene	≤0.089%
N-Hexane	≤0.029%
I-acetone	≤0.50%
I-Ethyl Acetate	≤0.50%
Izinto ezinxulumeneyo
N, N'-Dimethyl Acetamide	≤0.109%
Bicalutamide Aminobenzonitrile	≤0.10%
I-Bicalutamide eNxulumene nayo iCompound A Isomer A	≤0.10%
I-Bicalutamide eNxulumene nayo iCompound A Isomer B	≤0.10%
Desfluoro Bicalutamide	≤0.20%
I-2-Fluoro Bicalutamide	≤0.20%
I-Deoxy Bicalutamide	≤0.20%
I-Bicalutamide Sulfidi	≤0.10%
Nakuphi na Ukungcola Okungachazwanga	≤0.10%
Ukungcola ngokupheleleyo	≤0.50%
Ubungakanani beNcam	90%<10um;50%<5um
Isivavanyi	98.0% ~ 102.0% (kwisiseko esomileyo)
Iimvavanyo zeMicrobiological
Ubalo oluSebenzayo lweAerobic iyonke	≤500CFU/g
Igwele kunye nokungunda	≤50CFU/g
Beka ubomi kwishelufa	Iinyanga ezingama-24
Umgangatho woVavanyo	uMgangatho woShishino;Umgangatho we-USP
Ukusetyenziswa	I-API, kunyango lwe-Advanced Prostate Cancer

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Bicalutamide (i-CAS: i-90357-06-5) ngumchasi we-androgen ongeyena-steroidal, okhuphisana ne-androgen receptor kunye ne-androgen, ibhloko i-cell cell uptake ye-androgen, kwaye inqanda ukubopha i-androgens kwinqanaba elijoliswe kuyo.Ibophelela kunye ne-androgen receptor eyenza i-receptor complex, engena kwi-nucleus kwaye idibaniswe ne-nucleoprotein, ngenxa yoko inqanda ukukhula kweeseli ze-tumor.Isenokuba lichiza lokuqala lonyango lokuthomalalisa umhlaza wedlala lesinyi.I-Bicalutamide yaphehlelelwa e-United Kingdom, imarike yayo yokuqala yehlabathi, kunyango lomhlaza wedlala lesinyi ngokudityaniswa ne-analog ye-LHRH okanye ukuthenwa ngotyando.I-non-steroidal, i-peripherally selective antiandrogen, i-bicalutamide inqanda isenzo se-dihydrotestosterone kunye ne-testosterone kwiindawo ezijoliswe kuzo ngokubophelela okukhuphisanayo kwi-cytosolic androgen receptor.Kuxelwe ukuba kunyanyezelwe kakuhle ngaphandle kweziphumo ezibi zentliziyo kunye ne-metabolic ngenxa yenzuzo yokuswela nawuphi na umsebenzi we-steroid.Ukusebenza kwe-bicalutamide njenge-monotherapy kubonakaliswe kwiklinikhi.Amazinga okuphendula athembisayo nawo axelwe ekunyangeni i-colorectal, ibele, i-pancreas kunye nomhlaza wemiphunga weseli ongeyonxalenye encinci.