ICarvedilol Phosphate Hemihydrate CAS 610309-89-2 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili weCarvedilol Phosphate Hemihydrate (CAS: 610309-89-2) enomgangatho ophezulu.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, amancinci kunye nezixa ezininzi ezikhoyo.Thenga iCarvedilol Phosphate Hemihydrate,Please contact: alvin@ruifuchem.com
AbaPhakathi abanxulumeneyo beCarvedilol
Igama leMchiza | Carvedilol Phosphate Hemihydrate |
Izithethantonye | BM 14190 Phosphate Hemihydrate;1-(9H-Carbazol-4-yloxy) -3-[2-(2-Methoxyphenoxy)ethylamino]propan-2-olphosphoricacidhydrate |
Ubume beStokhwe | Ikhona evenkileni |
Inombolo yeCAS | 610309-89-2 |
Ifomula yeemolekyuli | C24H26N2O4.H3PO4.0.5H2O |
Ubunzima beMolekyuli | 513.47 g/mol |
I-COA kunye ne-MSDS | Iyafumaneka |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | Umgubo weCrystalline oMhlophe | Iyahambelana |
Amanzi nguKarl Fischer | ≤2.50% | Iyahambelana |
Izinto ezinxulumeneyo | ≤0.50% | Iyahambelana |
Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.5% |
I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engenamoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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I-Carvedilol Phosphate Hemihydrate (i-CAS: 610309-89-2) i-blocking ekhethiweyo i-α1-receptor kunye ne-blocker engakhethiyo ye-β-receptor, akukho mayeza asebenzayo e-Sympathimetic asebenzayo, i-bioavailability ye-10 ~ 47%, engachatshazelwa kukutya, umphumo kwi-α1 -i-receptor iphantsi kakhulu kune-β1-kunye ne-β2-receptor, i-intensity ratio ye-β1-kunye ne-β2-receptor blockade yi-1: 10 ~ 1: 100.Umphumo we-β 1-receptor blockade malunga ne-1/2 ye-labetalol, kwaye i-blockade yayo ye-α1 ibuthakathaka kune-prazosin.Inokwandisa imithambo yegazi, inciphise ukunganyangeki kwemithambo yegazi, ivule imithambo ye-coronary kunye nezintso, kwaye inciphise uxinzelelo lwe-pulmonary wedge.Inempembelelo ecacileyo yokukhusela kwi-myocardial hypoxia kunye nokulimala kwe-myocardial ebangelwa yi-myocardial infarction, enokuthi ihambelane nokuthintela i-β-receptor, enokunciphisa ukuhla kwe-myocardial glycogen kunye nokunyuka kwe-pH, kunye nokunciphisa ubukhulu be-infarct.
ICarvedilol Phosphate Hemihydrate isetyenziselwa ukunyanga uxinzelelo lwegazi oluphakathi ukuya koluphakathi kwaye ingasetyenziswa yodwa okanye idityaniswe namanye amachiza okulwa noxinzelelo lwegazi (ingakumbi i-thiazide diuretics).Ngophawu lokungaphumeleli kwentliziyo engapheliyo.
ICarvedilol Phosphate Hemihydrate yinto engakhethiyo i-β/α-1 receptor blocker.I-Carvedilol inqanda i-lipid peroxidation kunye ne-IC50 ye-5 μM.I-Carvedilol yi-arhente ye-antihypertensive eneenjongo ezininzi enokuthi ikwazi ukufunda i-angina pectoris kunye nokungaphumeleli kwentliziyo.