8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS 100331-89-3 Indacaterol Maleate Intermediate Factory

Inkcazelo emfutshane:

8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline

CAS: 100331-89-3

Imbonakalo: Okumhlophe-Kumhlophe ukuya kumgubo otyheli

Ubunyulu: >95.0% (HPLC)

Phakathi kwe-Indacaterol Maleate (CAS: 753498-25-8)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline
Izithethantonye 8-(Benzyloxy)-5-(2-Bromoacetyl)quinolin-2(1H)-enye;5-(Bromoacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone;5-(2-Bromo-1-Oxoethyl)-8-Benzyloxy-2(1H)-Quinolinone;5-Bromoacetyl-8-Benzyloxycarbostyril
Inombolo yeCAS 100331-89-3
Ubume beStokhwe Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli C18H14BrNO3
Ubunzima beMolekyuli 372.21
Indawo yokunyibilika 192.0 ~ 194.0℃
Indawo yokubilisa 602.6±55.0℃ kwi-760 mmHg
Ukuxinana 1.479±0.06 g/cm3
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo I-Off-White ukuya kwiPowder etyheli
Ubunyulu / Indlela yokuHlalutya >95.0% (HPLC)
Ukufuma (KF) <1.00%
Intsalela ekutshisweni <0.50%
Ukungcola A <3.00% (5-Acetyl-8-(Benzyloxy)quinolin-2(1H)-enye)
Nakuphi na Okunye Ukungcola Okukodwa <1.50%
Ukungcola ngokupheleleyo <5.00%
I-Infrared Spectrum Iyahambelana noLwakhiwo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa I-Indacaterol Maleate (CAS: 753498-25-8) Phakathi

Ukupakishwa kunye noGcino:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
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100331-89-3 - Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi okhokelayo kunye nomthengisi we-8-Benzyloxy-5- (2-Bromoacetyl) -2-Hydroxyquinoline (CAS: 100331-89-3) enomgangatho ophezulu, iphakathi ngokuqhelekileyo kwi ukuhlanganiswa kwe-Indacaterol Maleate (CAS: 753498-25-8).

I-Indacaterol Maleate (CAS: 753498-25-8) yinto entsha, i-ultra-long-acting, iqala ngokukhawuleza i-β (2) -adrenoceptor agonist kunye ne-bronchodilator.Isetyenziselwa unyango lwezifo ezingapheliyo ze-pulmonary (COPD) kunye ne-asthma.I-Arhente ye-European Medicines Agency (EMA) ivume i-indacaterol njengechiza kwi-2009 phantsi kwegama lokuthengisa i-Onbrez ngelixa e-United States i-Food and Drug Administration ivume phantsi kwegama lokuthengisa i-Arcapta kwi-2011. Ichiza lenziwa njengefom yetyuwa ye-malate.Kwakhona, i-indacaterol yi-molecule ye-chiral;nangona kunjalo, kuphela i-R-enantiomer ecocekileyo isasazwa.

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