I-3-Aminopiperidine-2,6-Dione Hydrochloride CAS 24666-56-6;2686-86-4 Ubunyulu > 99.0% iLenalidomide Intermediate Factory

Inkcazelo emfutshane:

I-3-Aminopiperidine-2,6-Dione Hydrochloride

CAS: 24666-56-6

I-CAS ehambelanayo: 2686-86-4;25181-50-4

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Umgubo weCrystalline oMhlophe

Umbindi weLenalidomide (CAS: 191732-72-6)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical ngumenzi ohamba phambili we-3-Aminopiperidine-2,6-Dione Hydrochloride (CAS: 24666-56-6; 2686-86-4) enomgangatho ophezulu, ophakathi kwePomalidomide (CAS: 19171-19-8).I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga i-3-Aminopiperidine-2,6-Dione Hydrochloride, Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza I-3-Aminopiperidine-2,6-Dione Hydrochloride
Izithethantonye I-3-Aminopiperidine-2,6-Dione HCl;3-Amino-2,6-Piperidinedione Hydrochloride;2,6-Dioxopiperidine-3-Ammonium Chloride
Inombolo yeCAS 24666-56-6
CAS ezinxulumene 2686-86-4;25181-50-4
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C5H9ClN2O2
Ubunzima beMolekyuli 164.59
Indawo yokunyibilika 120℃
I-COA kunye ne-MSDS Iyafumaneka
Imvelaphi Shanghai, China
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo weCrystalline oMhlophe
Ubunyulu / Indlela yokuHlalutya >99.0% (HPLC)
Ukufuma (KF) <0.50%
Ilahleko ekomisweni <0.50%
Intsalela kwi-Ignition <0.20%
Ukungcola ngokupheleleyo <1.00%
I-Infrared Spectrum Iyahambelana noLwakhiwo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Umbindi weLenalidomide (CAS: 191732-72-6)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

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Isicelo:

I-3-Aminopiperidine-2,6-Dione Hydrochloride (CAS: 24666-56-6; 2686-86-4) iphakathi ukulungiselela iLenalidomide (CAS: 191732-72-6).ILenalidomide luhlobo lwamachiza e-antitumor aphuhliswe ziinkampani zaseMelika zebhayoloji ezixuba amayeza.Inemisebenzi emininzi efana ne-anti-tumor, i-immune regulation kunye ne-anti-angiogenesis.Inokuthintela ukukhuselwa kwee-cytokines ezivuthayo, kunye nokwandisa imfihlo ye-peripheral blood mononuclear anti-inflammatory cytokines.Inokuthintela ukukhula kweeseli ze-myeloma ezininzi zezigulane kunye neseli ye-MM1S.Izifundo ezimbini zeklinikhi ezilawulwa ngokungenamkhethe eziphindwe kabini ze-placebo zivavanya ukhuseleko kunye nesiphumo sonyango se-lenalidomide esetyenziselwa i-myeloma eninzi.Iziphumo zophando lweklinikhi zakutsha nje zibonisa ukuba i-lenalidomide ayinayo kuphela impembelelo yonyango ekunyangeni i-MDS kunye ne-MM, kodwa nakwi-myeloma, i-leukemia, i-metastatic renal cell carcinoma, i-tumor eqinile, i-idiopathic generalized amyloidosis kunye ne-systemic bone marrow fibrosis isifo esinomongo ongavuthwanga.NgoDisemba 2005, i-US Food and Drug Administration (FDA) ivume i-lenalidomide ukuba isetyenziswe kunyango lwe-myelodysplastic syndrome (MDS).

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