I-Lesinurad Intermediate CAS 1533519-84-4 Ubunyulu > 99.0% (HPLC)

Inkcazelo emfutshane:

Igama leMichiza: 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione

CAS: 1533519-84-4

Ubunyulu: >99.0% (HPLC)

Imbonakalo: I-Off-White Powder

Umbindi weLesinurad (CAS: 878672-00-5)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4- (4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5 (4H) -Thione (CAS: 1533519-84-4) ngomgangatho ophezulu, ophakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iLesnurad Intermediates,Please contact: alvin@ruifuchem.com

Lesinurad AbaPhakathi:

Iipropati zeMichiza:

Igama leMchiza 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-Triazole-5(4H)-Thione
Izithethantonye 4-(4-Cyclopropylnaphthalen-1-yl) -4H-1,2,4-Triazole-3-Thiol;4-(4-Cyclopropyl-1-Naphthalenyl) -2,4-Dihydro-3H-1,2,4-Triazole-3-Thione;Lesinurad INT3;Ukungacoceki kweLesinurad 20
Ubume beStokhwe Kwi-Stock, iMveliso yoRhwebo
Inombolo yeCAS 1533519-84-4
Ifomula yeemolekyuli I-C15H13N3S
Ubunzima beMolekyuli 267.35 g/mol
Indawo yokubilisa 435.2±38.0℃
Ukuxinana 1.41±0.10 g/cm3
I-COA kunye ne-MSDS Iyafumaneka
Imvelaphi Shanghai, China
Udidi Umbindi weLesinurad (CAS: 878672-00-5)
Uphawu Ruifu Chemical

Iinkcukacha:

Izinto ImiGangatho yokuHlola Iziphumo
Imbonakalo I-Off-White Powder I-Off-White Powder
Amanzi nguKarl Fischer <0.50% 0.10%
Ilahleko ekomisweni <0.50% 0.40%
Intsalela kwi-Ignition <0.50% 0.15%
Ubunyulu / Indlela yokuHlalutya >99.0% (HPLC) 99.8%
I-Infrared Spectrum Ngokungqinelana noLwakhiwo Iyahambelana
I-1H NMR Spectrum Ngokungqinelana noLwakhiwo Iyahambelana
Ukuqukumbela Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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Izinto eziluncedo:

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Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.

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Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

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Isicelo:

I-L-Phenylalanine (H-Phe-OH) (i-CAS: 63-91-2) isetyenziswe njengendawo ephakathi kwi-synthesis yeLesinurad (CAS: 878672-00-5).ILesinurad sisithinteli esikhethiweyo sokufunxa kwakhona kwe-uric acid esetyenziswa ngokudityaniswa nezinye ii-agent kunyango lwegawuthi.I-Lesinurad (igama lohlobo lwe-Zurampic) yeyokuqala ekhethiweyo ye-uric acid reabsorption inhibitor (SURI) evunywe yi-FDA.Isebenza ngokunqanda umthuthi we-urate, i-URAT1, ejongene noninzi lwe-renal rebsorption ye-uric acid.I-Lesinurad yi-urate transporter inhibitor yokunyanga i-hyperuricemia ehambelana ne-gout kwizigulane ezingakhange zifikelele kwinqanaba le-serum ye-uric acid kunye ne-xanthine oxidase inhibitor yodwa.Ifumene imvume ye-FDA ngoDisemba 22, 2015. IKhomishini yaseYurophu inike isigunyaziso sokuthengisa esisebenzayo kwi-European Union kwi-18 kaFebruwari 2016.

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