I-4-Isothiocyanato-2-(Trifluoromethyl)benzonitrile CAS 143782-23-4 Enzalutamide Intermediate Purity>98.0% (GC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile (CAS: 143782-23-4) enomgangatho ophezulu, ophakathi kwe-Enzalutamide (CAS: 915087-33-1).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga i-Enzalutamide Intermediates,Please contact: alvin@ruifuchem.com
Igama leMchiza | I-4-Isothiocyanato-2-(Trifluoromethyl) benzonitrile |
Izithethantonye | I-4-Cyano-3-(Trifluoromethyl)phenyl Isothiocyanate;Isothiocyanic Acid 4-Cyano-3-(Trifluoromethyl)phenyl Ester;I-4-Isothiocyanato-2-Trifluoromethylbenzonitrile;3-Fluoro-4-Methylphenylisothiocyanate |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 143782-23-4 |
Ifomula yeemolekyuli | I-C9H3F3N2S |
Ubunzima beMolekyuli | 228.19 g/mol |
Indawo yokunyibilika | 39.0 ukuba 43.0℃ |
Indawo yokubilisa | 331℃ |
Indawo yokuflasha | 154℃ |
Ukuxinana | 1.31 |
Inovakalelo | Ubunobuzaza bokufuma, Bunobuzaza bubushushu |
I-COA kunye ne-MSDS | Iyafumaneka |
Isampulu | Iyafumaneka |
Imvelaphi | Shanghai, China |
Uphawu | Ruifu Chemical |
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | I-Off-White Powder | I-Off-White Powder |
Indawo yokunyibilika | 39.0 ukuba 43.0℃ | 41.2℃ |
Ilahleko ekomisweni | <0.50% | 0.19% |
Ubunyulu / Indlela yokuHlalutya | >98.0% (HPLC) | 98.8% |
I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
Isicelo | Phakathi kwe-Enzalutamide (CAS: 915087-33-1) |
Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
I-H302 + H312 + H332: Iyingozi xa iginyiwe, xa idibene nolusu okanye xa itsaliwe.
I-H315: Ibangela ukucaphuka kwesikhumba.
I-H319: Ibangela ukucaphuka kwamehlo okunzulu.
I-H335: Inokubangela ukucaphuka kokuphefumula.
I-P501: Lahla iziqulatho/isikhongozeli kwiziko elivunyiweyo lokulahla inkunkuma.
P261: Kuphephe ukuphefumla uthuli/ umsi/ igesi/ inkungu/ umphunga/ isitshizi.
P270: Ungatyi, ungaseli okanye utshaye xa usebenzisa le mveliso.
P271: Sebenzisa ngaphandle kuphela okanye kwindawo engenamoya.
P264: Hlamba ulusu ngononophelo emva kokuphatha.
P280: Nxiba iiglavu ezikhuselayo/ iimpahla ezikhuselayo/ ukhuseleko lwamehlo/ ukhuseleko lobuso.
P337 + P313: Ukuba ukucaphuka kwamehlo kuyaqhubeka: Fumana iingcebiso zonyango/uhoyo.
P305 + P351 + P338: UKUBA EMEHLWENI: Hlanza ngononophelo ngamanzi imizuzu emininzi.Susa iilensi zoqhagamshelwano, ukuba zikhona kwaye kulula ukuzenza.Qhubeka uhlamba.
P332 + P313: Ukuba ukurhawuzelelwa kwesikhumba kwenzeka: Fumana iingcebiso zonyango / ingqalelo.
P362: Khulula impahla engcolisekileyo kwaye uyihlambe phambi kokuba uyisebenzise kwakhona.
P301 + P312 + P330: UKUBA IYAGINWA: Biza iPOISON CENTER/ugqirha ukuba uziva ungaphilanga.Hlamba umlomo.
P302 + P352 + P312: UKUBA ULUSU: Hlamba ngamanzi amaninzi.Biza iPOISON CENTRE/ugqirha ukuba uziva ungaphilanga.
I-P304 + P340 + P312: UKUBA IHAWILE: Susa umntu emoyeni omtsha kwaye uhlale ukhululekile ukuphefumla.Fowunela iPOISON CENTRE/ugqirha ukuba uziva ungaphilanga.
I-P403 + P233: Gcina kwindawo engenamoya.Gcina isikhongozeli sivalwe ngokuqinileyo.
P405: Ivenkile itshixiwe.
I-4-Isothiocyanato-2- (Trifluoromethyl) benzonitrile (CAS: 143782-23-4) isetyenziswe njengendawo ephakathi kwe-Enzalutamide (CAS: 915087-33-1).I-Enzalutamide (XTANDI) ngumchasi we-androgen receptor womlomo, ovunyiweyo ngophando lwezonyango lwangoku kunye ne-US FDA (Ukutya kunye noLawulo lweDrug), kuphuhliso lwe-post-chemotherapy metastatic castration tolerance yonyango lomhlaza we-prostate (oko kukuthi izigulane ezinomhlaza we-prostate). emva kwechemotherapy, umhlaza okanye iiseli zomhlaza zisakhula kwizigulana ezinjalo), unokwandisa ukusinda kwezigulana.Ngo-Agasti ka-2012, i-FDA yaseMelika yavuma i- enzalutamide yonyango lwe-metastatic castration-resistant cancer cancer (mCRPC) kwizigulana ebezikhe zanyangwaDocetaxel.