Indacaterol Maleate Intermediate CAS 312753-53-0 5,6-Diethyl-2,3-Dihydro-1H-Inden-2-Amine Hydrochloride
Unikezelo lwezoRhwebo lwe-Indacaterol Maleate (CAS: 753498-25-8) abaPhakathi abaNxulumeneyo:
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS: 312753-53-0
I-8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS: 100331-89-3
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone CAS: 173140-90-4
| Igama leMchiza | I-5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride |
| Izithethantonye | Indacaterol Maleate Intermediate |
| Inombolo yeCAS | 312753-53-0 |
| Inombolo yeCAT | RF-PI125 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
| Ifomula yeemolekyuli | I-C13H20ClN |
| Ubunzima beMolekyuli | 225.76 |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo oMhlophe ukuya koMhlophe |
| Ubunyulu / Indlela yokuHlalutya | ≥98.0% (HPLC) |
| Ilahleko ekomisweni | ≤0.50% |
| Ukungacoceki komntu | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Intsalela kwi-Ignition | ≤0.50% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-Indacaterol Maleate (CAS: 753498-25-8) Phakathi |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Indacaterol Maleate (CAS: 753498-25-8) yinto entsha, i-ultra-long-acting, iqala ngokukhawuleza i-β (2) -adrenoceptor agonist kunye ne-bronchodilator.Isetyenziselwa unyango lwezifo ezingapheliyo ze-pulmonary (COPD) kunye ne-asthma.I-Arhente ye-European Medicines Agency (EMA) ivume i-indacaterol njengechiza kwi-2009 phantsi kwegama lokuthengisa i-Onbrez ngelixa e-United States i-Food and Drug Administration ivume phantsi kwegama lokuthengisa i-Arcapta kwi-2011. Ichiza lenziwa njengefom yetyuwa ye-malate.Kwakhona, i-indacaterol yi-molecule ye-chiral;nangona kunjalo, kuphela i-R-enantiomer ecocekileyo isasazwa.Kufuneka ithathwe kanye kuphela ngosuku, ngokungafaniyo nabakhuphisana nabo kwi-formoterol kunye ne-salmeterol.
