I-Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Biotin (i-Vitamin H) (i-CAS: 58-85-5) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga i-Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Igama leMchiza | I-Biotin |
| Izithethantonye | D-Biotin;D(+)-Biotin;iVithamini H;I-Bios II;ivithamini B7;iCoenzyme R;I-Biotinum |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 58-85-5 |
| Ifomula yeemolekyuli | I-C10H16N2O3S |
| Ubunzima beMolekyuli | 244.31 g/mol |
| Indawo yokunyibilika | 231.0~233.0℃(lit.) |
| Ukunyibilika kwamanzi | Inyibilika kancinane emanzini |
| Ukunyibilika kwi-0.1mol/L NaOH | Phantse Ukungafihli |
| Ukunyibilika | Inyibilika kancinane kuTywala, iChloroform, iEtere |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe | Umgubo weCrystalline oMhlophe |
| Ukuchongwa | Umdlalo we-IR kunye ne-Reference IR Spectrum | Iyahambelana |
| Ixesha lokugcinwa | Ifanele ifane naleyo yeRS | Iyahambelana |
| Ujikelezo oluKhethekileyo [a]20/D | +89.0 ° ukuya +93.0 ° (C=2 ku-0.1 M NaOH) | + 90,8 ° |
| Isivavanyi | 97.5~100.5% | 99.8% |
| Ilahleko ekomisweni | <0.50% | 0.05% |
| Izinto ezinxulumeneyo | ||
| Ukungacoceki komntu | <1.00% | Iyahambelana |
| Ukungcola ngokupheleleyo | <2.00% | Iyahambelana |
| Izinyibilikisi ezishiyekileyo | ||
| Benzeni | <2ppm | <0.2ppm |
| Toluene | <100ppm | <10ppm |
| I-DMSO | <5000ppm | <500ppm |
| Uvavanyo lweMicrobial | ||
| Ubalo oluSebenzayo lweAerobic iyonke | ≤1000cfu/g | Iyahambelana |
| I-Yeasts iyonke kunye ne-Molds Bala | ≤100cfu/g | Iyahambelana |
| Escherichia Coli | ND/1g | / |
| Staphylococcus Aureus | ND/1g | / |
| Pseudomonas Aeruginosa | ND/1g | / |
| Enterobacteria | ND/1g | / |
| Iintlobo zeSalmonella | ND/10g | / |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
INGCACISO Uhlalutyo I-Biotin iqulethe i-NLT 97.5% kunye ne-NMT 100.5% ye-Biotin (C10H16N2O3S).
UKUCHAZA
• A. UKUFUNWA KWE-IFRARED <197K>
B. Ihlangabezana neemfuno kwiimvavanyo eziKhethekileyo zokujikeleza kwe-Optical Rotation, i-Specific Rotation <781S>.
C. Ixesha lokugcinwa kwencopho enkulu yeSampuli yesisombululo ihambelana nesisombululo soMgangatho, njengoko kufunyenwe kwi-Assay.
UVAVANYO
• INKQUBO
Isicombululo se-buffer: Dibanisa i-1 g ye-sodium perchlorate monohydrate kwi-500 mL yamanzi, yongeza i-1 mL ye-phosphoric acid, kwaye udibanise ngamanzi kwi-1000 mL.
Isigaba seselula: isisombululo se-Acetonitrile kunye ne-Buffer (8.5: 91.5)
Diluent: Iacetonitrile namanzi (1:4)
Isisombululo esisemgangathweni: 0.1 mg / mL ye-USP Biotin RS kwi-Diluent.Sonicate ukuba kuyimfuneko ukunyibilika
Isisombululo sesampuli: 0.1 mg / mL ye-Biotin kwi-Diluent.Sonicate ukuba kuyimfuneko ukunyibilika.
Inkqubo yeChromatographic
(Jonga iChromatography <621>, Ukufaneleka kweNkqubo.)
Indlela: LC
Umtshina: UV 200 nm
Ikholomu: 4.6-mm × 15-cm;3-µm ukupakisha i-L7
Izinga lokuhamba: 1.2 mL / min
Ubungakanani betofu: 50 µL
Ukufaneleka kwenkqubo
Isampulu: Isisombululo esisemgangathweni
Iimfuno zokufaneleka
Umba wokutsala: NMT 1.5
Ukutenxa komgangatho ozalanayo: NMT 2.0% yokuphinda-phinda iinaliti
Uhlalutyo
Iisampulu: Isisombululo esisemgangathweni kunye nesisombululo seSampuli
Bala ipesenti yeBiotin (C10H16N2O3S) kwinxalenye yeBiotin ethathiweyo:
Isiphumo = (rU/rS) × (CS/CU) × 100
rU = impendulo ephezulu evela kwiSampuli yesisombululo
rS = impendulo ephezulu evela kwisisombululo esiPhakathi
CS = ukuxinwa kwe-USP Biotin RS kwisisombululo esiPhakathi (mg/mL)
I-CU = i-concentration ye-Biotin kwi-Sample solution (mg/mL)
Indlela yokwamkela: 97.5% -100.5%
UBUNGCOLA
• IINDLELA EZINXULUMENEYO
Isisombululo se-Buffer, isigaba se-Mobile, i-Diluent, isisombululo esiPhakathi, isisombululo seSampulu, inkqubo yeChromatographic kunye nokufaneleka kweNkqubo: Qhubeka njengoko uqondiswe kwi-Assay.
Uhlalutyo
Isampulu: Isampuli yesisombululo
Ukulinganisa iimpendulo eziphakamileyo kwiSampuli yesisombululo.
Bala ipesenti yokungahlambuluki ngakunye kwisahlulo seBiotin esithathiweyo:
Isiphumo = (rU/rT) × 100
I-rU = impendulo ephezulu yokungahlambuluki nganye kwisisombululo seSampuli
rT = isimbuku seempendulo zencopho yazo zonke iincopho ezivela kwiSampuli yesisombululo
Iinqobo zokwamkelwa
Ukungacoceki komntu: NMT 1.0%
Ubumdaka bubonke: NMT 2.0%
IIMVAVANYO EZITHILE
• UKUJONGISWA KOMBONISO, ukujikeleziswa okuthe ngqo <781S>
Isisombululo sesampuli: 20 mg / mL kwi-0.1 N sodium hydroxide
Indlela yokwamkela: +89 ° ukuya +93 °
IIMFUNO EZONGEZELELWEYO
• UKUPAKISHWA NOKUGCINA: Gcina kwizikhongozeli eziqinileyo.
• IMIGANGATHO YE-USP REFERENCE <11>
USP Biotin RS
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iimpawu zeHazard Xn - Ziyingozi
Iikhowudi zoMngcipheko R20/21/22 - Zinobungozi ngokuphefumla, xa udibana nolusu kwaye xa uginyiwe.
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
Inkcazo yoKhuseleko S24/25 -Kuphephe ukudibana nolusu namehlo.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
WGK eJamani 1
RTECS XJ9088200
FLUKA BRAND F IIKHOWUDI 8
TSCA Ewe
Ikhowudi yeHS 2936290000
Ubutyhefu LD50 ngomlomo kuMvundla: > 2000 mg/kg
I-Biotin (i-Vitamin H; i-Vitamin B7) (i-CAS: 58-85-5)
I-Biotin yivithamini enyibilikayo emanzini kwiifom ezisibhozo, i-biotin.Yi-coenzyme - okanye i-enzayimu encedisayo - esetyenziswa kwiimpendulo ezininzi ze-metabolic emzimbeni.I-Dchemicalbook-biotin ibandakanyeka kwi-lipid kunye ne-protein metabolism, inceda ukuguqula ukutya kwi-glucose, umzimba ongayisebenzisa njengamandla.Kwakhona kubalulekile ukugcina ulusu, iinwele kunye nenwebu.
Njengesongezo sokutya, iBiotin isetyenziswa ikakhulu kwiinkukhu kunye nokutya kwehagu.Ngokuqhelekileyo i-premix mass fraction yi-1% -2%.
I-Biotin yongezelela isondlo.Ngokwemigaqo yaseTshayina GB2760-90, inokusetyenziswa njengeshishini lokutya njengoncedo lokulungisa.Inemisebenzi ye-physiological ukukhusela izifo zesikhumba kunye nokukhuthaza i-lipid metabolism kunye nokunye.
I-Biotin yi-carboxylase coenzyme, ebandakanyeka kwiimpendulo ezininzi ze-carboxylation, kwaye i-coenzyme ebalulekileyo kwi-metabolism yeswekile, iprotheni kunye namafutha.
I-Biotin isetyenziselwa ukomeleza ukutya.I-Biotin isetyenziselwa ukutya kweentsana kunye nenani le-0.1 ~ 0.4mg / kg, kulwelo lokusela 0.02 ~ 0.08mg / kg.
I-Biotin ingasetyenziselwa ukubhala iiprotheni, ii-antigens, ii-antibodies, i-nucleic acids (i-DNA, i-RNA) njalo njalo.
I-Biotin inokwenza iinwele zinwebe, zithintele ukulahleka kweenwele kwangoko kwaye ziphucule ukuxhathisa kwendalo kolusu.Ikwanokusebenza okuthile kokuchasana nemibimbi.Inokuphucula ukwakheka kombutho jikelele eluswini, yandise ukuguquguquka kwezikhonkwane, iphucule ubume bezikhonkwane ezibhityileyo kwaye yenze izikhonkwane zibe zintle ngakumbi kwaye zigudileyo ngokukhuthaza ukuhlanganiswa kwelipids.
Ukungabikho kwe-biotin kunokubangela i-dermatitis, i-atrophic glossitis, i-hyperesthesia, i-myalgia, i-malaise, i-anorexia, kunye ne-anemia ephakathi, kwaye iimpawu ziyanyamalala kunye ne-biotin supplementation.Isiphumo saso esixhaphakileyo kukuqhambuka kwe-cystic acne.Kodwa kubantu abaninzi, ukusetyenziswa ngokugqithiseleyo kwale vithamini akubangeli umphumo ombi.Nangona kunjalo, abafazi abakhulelweyo akufanele bathathe i-biotin ngenxa yomngcipheko wokuphuphuma kwesisu.
Ubuthi be-Biotin bubonakala buphantsi, unyango lwe-seborrheic dermatitis kunye namanani aphezulu e-Biotin aluzange luveze iprotheni engaqhelekanga yemetabolism okanye iimpazamo zemfuza kunye nezinye izitenxo ze-metabolic.Uvavanyo lwezilwanyana lubonise ubutyhefu obuncinci beBiotin.
