Cyproheptadine Hydrochloride Sesquihydrate CAS 41354-29-4 Assay 98.5 ~ 100.5%

Inkcazelo emfutshane:

Cyproheptadine Hydrochloride Sesquihydrate

CAS: 41354-29-4

Uvavanyo: 98.5 ~ 100.5% (Ibalwe kwi-Anhydrous Basis)

Imbonakalo: Umgubo weCrystalline oMhlophe ukuya kuMthubi

Qhagamshelana: UGqr. Alvin Huang

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E-Mail: alvin@ruifuchem.com


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Iimveliso ezinxulumeneyo

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Inkcazo:

I-Ruifu Chemical ngumenzi ohamba phambili weCyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga iCyproheptadine Hydrochloride Sesquihydrate,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza Cyproheptadine Hydrochloride Sesquihydrate
Izithethantonye 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine Hydrochloride Sesquihydrate
Ubume beStokhwe Kwi-Stock, iMveliso yoRhwebo
Inombolo yeCAS 41354-29-4
CAS ezinxulumene 969-33-5 & 129-03-3
Ifomula yeemolekyuli C21H21N·HCl·11/2H2O
Ubunzima beMolekyuli 350.88 g/mol
Indawo yokunyibilika 165℃(dec.)(lit.)
Ukunyibilika kwamanzi Ayinyibiliki ngokupheleleyo emanzini
Ukunyibilika Inyibilika kakhulu kwiMethanol.Inyibilika kwiChloroform.Inyibilika kancinane kwi-Ethanol.Ayinyibiliki kwi-Ether
I-COA kunye ne-MSDS Iyafumaneka
Isampulu Iyafumaneka
Imvelaphi Shanghai, China
Uphawu Ruifu Chemical

Iinkcukacha:

Izinto ImiGangatho yokuHlola Iziphumo
Imbonakalo Umgubo weCrystalline oMhlophe ukuya koMthubi Iyahambelana
Ukuchongwa A. I-Infrared Spectrum kufuneka ihambelane Iyahambelana
B. Kufuneka ihambelane Iyahambelana
Ubunyulu beChromatographic Kufuneka Uvisisane Iyahambelana
Isivavanyi 98.5 ~ 100.5% (Ibalwe kwi-Anhydrous Basics) 99.62%
Amanzi nguKarl Fischer 7.0~9.0% 8.2%
Intsalela kwi-Ignition ≤0.10% 0.08%
Ubumuncu ≤0.15ml ≤0.13ml
Iintsimbi ezinzima ≤10ppm 8ppm
I-Infrared Spectrum Iyahambelana neSakhiwo Iyahambelana
Ukuqukumbela Le mveliso ngokuhlolwa ihambelana nomgangatho we-USP35
Beka ubomi kwishelufa Iminyaka emi-2 ukuba igcinwe ngokufanelekileyo

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
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41354-29-4 - USP35 Umgangatho:

Cyproheptadine Hydrochloride
C21H21N·HCl · 1½H2O 350.88
I-Piperidine, i-4-(5H-dibenzo[a,d] cyclohepten-5-ylidene) -1-methyl-, i-hydrochloride, i-sesquihydrate.
I-4-(5H-Dibenzo [a,d] cyclohepten-5-ylidene) -1-methylpiperidine hydrochloride sesquihydrate [41354-29-4].
I-Anhydrous 323.87 [969-33-5].
I-Cyproheptadine Hydrochloride iqulethe ngaphantsi kweepesenti ze-98.5 kwaye ingabi ngaphezu kwe-100.5 ipesenti ye-C21H21N·HCl, ibalwa ngesiseko se-anhydrous.
Ukupakishwa kunye nokugcinwa- Gcina kwizikhongozeli ezivalwe kakuhle.
Imigangatho yezalathiso ye-USP <11>-
USP Cyproheptadine Hydrochloride RS
Isazisi-
A: I-Infrared Absorption <197K>.
B: Ukufunxwa kwe-Ultraviolet <197U>-
Isisombululo: 16 µg ngemL.
Phakathi: utywala.
I-Absorptivities kwi-286 nm ayifani ngaphezu kwe-3.0%.
C: Dissolve 100 mg yeCyproheptadine Hydrochloride kwi-10 mL ye-methanol.Beka i-1 drop yesisombululo kwiphepha lokucoca, yome, kwaye ujonge phantsi kokukhanya kwe-UV ye-UV emfutshane: i-fluorescence eluhlaza okwesibhakabhaka iyabonwa.
I-Acidity- Dissolve 1.0 g ye-Cyproheptadine Hydrochloride kwi-25 mL ye-methanol, yongeza i-methyl ebomvu ye-TS, kunye ne-titrate nge-0.10 N i-sodium hydroxide: akukho ngaphezu kwe-0.15 mL efunekayo (0.05% njenge-HCl).
Amanzi, Indlela I <921>: phakathi kwe-7.0% kunye ne-9.0%.
Intsalela ekutshisweni <281>: hayi ngaphezulu kwe-0.1%.
Iintsimbi ezinzima, Indlela II <231>: 0.003%.
I-Assay-Dissolve malunga ne-650 mg ye-Cyproheptadine Hydrochloride, ilinganiswe ngokuchanekileyo, kwi-50 mL ye-glacial acetic acid, ukufudumeza ukunyibilika.Ukupholisa, yongeza i-10 mL ye-mercuric acetate TS, i-0.5 mL ye-acetic anhydride, kunye ne-1 drop of crystal violet TS, kunye ne-titrate nge-0.1 N perchloric acid VS ukuya ekupheleni kohlaza.Yenza isigqibo esingenanto, kwaye wenze naluphi na ulungiso oluyimfuneko.I-mL nganye ye-0.1 N perchloric acid ilingana ne-32.39 mg ye-C21H21N·HCl.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

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41354-29-4 - Umngcipheko kunye noKhuseleko:

Iimpawu zeHazard Xn - Ziyingozi
Iikhowudi zoMngcipheko
I-R22 - Iyingozi xa iginyiwe
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
Ii-ID ze-UN UN 2811 6.1/PG 3
WGK eJamani 3
RTECS TM7050000
Ikhowudi yeHS 2933399011
Udidi lweengozi 6.1
Ukupakisha Iqela III
Ubuthi be-LD50 ngomlomo kwiimpuku: 74.2 mg/kg (Loux)

41354-29-4 - Isicelo:

I-Cyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4) luhlobo lwe-pipecolic antihistamines, inokukhuphisana ne-histamine ekhutshwe kwintlangano ye-H1 receptor kwiiseli ezisebenzayo, ngaloo ndlela inokuthintela ukuqala kwe-allergies, kwaye ikhulule i-histamine- i-spasm eyenziwe kunye nemiphumo yokudibanisa, le mveliso ine-H1 eqinile ye-receptor antagonism, i-anti-histamine effect yayo inamandla kune-chlorpheniramine, i-promethazine.Kukho i-anti-serotonin epholileyo ukuya kwephakathi kunye nemiphumo ye-anticholinergic.Ukongezelela, kukho umphumo wokuvuselela ukutya, kunye nokuzuza ubunzima emva kwexesha elithile.
Clinically Cyproheptadine hydrochloride sesquihydrate isetyenziswa ikakhulu urticaria acute and chronic (ingakumbi urticaria ebandayo), papular urticaria, angioedema, allergic eczema, contact dermatitis, allergy ukutya, aleji iziyobisi, rhinitis allergic, hay fever, conjunctivitis allergic kunye migraine, allergic conjunctivitis kunye migraine.Inempembelelo ethile yonyango kwi-asthma ye-bronchial.Isenokusetyenziswa kunyango lwe-adjuvant ye-Cushing's syndrome kunye ne-acromegaly.Isenokusetyenziswa kwakhona njengento yokwandisa umdla kwi-neurotic phobias.Kukho iingxelo zonyango lwe-acanthosis nigricans kunye nokuthintela i-necrotizing pyoderma.
Umsebenzi kunye nosetyenziso lweCyproheptadine Hydrochloride Sesquihydrate (CAS: 41354-29-4)
1. I-Cyproheptadine Hydrochloride yonyango lwe-urticaria, ulusu oluxubileyo kunye ne-rhinitis ye-allergic.
2. I-Cyproheptadine Hydrochloride iyeza elitsha kwiklasi ye-anticoagulant kunye ne-anti-allergies.Ingasetyenziselwa ukuguquguquka komzimba okufana ne-urticaria, i-eczema, i-allergic kunye ne-contact dermatitis kunye ne-pruritus.I-urticaria, i-eczema, i-allergic kunye ne-contact dermatitis, i-pruritus, i-rhinitis, i-migraine kunye ne-asthma ye-bronchial.Ikwasetyenziselwa isifo sikaCushing kunye ne-acromegaly.
3. I-Cyproheptadine Hydrochloride iyiyeza elichasayo elichasana nesenzo se-histamine emzimbeni kwimithambo yegazi kunye ne-bronchial smooth muscle, ngaloo ndlela isusa iimpawu ze-allergies.I-Cyproheptadine hydrochloride isetyenziselwa ukuguquguquka okufana ne-urticaria, eczema, i-allergic kunye ne-contact dermatitis kunye nolusu olurhawuzelayo.

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