3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Intermediate Purity>98.0% (HPLC)

Inkcazelo emfutshane:

Igama leKhemikhali: 3-Chloro-4-(3-Fluorobenzyloxy)aniline

CAS: 202197-26-0

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Imdaka ukuya kwiPowder emnyama

Phakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-3-Chloro-4- (3-Fluorobenzyloxy) ianiline (i-CAS: 202197-26-0) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iLapatinib Intermediates,Please contact: alvin@ruifuchem.com

AbaPhakathi beLapatinib:

Isiseko seLapatinib	I-CAS 231277-92-2
ILapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
Isodium methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
I-2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
I-6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Iipropati zeMichiza:

Igama leMchiza	3-Chloro-4-(3-Fluorobenzyloxy)aniline
Izithethantonye	3-Chloro-4-[(3-Fluorophenyl)methoxy]aniline;4-(3-Fluorobenzyloxy)-3-Chlorobenzenamine;ILapatinib ePhakathi B
Ubume beStokhwe	Kwi-Stock, iMveliso yoRhwebo
Inombolo yeCAS	202197-26-0
Ifomula yeemolekyuli	I-C13H11ClFNO
Ubunzima beMolekyuli	251.69 g/mol
Indawo yokunyibilika	78.0 ukuba 82.0℃
Ukuxinana	1.306±0.06 g/cm3
I-COA kunye ne-MSDS	Iyafumaneka
Isampulu	Iyafumaneka
Imvelaphi	Shanghai, China
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Umdaka ukuya kwiPowder emnyama	Iyahambelana
Indawo yokunyibilika	78.0 ukuba 82.0℃	80.7℃
Ilahleko ekomisweni	<1.00%	Iyahambelana
Intsalela kwi-Ignition	<0.50%	Iyahambelana
Ukungcola okuNxulumeneyo yi-HPLC	<2.00%	0.64%
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)	99.36%
I-1H NMR Spectrum	Ngokungqinelana noLwakhiwo	Iyahambelana
Ukuqukumbela	Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo
Isicelo	Phakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.

202197-26-0 - Ulwazi loKhuseleko:

Ii-ID ze-UN 3077
Ikhowudi yeHS 2921420090
Udidi 9 lweengozi
Ukupakisha Iqela III

202197-26-0 - Isicelo:

I-3-Chloro-4- (3-Fluorobenzyloxy) i-aniline (i-CAS: i-202197-26-0) iphakathi kwi-synthesis yeLapatinib / Lapatinib Ditosylate Monohydrate.
I-Lapatinib lichiza elijolise kumdlavuza webele ophuhliswe yi-British GlaxoSmithKline Co. I-Human ErbB i-receptors iyingxenye ye-I tyrosine kinase (TK) intsapho ye-receptor, kuquka i-ErbB1 (EGFR), i-ErbB2 (HER2), i-ErbB3 (HER3), kunye ne-ErbB4 (HER4) .I-ErbB-1 (EGFR) kunye ne-ErbB-2 (HER-2) i-receptors zihlala zigqithise okanye zitshintshwe ngenye indlela kwizigulane zomhlaza.I-Human epidermal growth factor receptor 2 (ErbB-2, HER-2) yaziwa ngokuba ngumntu oncogene enxulumene ngokusondeleyo nomhlaza webele.Ukubonakaliswa kwayo okuphezulu kumhlaza wamabele kuhlala kuxela kwangaphambili i-lymph node metastasis kunye nokwahlulahlulwa kwethumba elibi, kunye ne-prognosis embi.I-HER-2 yenye yeemolekyuli ekujoliswe kuzo kunyango oluthile lomhlaza wamabele.ILapatinib inokusebenza ngaxeshanye kuyo yomibini i-Her-1 Her-2.Iziphumo zebhayoloji zale ndlela zithintela ukwanda kunye nokukhula kweeseli zethumba zikhulu kakhulu kunokuba zisebenze kwithagethi enye.Indibaniselwano yeLapatinib kunye neCapecitabine isetyenziselwa ukunyanga izigulane ezinomhlaza webele ophezulu okanye we-metastatic ngokugqithiswa kwe-epidermal receptor2 yabantu, esele iphathwe nge-anthracyclines, i-paclitaxel, kunye ne-trastuzumab.Ulingo lwezonyango lubonise ukuba iLapatinib ikwaphatha ngokukuko izigulane zomhlaza zohlobo lwe-HER2 ezinokumelana neHerceptin.