I-Lesinurad Intermediate CAS 1533519-84-4 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4- (4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5 (4H) -Thione (CAS: 1533519-84-4) ngomgangatho ophezulu, ophakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iLesnurad Intermediates,Please contact: alvin@ruifuchem.com
Igama leMchiza | 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione |
Izithethantonye | 4-(4-Cyclopropylnaphthalen-1-yl) -4H-1,2,4-Triazole-3-Thiol;4-(4-Cyclopropyl-1-Naphthalenyl) -2,4-Dihydro-3H-1,2,4-Triazole-3-Thione;Lesinurad INT3;Ukungacoceki kweLesinurad 20 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 1533519-84-4 |
Ifomula yeemolekyuli | I-C15H13N3S |
Ubunzima beMolekyuli | 267.35 g/mol |
Indawo yokubilisa | 435.2±38.0℃ |
Ukuxinana | 1.41±0.10 g/cm3 |
I-COA kunye ne-MSDS | Iyafumaneka |
Imvelaphi | Shanghai, China |
Udidi | Umbindi weLesinurad (CAS: 878672-00-5) |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | I-Off-White Powder | I-Off-White Powder |
Amanzi nguKarl Fischer | <0.50% | 0.10% |
Ilahleko ekomisweni | <0.50% | 0.40% |
Intsalela kwi-Ignition | <0.50% | 0.15% |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.8% |
I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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I-L-Phenylalanine (H-Phe-OH) (i-CAS: 63-91-2) isetyenziswe njengendawo ephakathi kwi-synthesis yeLesinurad (CAS: 878672-00-5).ILesinurad sisithinteli esikhethiweyo sokufunxa kwakhona kwe-uric acid esetyenziswa ngokudityaniswa nezinye ii-agent kunyango lwegawuthi.I-Lesinurad (igama lohlobo lwe-Zurampic) yeyokuqala ekhethiweyo ye-uric acid reabsorption inhibitor (SURI) evunywe yi-FDA.Isebenza ngokunqanda umthuthi we-urate, i-URAT1, ejongene noninzi lwe-renal rebsorption ye-uric acid.I-Lesinurad yi-urate transporter inhibitor yokunyanga i-hyperuricemia ehambelana ne-gout kwizigulane ezingakhange zifikelele kwinqanaba le-serum ye-uric acid kunye ne-xanthine oxidase inhibitor yodwa.Ifumene imvume ye-FDA ngoDisemba 22, 2015. IKhomishini yaseYurophu inike isigunyaziso sokuthengisa esisebenzayo kwi-European Union kwi-18 kaFebruwari 2016.