CAS 274901-16-5 Purity ≥99.0% (HPLC) API
AbaPhakathi abaNxulumene noBonelelo loMvelisi:
CAS: 274901-16-5
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| Izithethantonye | LAF-237 |
| Inombolo yeCAS | 274901-16-5 |
| Inombolo yeCAT | RF-API30 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
| Ifomula yeemolekyuli | I-C17H25N3O2 |
| Ubunzima beMolekyuli | 303.4 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo weCrystalline oMhlophe |
| Ukuchongwa | I-IR, i-HPLC: Kufuneka ihambelane noMgangatho weReferensi |
| Ujikelezo oluKhethekileyo lwe-Optical | -82.0 ° ukuya -92.0 ° |
| Indawo yokunyibilika | 148.0 ~ 152.0℃ |
| Ilahleko ekomisweni | ≤0.50% |
| Intsalela kwi-Ignition | ≤0.10% |
| Iintsimbi ezinzima | ≤20ppm |
| Isulphate | ≤0.02% |
| I-Chloride | ≤0.05% |
| Ukungacoceki kweChiral | R-Isomer Ukungcola ≤0.50% |
| Izinyibilikisi ezishiyekileyo | |
| Acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| Isopropyl Utywala | ≤5000ppm |
| Ukungcola Okunxulumeneyo | Nge-HPLC |
| Ukungcola A | ≤0.15% |
| Ukungcola B | ≤0.15% |
| Ukungcola C | ≤0.20% |
| Okunye Ukungcola Okukodwa | ≤0.10% |
| Ukungcola ngokupheleleyo | ≤1.00% |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | API, Type 2 Diabetes Mellitus (T2DM) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-API (i-CAS: 274901-16-5) enomgangatho ophezulu.API (CAS: 274901-16-5)i-agent yomlomo ye-anti-hyperglycemic (i-anti-diabetic drug) ye-dipeptidyl peptidase-4 (DPP-4) inhibitor yeklasi entsha yamachiza.Yaphuhliswa nguNovartis (Novartis) Pharmaceutical Co., Ltd, yenye inhibitor elawulwa ngomlomo ye-Dipeptidyl peptidase-IV.Kwi-2008, ivunyiwe ukuthengiswa kwi-European Union yonyango lwe-2 yeswekile.I-API (i-CAS: i-274901-16-5) inqanda ukungasebenzi kwe-GLP-1 kunye ne-GIP nge-DPP-4, ivumela i-GLP-1 kunye ne-GIP ukuba ikwazi ukukhupha i-insulin kwiiseli ze-beta kunye nokucinezela ukukhutshwa kweglucagon ngamaseli e-alpha. iziqithi zeLangerhans kwi-pancreas.I-API (i-CAS: i-274901-16-5) ibonakaliswe ukunciphisa i-hyperglycemia kwi-type 2 yesifo sikashukela.
