ILapatinib Ditosylate Monohydrate CAS 388082-78-8 Ubunyulu > 99.0% (HPLC)

Inkcazelo emfutshane:

Igama leKhemikhali: Lapatinib Ditosylate Monohydrate

CAS: 388082-78-8

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Mthubi oMthubi ukuya koMthubi wePowder oyikristale

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

AbaPhakathi beLapatinib:

Isiseko seLapatinib	I-CAS 231277-92-2
ILapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
Isodium methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
I-2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
I-6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Iipropati zeMichiza:

Igama leMchiza	ILapatinib Ditosylate Monohydrate
Izithethantonye	N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Inombolo yeCAS	388082-78-8
Ubume beStokhwe	Ikhona evenkileni
Ifomula yeemolekyuli	C29H26ClFN4O4S·2(C7H8O3S)·H2O
Ubunzima beMolekyuli	943.48
I-COA kunye ne-MSDS	Iyafumaneka
Imvelaphi	Shanghai, China
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMthubi oMthubi ukuya koMthubi
Ubunyulu / Indlela yokuHlalutya	≥99.0% (HPLC)
Indawo yokunyibilika	240.0 ~ 242.0℃
Ukufuma (KF)	1.9~2.4%
Ukungacoceki Okukodwa	≤0.50%
Ukungcola ngokupheleleyo	≤1.00%
Iintsimbi ezinzima (njenge Pb)	≤20ppm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	API;Kunyango lwezigulane ezinomhlaza webele

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

388082-78-8 - Isicelo:

I-Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) yityuwa ye-ditosylateI-CAS 231277-92-2, i-synthetic, i-quinazoline esebenzayo ngomlomo kunye nomsebenzi onokuthi ube ne-antineoplastic.Ibuyisela umva i-phosphorylation ye-epidermal growth factor receptor (EGFR), i-ErbB2, kunye ne-Erk-1 kunye ne-2 kunye ne-AKT kinases;ikwathintela amanqanaba eprotheyini ye-cyclin D kwimigca yeseli yethumba lomntu kunye ne-xenografts.I-EGFR kunye ne-ErbB2 ziye zabandakanyeka ekukhuleni kweentlobo ezahlukeneyo ze-tumor.Yasungulwa kunyango lwe-HER2 ye-metastatic ephezulu okanye ye-metastatic (ErbB2) yomhlaza webele kubasetyhini abafumene unyango lwangaphambili.Ichiza lafunyanwa laza laphuhliswa yi-GlaxoSmithKline.