CAS 242478-38-2 Purity ≥99.5% (HPLC) API
AbaPhakathi abaNxulumene noBonelelo lwezoRhwebo:
CAS: 242478-38-2
(R)-(-)-3-Quinuclidinol CAS: 25333-42-0
(S)-(+)-3-Quinuclidinol CAS: 34583-34-1
I-3-Quinuclidinone Hydrochloride CAS: 1193-65-3
I-1-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline CAS: 22990-19-8
(S)-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline CAS: 118864-75-8
Izithethantonye | iVesicare;1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid |
Inombolo yeCAS | 242478-38-2 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C23H26N2O2·C4H6O4 |
Ubunzima beMolekyuli | 480.56 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe |
Ukuchongwa | Nge-IR;Nge-HPLC |
Ukunyibilika | I-Soluble ngokukhululekileyo kwi-Acetic Acid, Amanzi, iMethanol |
Indawo yokunyibilika | 144.0 ~ 150.0℃ |
Ujikelezo oluKhethekileyo lwe-Optical | +88.0º~+94.0º |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.10% |
3-Quinuclidinol | ≤0.20% |
Succinate Umxholo | 23.5~25.5% |
Isomer ye-Optical | |
Diastereoisomer RS | ≤0.15% |
Diastereoisomer SS | ≤0.15% |
I-Diasteoisomer RR | ≤0.20% |
Izinyibilikisi ezishiyekileyo | |
I-acetone | ≤5000ppm |
Dichloromethane | ≤600ppm |
UToulene | ≤890ppm |
I-Diisopropyl Etere | ≤500ppm |
I-Dimethyl Formamide | ≤880ppm |
Izinto ezinxulumeneyo | |
Nakuphi na Ukungacoceki Okukodwa | ≤0.10% |
Ukungcola ngokupheleleyo | ≤0.50% |
Iintsimbi ezinzima | ≤20ppm |
Ubunyulu / Indlela yokuHlalutya | ≥99.5% (HPLC kwisiseko esomisiweyo) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API;Isinyi esisebenza ngokugqithisileyo |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-API (CAS: 242478-38-2)liyeza le-antimuscarinic elisetyenziselwa ukunyanga i-bladder esebenzayo kakhulu ebangela iimpawu zokuphindaphinda, ukukhawuleza, okanye ukungazinzi.Yonayi-M3 ye-muscarinic receptor antagonist eyaphuhliswa kwaye yaqaliswa kunyango lwe-bladder overactive (pollakiuria) eYurophu.Ii-receptors ze-M3 ziye zabandakanyeka kwi-neurally evoked smooth muscle contractions of the bladder, kunye ne-M2 receptors baye bakrokrelwa ukuba badlala indima ngenxa yokulawula kwabo kwi-detrusor muscle.Isetyenziselwa unyango lwe-Urological.Yonai-antispasmodic yomchamo yeklasi ye-antimuscarinic.