I-Apixaban i-Intermediate CAS 1267610-26-3 1-(4-Aminophenyl) -3-Morpholino-5,6-Dihydropyridin-2 (1H) -enye Ukuhlanjululwa ≥99.0% (HPLC)
I-Ruifu Chemical ngumenzi ohamba phambili we-1- (4-Aminophenyl) -3-Morpholino-5,6-Dihydropyridin-2 (1H)-enye (i-CAS: 1267610-26-3) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga i-Apixaban intermediates,Please contact: alvin@ruifuchem.com
Igama leMchiza | 1-(4-Aminophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-enye |
Izithethantonye | I-1-(4-Aminophenyl) -5,6-Dihydro-3- (4-Morpholinyl) -2 (1H) -Pyridinone;Apixaba Inretmediate A;Apixaban int.A;Ukungcola kwe-Apixaban S;Ukungcola kwe-Apixaban 47;Ukungcola okuNxulumene ne-Apixaban 2 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 1267610-26-3 |
Ifomula yeemolekyuli | I-C15H19N3O2 |
Ubunzima beMolekyuli | 273.33 g/mol |
Indawo yokunyibilika | >246℃ |
Ukuxinana | 1.277±0.06 g/cm3 |
I-COA kunye ne-MSDS | Iyafumaneka |
Imvelaphi | Shanghai, China |
Udidi | Phakathi kwe-Apixaban (CAS: 503612-47-3) |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | I-Off-White ukuya kwiPowder eKhanyayo etyheli | I-Off-White Powder |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) | 99.65% |
Max.Ukungacoceki komntu | ≤0.20% | 0.12% |
Ilahleko ekomisweni | ≤0.50% | 0.3% |
I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
NMR Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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I-1- (4-Aminophenyl) -3-Morpholino-5,6-Dihydropyridin-2 (1H)-enye (i-CAS: 1267610-26-3) iphakathi kwi-synthesis ye-Apixaban (CAS: 503612-47-3) , I-inhibitor enamandla, ngokuthe ngqo, ekhethiweyo, kunye neyomlomo esebenzayo ye-coagulation factor Xa.I-Apixaban yinto entsha yomlomo yomlomo enokuba luncedo ekuthinteleni i-venous thromboembolism kwi-hip epheleleyo, utyando lwamathambo okutshintshwa kwamadolo kunye ne-stroke kunyango lwesigulane esine-venous thromboembolic disorder okanye nge-fibrillation ye-atrial.U-Eliquis (Apixaban), i-inhibitor echanekileyo ye-factor Xa (FXa), yavunywa yiKomishoni yaseYurophu ngoMeyi 18, i-2011 yokuthintela iziganeko ze-venous thromboembolic (VTE) kwizigulane zabantu abadala abaye bafumana utyando olukhethiweyo lwe-hip okanye idolo.