I-Side Chain ye-Docetaxel CAS 196404-55-4 Docetaxel Intermediate Purity>99.0% (Titration)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Side Chain ye-Docetaxel (i-CAS: 196404-55-4) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iChain esecaleni yeDocetaxel,Please contact: alvin@ruifuchem.com
Igama leMchiza | (4S,5R)-3-(tert-Butoxycarbonyl)-2-(4-Methoxyphenyl)-4-Phenyloxazolidine-5-Carboxylic Acid |
Izithethantonye | Ikhonkco elisecaleni leDocetaxel;(4S,5R) -3-tert-Butoxycarbony-2- (4-anisyl) -4-Phenyl-5-Oxazolidinecarboxylic Acid;(4S,5R)-2-(4-Methoxy-phenyl)-3-N-Boc-4-Phenyl-3,5-Oxazolidine Carboxylic Acid |
Ubume beStokhwe | Kwisitokhwe, isikali soRhwebo |
Inombolo yeCAS | 196404-55-4 |
Ifomula yeemolekyuli | C22H25NO6 |
Ubunzima beMolekyuli | 399.44 g/mol |
Indawo yokunyibilika | 127.0 ~ 137.0℃ |
Ukuxinana | 1.238 |
Ugcino Temp. | Indawo epholileyo neyomileyo (2~8℃) |
Ukuhambisa ngenqanawe | Okuqhelekileyo |
I-COA kunye ne-MSDS | Iyafumaneka |
Imvelaphi | Shanghai, China |
Uphawu | Ruifu Chemical |
Inkcazelo yoKhuseleko | 24/25 - Gwema ukudibana nolusu kunye namehlo. |
Ikhowudi ye-HS | 2932999029 |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe | Iyahambelana |
Indawo yokunyibilika | 127.0 ~ 137.0℃ | 133.8 ~ 135.4℃ |
Ukujikeleziswa okuthe ngqo [α]20/D | +65.0 ° ukuya +75.0 ° | + 72,4 ° |
UV | ubuninzi 227nm | Iyahambelana |
Into eNxulumene nayo (nge-HPLC) | ≤2.00% | 0.7% |
Ilahleko ekomisweni | <0.50% | 0.2% |
Ubunyulu / Indlela yokuHlalutya | >99.0% (NgeTitration) | 99.4% |
I-1 H NMR Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engenamoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
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(4S,5R) -3-(tert-Butoxycarbonyl)-2-(4-Methoxyphenyl)-4-Phenyloxazolidine-5-Carboxylic Acid (I-Side Chain of Docetaxel) (CAS: 196404-55-4) yinto ephakathi / engcolileyo. yeDocetaxel (CAS: 114977-28-5) kunye neDocetaxel Trihydrate (CAS: 148408-66-6).Isenokusetyenziswa ukwenza i-quinoline-docetaxel analogue ezibonisa umsebenzi wokulwa nomhlaza.
I-Docetaxel yi-taxane, i-antineoplastic, kunye neyeza le-antiticancer elisetyenziselwa ukunyanga umhlaza webele we-metastatic wasekhaya, nasemva kokusilela kwonyango lwe-cisplatin.Ukusebenza kwayo kwe-anti-tumor kuye kwangqinwa kwiimvavanyo ze-vitro ukuba zibe ngamaxesha angama-1.3-12 e-paclitaxel.Uphononongo lwezonyango lubonise ukuba lusebenza ngakumbi kune-paclitaxel ngokuchasene nomhlaza webele onganyangekiyo we-anthracycline.I-Docetaxel okwangoku yolona nyango lusebenzayo kudidi lwesibini lomhlaza wamabele onganyangekiyo we-anthracycline.Kunyango lweseli enye kunye nechemotherapy edityanisiweyo yomhlaza wemiphunga weseli ongemncinci, lelinye lamachiza asebenzayo.Ingasetyenziselwa umhlaza wesibeleko, kunye nokufunda i-antibiotics, ibhayoloji yeseli, ukubonakaliswa kweeseli, i-neuroscience, i-apoptosis, kunye nemijikelo yeeseli.Ikwasetyenziselwa ukufunda ukulahleka kweenwele okubangelwa yi-docetaxel chemotherapy, kunye nokuthintela kunye nokunyanga umhlaza wemiphunga weseli encinci kwizigulana ezingachanekanga kwichemotherapy.Ikwasetyenziselwa ukuphanda iindima ze-hypoxia-inducible factor-1α kunye ne-2α kwi-androgen-insensitive cell cancer cancer.