1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity>99.0% (HPLC) Umfanekiso obonakalayo

I-1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-enye CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity>99.0% (HPLC)

Inkcazelo emfutshane:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-enye

CAS: 27387-31-1

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Umgubo weCrystalline oMhlophe okanye oMhlophe

Iziphakathi ze-Ondansetron Hydrochloride Dihydrate

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Please contact: alvin@ruifuchem.com

AbaPhathi abanxulumeneyo:

AbaPhakathi abanxulumeneyo be-Ondansetron Hydrochloride Dihydrate

1,3-Cyclohexanedione	I-CAS 504-02-9
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-enye	I-CAS 27387-31-1
Ondansetron Hydrochloride Dihydrate	I-CAS 103639-04-9

Iipropati zeMichiza:

Igama leMchiza	1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-enye
Izithethantonye	I-1,2,3,4-Tetrahydro-9-Methylcarbazol-4-enye;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole
Ubume beStokhwe	Ikhona evenkileni
Ukungcola	Ondansetron USP Related Compound C;Ondansetron EP Ukungcola C;I-Ondansetron Hydrochloride Dihydrate Ukungcola C
Inombolo yeCAS	27387-31-1
Ifomula yeemolekyuli	C13H13NO
Ubunzima beMolekyuli	199.25 g/mol
Indawo yokunyibilika	199.0 ukuya 203.0℃
Ukuxinana	1.21±0.10 g/cm3
I-COA kunye ne-MSDS	Iyafumaneka
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Mhlophe ukuya kuMhlophe oMhlophe wePowder	Iyahambelana
Indawo yokunyibilika	199.0 ukuya 203.0℃	200.0 ukuba 202.0℃
Ukungacoceki Okukodwa	<0.50%	Iyahambelana
Ukungcola ngokupheleleyo	<1.00%	Iyahambelana
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)	99.65%
I-1 H NMR Spectrum	Iyahambelana neSakhiwo	Iyahambelana
Ukuqukumbela	Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwisitya esivaliweyo.Gcina kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.

Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.

Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.

Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.

MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.

Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.

Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.

Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.

27387-31-1 - Umngcipheko kunye noKhuseleko:

Iikhowudi zoMngcipheko
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
R52/53 - Inobungozi kwizinto eziphilayo zasemanzini, inokubangela iziphumo ezibi zexesha elide kwindawo ehlala emanzini.
I-R25 - Inetyhefu xa iginyiwe
Inkcazelo yoKhuseleko
S22 - Musa ukuphefumla uthuli.
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
I-S61-Kuphephe ukukhululwa kokusingqongileyo.Jonga kwimiyalelo ekhethekileyo / kumaphepha edatha yokhuseleko.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
Ii-ID ze-UN UN 2811 6.1 / PGIII

27387-31-1 - Isicelo:

I-1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-enye (i-CAS: 27387-31-1) isetyenziswe njengendawo ephakathi kwe-Ondansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Uphuhliso lwenkampani yeGlaxo yaseUnited Kingdom, ngo-1990 eFransi, kwimarike yaseUnited Kingdom.Imveliso yi-serotonin ekhethiweyo kakhulu (i-5-HT3) i-receptor antagonist, inokuthintela i-Nausea ebangelwa i-chemotherapy kunye ne-radiotherapy Vomit, enamandla amakhulu kunye nokukhetha okuphezulu, inokulawula amathumbu amancinci kunye ne-CTZ receptors ezibangelwa ukuvuselela i-Vomit.Ifanelekile kunyango lwe-Nausea Vomit ebangelwa yichemotherapy kunye neradiotherapy, kwaye ingasetyenziselwa uthintelo kunye nonyango lwe-Nausea Vomit ebangelwa emva kotyando.

I-Ondansetron, i-granisetron kunye ne-dolasetron ziziyobisi ezintathu ze-antiemetic ezisetyenziswa ngokuqhelekileyo kwiklinikhi, i-ondansetron inamandla, ikhetha kwaye iguqulelwe i-5-hydroxytryptamine (5-HT3) i-blocker ye-receptor ye-Alpha 1, i-Alpha 2, i-beta 1, i-Beta 2 i-adrenergic receptors kunye ne-histamine H1, I-h2 i-receptor inempembelelo encinci, kwaye ayinayo impembelelo echasayo kwi-H receptor, i-central and peripheral dopaminergic receptors, kwaye inokuthintela i-Nausea kunye ne-Vomit ebangelwa yi-chemotherapy kunye ne-radiotherapy.Xa kuthelekiswa ne-metoclopramide, Impembelelo ye-antiemetic yayinamandla kwaye kwakungekho ukuphendula kwe-extrapyramidal.I-Cisplatin, i-cyclophosphamide, i-doxorubicin ebangelwa yi-Vomit inokuvelisa ngokukhawuleza kunye nefuthe elinamandla lokuchasa isicaphucaphu.Ilungele unyango lweziyobisi cytotoxic okubangelwa chemotherapy kunye nonyango radiation INausea Vomit, kodwa nothintelo kunye nonyango lweNausea Vomit ebangelwa lutyando.I-ondansetron isebenza njengesikhululo sokudlulisa phakathi kwemithambo-luvo ye-visceral afferent esebenzayo kwi-gastrointestinal tract kunye ne-Vomit yamaziko kwintambo yomgogodla, ebangela ukunyakaza kwesisu kunye ne-diaphragmatic.Izidakamizwa ze-Chemotherapy kunye nonyango lwe-radiation lunokubangela ukukhululwa kwe-5-HT emathunjini amancinci, kwaye i-Vomit reflex ibangelwa ukuvuselela i-vagus nerve nge-5-HT3 receptor.Le mveliso ibhloka ukwenzeka kwale reflex, ngelixa ivalela iVomit ebangelwa sisenzo esiphakathi.Indlela yokusebenza yayingaziwa ngeNausea Vomit emva kotyando.I-Ondansetron idibene ne-dexamethasone inokunyusa umphumo we-antiemetic.