Brimonidine Tartrate CAS 70359-46-5 Assay 99.0% ~ 101.0%

Inkcazelo emfutshane:

Igama leKhemikhali: Brimonidine Tartrate

CAS: 70359-46-5

Uvavanyo: 99.0% ~ 101.0% (kwisiseko esomileyo)

Umgubo oMhlophe okanye oMthubi kancinane okanye omdaka kancinane

I-Agonist eKhethekileyo ye-α-Adrenergic Receptor

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

70359-46-5 - Inkcazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili weBrimonidine Tartrate (CAS: 70359-46-5) kunye nomgangatho ophezulu.Ukukhetha i-α2-adrenergic receptor agonist, ichiza elisetyenziselwa ukunyanga i-glaucoma evulekile okanye i-ocular hypertension.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iBrimonidine Tartrate,Please contact: alvin@ruifuchem.com

70359-46-5 - Iipropati zeMichiza:

Igama leMchiza I-Brimonidine Tartrate
Izithethantonye I-Brimonidine L-Tartrate;UK 14304 Tartrate;I-AGN190342 Tartrate;I-5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl) i-quinoxalin-6-Amine Tartrate;I-5-Bromo-N- (4,5-Dihydro-1H-Imidazol-2-yl)-6-Quinoxalinamine Tartrate;5-Bromo-N-(4,5-Dihydro-1H-Imidazol-2-yl)quinoxalin-6-Amine (2R,3R)-2,3-Dihydroxysuccinate
Ubume beStokhwe Kwi-Stock, iMveliso yoRhwebo
Inombolo yeCAS 70359-46-5
Ifomula yeemolekyuli C11H10BrN5·C4H6O6
Ubunzima beMolekyuli 442.23 g/mol
Indawo yokunyibilika 207.0~208.0℃(Disemba)
Inovakalelo Ukungeva kuMoya, Ubushushu abuva
I-COA kunye ne-MSDS Iyafumaneka
Imvelaphi Shanghai, China
Beka ubomi kwishelufa Iinyanga ezingama-24 ukuba zigcinwe ngokufanelekileyo
Udidi I-API (Isithako soXwebhu esiSebenzayo)
Uphawu Ruifu Chemical

70359-46-5 - Iinkcukacha:

Izinto Iinkcukacha Iziphumo
Imbonakalo Mhlophe okanye Mthubi Kancinane okanye
Kancinci umgubo omdaka
Iyahambelana
Isazisi A Ujikelezo oluKhethekileyo lwe-Optical Iyahambelana
Isazisi B I-Infrared Absorption Spectrophotometry Iyahambelana
Ukunyibilika Inyibilika emanzini, ayinyibiliki kwi-ethanol ene-anhydrous nakwitoluene Iyahambelana
Ujikelezo oluKhethekileyo lwe-Optical +9.0 ° ~ +10.5 ° + 9,6 °
Ilahleko ekomisweni ≤0.50% 0.20%
Uthuthu lweSulfated ≤0.20% 0.07%
Iintsimbi ezinzima ≤20ppm <20ppm
Izinto ezinxulumeneyo    
Ukungcola Okuchaziweyo    
N-(imidazolidin2ylidene)quinoxalin-6-amine ≤0.10% Iyahambelana
I-5-bromoqulinoxalin-6-amine ≤0.10% Iyahambelana
I-Quinoxalin-6-amine ≤0.10% Iyahambelana
1-(5-bromoquinoxalin-6-yl) thiourea ≤0.10% Iyahambelana
I-2-(5-bromoquinoxalin-6-yl) i-guanidine ≤0.10% Iyahambelana
5-bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine ≤0.10% Iyahambelana
1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl) urea ≤0.10% Iyahambelana
Ukungcola Okungachazwanga ≤0.10% Iyahambelana
Iyonke ≤0.20% 0.12%
Isivavanyi 99.0%~101.0%(kwisiseko esomileyo) 99.8%
Ukuqukumbela Le mveliso ngokuhlola ihambelana neBP2015 Standard

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Kuphephe ukuchanabeka kwilanga elithe ngqo, ukufuma kunye nobushushu obugqithisileyo.
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Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

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Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.

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MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.

Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.

Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

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70359-46-5 - Ukhuseleko kunye neMimiselo:

IiNgxelo zeNgozi H301: Ityhefu xa iginyiwe.
IiNkcazo zokuQaphela
I-P501: Lahla iziqulatho/isikhongozeli kwiziko elivunyiweyo lokulahla inkunkuma.
P270: Ungatyi, ungaseli okanye utshaye xa usebenzisa le mveliso.
P264: Hlamba ulusu ngononophelo emva kokuphatha.
I-P301 + P310 + P330: UKUBA IYAGINWA: Ngoko nangoko fowunela i-POISON CENTER/ugqirha.Hlamba umlomo.
P405: Ivenkile itshixiwe.
Imithetho eNxulumeneyo:
Ulwazi lwezoThutho:
Inombolo ye-UN (DOT-AIR) UN2811
Udidi (DOT-AIR) 6.1
IQela lokuPakisha (TCI-A) III
Inombolo yeHS 2933.29.9000

70359-46-5 - Isicelo:

I-Brimonidine Tartrate (i-CAS: 70359-46-5) i-blocker ekhethiweyo kakhulu ye-α2-receptor, ephuhliswe ngempumelelo yi-US Inkampani ye-Allergan, yonyango lwamehlo.Inokunciphisa uxinzelelo lwe-intraocular (IOP).I-Brimonidine Tartrate isisombululo se-ophthalmic saling kwimarike yifomu ye-Brimonidine Tartrate, eliyeza elilungileyo le-IOP-lehlisa i-glaucoma evulekile-engileyo engapheliyo kunye nonyango lwe-ocular hypertension yezigulana, kodwa nakumanqanaba e-argon laser IOP.Isisombululo se-Brimonidine Tartrate ophthalmic sineendlela ezimbini zesenzo ngokunciphisa imveliso ye-aqueous humor kunye nokwandisa i-pigment layer ye-liquid scleral outflow therapy ngeenjongo zonyango.Emva kokulahla iliso, umphumo ukhawuleza, kwaye unokufikelela kwincopho xa usebenzisa ukuya kwi-2h, kwaye ixesha elisebenzayo linokugcina i-12h.Igazi liyakwazi ukubona kuphela iithontsi zamachiza.Le mveliso ine-metabolism yokuqala yokudlula kwisibindi, kwaye i-metabolites ekhutshwe kumchamo ngezintso.Ukufakwa kwenkqubo kunye nokusabalalisa akuchaphazeli, kwaye abantu abadala abafuni ukulungiswa kwedosi.I-Brimonidine Tartrate isisombululo se-ophthalmic xa kuthelekiswa nezinye i-α-blockers, i-fat-soluble incinci, ngelixa ingekho lula ukudlula umqobo wegazi-ingqondo kwaye ayivelisi i-sedation, hypotension kunye nezinye i-clonidine central reactions ezimbi.I-Brimonidine Tartrate Ophthalmic Solution ikhetha kakhulu i-α2-adrenergic receptors, kunye ne-α2 / α1 umlinganiselo we-receptor affinity ngaphezu kwamaxesha e-1000.Umphumo we-alpha 2 receptors unokukhokelela ekunciphiseni uxinzelelo lwe-intraocular.Kwaye indima ye-alpha 1 i-receptors ingakhokelela kwi-vascular contraction, ukuchithwa kwe-eyelid okanye ukunciphisa kunye nokunciphisa umfundi.Ukusetyenziswa kwexesha elide kwale mveliso akusayi kubangela ukudakumba ngokukhawuleza.Ukongezelela, xa kuthelekiswa ne-β-blockers, i-Brimonidine Tartrate eyehlayo kwimiphumo emincinci ye-cardiovascular effects, ayinayo impembelelo ekusebenzeni kwemiphunga, ngoko ifanelekile kwizigulane ezikhubazekileyo ze-β-blockers.Ngaphaya koko, xa isetyenziswa yodwa i-β-blocker, ayinakufezekisa iinjongo zonyango, kwaye unokonyusa ngaxeshanye i-FDA.

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