I-Rolapitant Hydrochloride Hydrate Intermediate CAS 1214741-21-5 Ubunyulu > 98.5% (HPLC) ee >99.0%
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Rolapitant Hydrochloride Hydrate Intermediate (CAS: 1214741-21-5) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iRolapitant Hydrochloride Hydrate Intermediates,Please contact: alvin@ruifuchem.com
| Igama leMchiza | (3R,7aR)-3-(tert-Butyl)-1-Hydroxy-7a-Vinyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-enye |
| Izithethantonye | I-Rolapitant ePhakathi 1;(3R,7aR) -3-(1,1-Dimethylethyl) -7a-Ethenyltetrahydro-1-Hydroxy-3H,5H-Pyrrolo[1,2-c]oxazol-5-enye;3-(1,1-Dimethylethyl)-7a-Ethenyltetrahydro-1-Hydroxy-(3R,7aR)-3H,5H-Pyrrolo[1,2-c]oxazol-5-enye |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 1214741-21-5 |
| Ifomula yeemolekyuli | C12H19NO3 |
| Ubunzima beMolekyuli | 225.28 g/mol |
| Ukuxinana | 1.16±0.10 g/cm3 |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Okumhlophe Okuqinileyo | Okumhlophe Okuqinileyo |
| Amanzi nguKarl Fischer | <0.50% | 0.15% |
| Intsalela kwi-Ignition | <0.50% | <0.10% |
| Ubunyulu / Indlela yokuHlalutya | >98.5% (HPLC) | 99.3% |
| ee Ucoceko | >99.0% (Chiral HPLC) | 99.86% |
| 400MHz 1H-NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-LCMS | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
| Isicelo | I-Intermediate ye-Rolapitant Hydrochloride Hydrate (CAS: 914462-92-3) | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ekuchaseni ukukhanya kunye nokufuma, thintela umlilo.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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(3R,7aR)-3-(tert-Butyl)-1-Hydroxy-7a-Vinyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-enye (CAS: 1214741-21-5) iphakathi kweRolapitant IHydrochloride Hydrate (CAS: 914462-92-3).I-Rolapitant Hydrochloride Hydrate isetyenziselwa ukuthintela ukulibaziseka kwesicaphucaphu kunye nokuhlanza okuhambelana nezifundo zokuqala kunye nokuphinda ze-emetogenic cancer cancer chemotherapy.I-Rolapitant Hydrochloride Hydrate, eyafunyanwa ekuqaleni ngu-Schering-Plough kwaye kamva yaphuhliswa yi-TESARO, Inc., yavunywa yi-FDA ngoSeptemba 2015 ukuthintela ukulibaziseka kwe-chemotherapy-induced nausea kunye nokuhlanza (CINV) ngokudibanisa nezinye i-antiemetic agents.
