Methyl 2-Acetylamino-3-Chloropropionate CAS 18635-38-6 Ramipril Intermediate Purity ≥99.0% (HPLC)
I-Ruifu Chemical ngumenzi ohamba phambili weMethyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6) enomgangatho ophezulu, ophakathi kweRamipril (CAS 87333-19-5).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iMethyl 2-Acetylamino-3-Chloropropionate,Please contact: alvin@ruifuchem.com
| Igama leMchiza | I-Methyl 2-Acetylamino-3-Chloropropionate |
| Izithethantonye | I-LN-Acetyl-β-Chloroalanine iMethyl Ester;I-Methyl (R) -2-Acetamido-3-Chloropropanoate;I-N-Acetylmine-3-Chloro-L-Alaninemethyl Ester;I-Methyl N-Acetyl-3-Chloro-L-Alaninate;I-Methyl N-Acetyl-3-Chloroalaninate;Ac-DL-Ala(Cl)-OMe |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 18635-38-6 |
| Ifomula yeemolekyuli | I-C6H10ClNO3 |
| Ubunzima beMolekyuli | 179.60 g/mol |
| Indawo yokunyibilika | 102.0 ~ 105.0℃ |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Mhlophe ukuya kwi-Off-White Powder | Iyahambelana |
| Indawo yokunyibilika | 102.0 ~ 105.0℃ | 102.0 ~ 105.0℃ |
| Ilahleko ekomisweni | ≤0.50% | 0.26% |
| Ukujikeleziswa okuthe ngqo | -13.0 ° ukuya -16.0 ° | -13.15 ° |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) | 99.27% |
| I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
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I-Methyl 2-Acetylamino-3-Chloropropionate (CAS: 18635-38-6), phakathi kweRamipril (CAS 87333-19-5).I-Ramiprilat yi-metabolite esebenzayo ye-ramipril kwaye isebenza njenge-angiotensin-converting enzyme inhibitor (pKi = 9.08 entliziyweni yomntu) ukucinezela ukuguqulwa kwe-angiotensin I ukuya kwi-angiotensin II kunye nokuthotywa kwe-bradykinin, ngaloo ndlela ikhusela i-vasoconstriction.Ngaphaya koko, i-ramiprilat ixelwa ukuba iphazamise ukujoliswa kwe-B2 kinin receptors kwi-endothelial cell membranes ikhusela ngakumbi ukubonakaliswa kwebradykinin.Ukongeza kwiimpembelelo zayo ze-cardioprotective kuzo zombini iimodeli zezilwanyana kunye nezifundo zeklinikhi, i-ramiprilat iye yaxelwa ukuba inqanda i-matrix metalloproteinase-3 kunye -9 umsebenzi kwi-fistula ye-Crohn yesifo esizimeleyo.
