I-Lesinurad Intermediate CAS 1533519-85-5 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi okhokelayo we-Methyl 2-[[4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio]acetate (CAS: 1533519-85-5) kunye nomgangatho ophezulu, ophakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iLesnurad Intermediates,Please contact: alvin@ruifuchem.com
Igama leMchiza | Methyl 2-[[4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio]acetate |
Izithethantonye | Lesinurad INT4;Ukungcola kweLesinurad 11;IMethyl {[4-(4-Cyclopropyl-1-Naphthyl)-4H-1,2,4-Triazol-3-yl]sulfanyl}acetate |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 1533519-85-5 |
Ifomula yeemolekyuli | I-C18H17N3O2S |
Ubunzima beMolekyuli | 339.41 g/mol |
Indawo yokubilisa | 546.4±60.0℃ |
Ukuxinana | 1.38±0.10 g/cm3 |
I-COA kunye ne-MSDS | Iyafumaneka |
Imvelaphi | Shanghai, China |
Udidi | Umbindi weLesinurad (CAS: 878672-00-5) |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | I-Off-White Powder | I-Off-White Powder |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.6% |
Ukungacoceki okukhulu okukodwa | <0.50% | 0.2% |
Ukungcola ngokupheleleyo | <1.00% | 0.4% |
Amanzi nguKarl Fischer | <0.50% | 0.1% |
Ilahleko ekomisweni | <0.50% | 0.1% |
Intsalela kwi-Ignition | <0.20% | 0.1% |
I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
I-1H NMR Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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I-Methyl 2-[[4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-Triazol-3-yl]thio]acetate (CAS: 1533519-85-5) isetyenziswa njengendawo ephakathi yeLesinurad. (CAS: 878672-00-5).Ivunywe yi-FDA ngasekupheleni kwe-2015, i-lesinurad yi-urrate anion exchange transporter 1 (URAT1) inhibitor yokusetyenziswa kunyango lwe-gout.I-Ardea Biosciences, eyi-subsidiary ye-AstraZeneca, iphuhlise i-lesinurad ukuba isetyenziswe kunyango oludibeneyo kunye ne-xanthine oxidase inhibitors kunyango lwe-hyperuricaemia ehambelana ne-gout.Inkqubo yokwamkelwa iyaqhubeka kwamanye amazwe aliqela kwihlabathi liphela, kunye neKomiti yeEMA yeeMveliso zaMayeza ngokuSetyenziswa koLuntu inika lesinurad uluvo olulungileyo lokusetyenziswa njengonyango loncediso oludityaniswe ne-xanthine oxidase inhibitors ukunyanga i-hyperuricaemia.