I-4-Cyclopropylnaphthalen-1-Amine Hydrochloride CAS 1533519-92-4 Lesinurad Intermediate Purity>99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-4-Cyclopropylnaphthalen-1-Amine Hydrochloride (CAS: 1533519-92-4) enomgangatho ophezulu, ophakathi kweLesinurad (CAS: 878672-00-5).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iLesnurad Intermediates,Please contact: alvin@ruifuchem.com
| Igama leMchiza | I-4-Cyclopropylnaphthalen-1-Amine Hydrochloride |
| Izithethantonye | Lesinurad ePhakathi 3;I-4-Cyclopropylnaphthalen-1-Amine HCl;I-4-Cyclopropyl-1-Naphthalenamine Hydrochloride;I-4-Cyclopropyl-1-Naphthalenamine HCl;Ukungcola kweLesinurad 14 HCl |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 1533519-92-4 |
| Ifomula yeemolekyuli | I-C13H14ClN |
| Ubunzima beMolekyuli | 219.71 g/mol |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Udidi | Umbindi weLesinurad (CAS: 878672-00-5) |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | I-Off-White ukuya kwiPowder eKhanyayo etyheli | I-Off-White Powder |
| Ilahleko ekomisweni | <0.50% | 0.2% |
| Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.3% |
| Ukungcola ngokupheleleyo | <1.00% | 0.7% |
| I-1 H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-LCMS | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
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I-4-Cyclopropylnaphthalen-1-Amine Hydrochloride (CAS: 1533519-92-4) isetyenziswe njengendawo ephakathi kwi-synthesis yeLesinurad (CAS: 878672-00-5).Ivunywe yi-FDA ngasekupheleni kwe-2015, iLesinurad yi-urrate anion exchange transporter 1 (URAT1) inhibitor yokusetyenziswa kunyango lwe-gout.I-Ardea Biosciences, eyi-subsidiary ye-AstraZeneca, iphuhlise iLesinurad ukuba isetyenziswe kunyango oludibeneyo kunye ne-xanthine oxidase inhibitors kunyango lwe-hyperuricaemia ehambelana ne-gout.Inkqubo yokuvunywa iyaqhubeka kwamanye amazwe aliqela kwihlabathi liphela, kunye neKomiti yeEMA yeeMveliso zaMachiza ngokuSetyenziswa koLuntu inika uLesinurad uluvo oluhle lokusetyenziswa njengonyango loncediso oludityaniswe ne-xanthine oxidase inhibitors ukunyanga i-hyperuricaemia.
