Repaglinide Intermediate CAS 219921-94-5 Ubunyulu > 99.0% (HPLC)
I-Ruifu Chemical ngumenzi ohamba phambili we (S) -3-Methyl-1-[2- (1-Piperidinyl) phenyl] butylamine N-Acetyl-L-Glutamate Ityuwa (CAS: 219921-94-5) kunye nomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga iRepaglinide Intermediates,contact: alvin@ruifuchem.com
Igama leMchiza | (S)-3-Methyl-1-[2-(1-Piperidinyl)phenyl]butylamine N-Acetyl-L-Glutamate Ityuwa |
Izithethantonye | S-PPA |
Ukungcola | Repaglinide EP Ukungcola C / Repaglinide USP Related Compound A |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 219921-94-5 |
Ifomula yeemolekyuli | I-C23H37N3O5 |
Ubunzima beMolekyuli | 435.57 |
Indawo yokunyibilika | 168.0 ~ 171.0℃ |
I-COA kunye ne-MSDS | Iyafumaneka |
Imvelaphi | Shanghai, China |
Uphawu | Ruifu Chemical |
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | Mhlophe ukuya Phantse uMhlophe | Phantse umgubo oMhlophe |
Ukunyibilika | Inyibilika kwiMethanol.Inyibilika kancinane emanzini. Ayinyibiliki kwiDichloromethane | Iyahambelana |
Amanzi nguKarl Fischer | <1.00% | 0.45% |
I-Specific Optical | +30.0 ° ukuya +36.0 ° | + 34.1 ° |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.5% |
Izinto ezinxulumeneyo | (HPLC) | |
Ukungcola ngokupheleleyo | <1.00% | 0.44% |
Nakuphi na Ukungacoceki Okukodwa | <0.80% | 0.31% |
Isomer | <1.00% | 0.08% |
I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo |
Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
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Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
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Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko 41 - Umngcipheko womonakalo omkhulu emehlweni
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S39 -Nxiba ukhuseleko lwamehlo / ubuso.
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
Ikhowudi yeHS 2942000000
(S) -3-Methyl-1-[2- (1-Piperidinyl) phenyl] butylamine N-Acetyl-L-Glutamate Ityuwa (CAS: 219921-94-5) iphakathi / ukungcola kweRepaglinide (CAS: 135062- 02-1).
I-Repaglinide, uhlobo lwamayeza okunyanga isifo seswekile, yi-insulinotropic agent eyeye-non-sulfonylurea.Yaphuhliswa ngu-Boehringer Ingelheim yaseJamani, yaze yaphumelela imvume yi-FDA evela e-United States ngoDisemba 1997. Ngo-1998, yadweliswa ngokulandelelanayo e-United States nakumazwe aseYurophu, kunye negama lemveliso njengeNovoNorm.Isetyenziswa kakhulu kunyango lweklinikhi yohlobo lwesifo sikashukela sohlobo lwe-II (esingaxhomekekanga kwi-insulin) izigulane ezine-hyperglycemia engakwazi ukulawulwa ngokufanelekileyo ngokutya, ukunciphisa umzimba kunye nokuzilolonga.Ngo-2008, i-FDA evela eUnited States yavuma ukuba iye esidlangalaleni kwi-Novo Nordisk ye-Replaglinide + Metformin HCl, Prandimet, kunyango lwe-2 yeswekile.