Lapatinib Intermediate CAS 231278-84-5 Ubunyulu >98.0% (HPLC) Umfanekiso obonakalayo

ILapatinib ePhakathi CAS 231278-84-5 Ubunyulu >98.0% (HPLC)

Inkcazelo emfutshane:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

CAS: 231278-84-5

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Mthubi oMthubi ukuya kuMthubi womgubo oqinileyo

I-API ephakathi (CAS 388082-77-7)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

AbaPhakathi beLapatinib:

Isiseko seLapatinib	I-CAS 231277-92-2
ILapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
Isodium methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
I-2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
I-6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Iipropati zeMichiza:

Igama leMchiza	5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Izithethantonye	ILapatinib ePhakathi 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde
Inombolo yeCAS	231278-84-5
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C26H17ClFN3O3
Ubunzima beMolekyuli	473.90
Indawo yokunyibilika	225.0 ukuba 235.0℃
Ukuxinana	1.407±0.06 g/cm3
Refractive Index	1.694
I-COA kunye ne-MSDS	Iyafumaneka
Imvelaphi	Shanghai, China
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMthubi oMthubi ukuya kumthubi
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)
Indawo yokunyibilika	225.0 ~ 235.0℃
Ilahleko ekomisweni	<1.00%
Intsalela kwi-Ignition	<0.50%
Ukungcola ngokupheleleyo	<2.00%
Iintsimbi ezinzima (njenge Pb)	<20ppm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	I-API ephakathi (CAS 388082-77-7)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

231278-84-5 - Isicelo:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) iphakathi kwe-API (CAS 388082-77-7) ).(i-CAS 388082-77-7) lichiza elijolise kumdlavuza webele ophuhliswe yi-British GlaxoSmithKline Co. I-tyrosine kinase inhibitor enokuthintela ngokufanelekileyo umsebenzi we-tyrosine kinase we-epidermal growth factor receptors 1 kunye ne-2 (ErbB1, ErbB2).Inokwenza ngokukodwa ngeendlela ezahlukeneyo, iqinisekisa ukuba iiseli zomhlaza wamabele azikwazi ukufumana iimpawu zokukhula.Ivimbela i-intracellular EGFR (ErbB-1) kunye ne-HER2 (ErbB-2) iisayithi ze-ATP, ukukhusela i-tumor cell phosphorylation kunye nokusebenza, ukuthintela izibonakaliso eziphantsi kwe-homogeneity kunye ne-heterogeneity ye-EGFR (ErbB-1) kunye ne-HER2 (ErbB-1) ukuncipha.