I-Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4 Ucoceko >99.5% EE >99.5%

Inkcazelo emfutshane:

Igama: Boc-3-Hydroxy-1-Adamantyl-D-Glycine

CAS: 361442-00-4

Ubunyulu: >99.5% (GC) EE: >99.5%

Imbonakalo: Umgubo weCrystalline oMhlophe okanye oMhlophe

I-API ephakathi (CAS: 361442-04-8)

E-Mail: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

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Iithegi zeMveliso

Inkcazo:

Ruifu Chemical Supply Related Intermediates
I-CAS 361442-04-8
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(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
I-Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
I-2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7

Iipropati zeMichiza:

Igama leMchiza	I-Boc-3-Hydroxy-1-Adamantyl-D-Glycine
Izithethantonye	(2S)-2-((tert-Butoxycarbonyl)amino)-2-(3-Hydroxyadamantan-1-yl)acetic Acid
Inombolo yeCAS	361442-00-4
Inombolo yeCAT	RF-PI1989
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C17H27NO5
Ubunzima beMolekyuli	325.40
Indawo yokubilisa	497.3±20.0℃
Ukuxinana	1.296
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo weCrystalline oMhlophe okanye oMhlophe
Amanzi (KF)	<0.50%
Ilahleko ekomisweni	<1.00%
Intsalela kwi-Ignition	<0.50%
Ukungacoceki Okukodwa	<0.50%
Ukungcola ngokupheleleyo	<0.50%
EE	>99.5%
Ubunyulu	>99.5%
I-Infrared Spectrum	Iyahambelana neSakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	AbaPhakathi bamayeza

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

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Isicelo:

I-Boc-3-Hydroxy-1-Adamantyl-D-Glycine (CAS: 361442-00-4) iphakathi kwe-API (CAS: 361442-04-8).API (CAS: 361442-04-8)sisithinteli esinamandla nesikhethayo sokubuyisela i-dipeptidyl peptidase-4, ephuhliswa kunyango lwe-2 seswekile.Ifunxwa ngokukhawuleza emva kokulawulwa komlomo kwaye ineprofayili ye-pharmacokinetic ehambelana ne-dosing kanye ngosuku.Yi-dipeptidyl peptidase-4 (DPP-4) inhibitor antidiabetic kunyango lwe-2 yeswekile.I-DPP-4 inhibitors yiklasi yeekhompawundi ezisebenza ngokuchaphazela isenzo sehomoni yendalo emzimbeni obizwa ngokuba yi-incretins.Yonaisetyenziswa kunye nokutya kunye nokuzivocavoca ukuphucula ulawulo lweswekile yegazi kubantu abadala abane-type 2 yeswekile mellitus.Asiyonto yokunyanga isifo seswekile se-1.Yonangamanye amaxesha isetyenziswa kunye namanye amayeza eswekile.Ifikelelwe yintsebenziswano ye-AstraZeneca kunye ne-Bristol-Myers Squibb Inkampani kwaye ingeye-DPP-IV inhibitor.