I-Dabigatran Etexilate Mesylate CAS 872728-81-9 Ubunyulu > 99.0% (HPLC) Antithrombotic
I-Ruifu Chemical ngumenzi ohamba phambili weDabigatran Etexilate Mesylate (Pradaxa Mesylate; BIBR 1048MS) (CAS: 872728-81-9) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga iDabigatran Etexilate Mesylate,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Dabigatran Etexilate Mesylate |
| Izithethantonye | Pradaxa Mesylate;I-Dabigatran Etexilate Methanesulfonate;I-BIBR 1048MS;N-[[2-[[[4-[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-Methyl-1H-Benzimidazol-5-yl]carbonyl]-N-2-Pyridinyl -β-Alanine Ethyl Ester Methanesulfonate |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 872728-81-9 |
| CAS ezinxulumene | 211915-06-9 Isiseko sasimahla |
| Ifomula yeemolekyuli | I-C35H45N7O8S |
| Ubunzima beMolekyuli | 723.85 g/mol |
| Indawo yokunyibilika | >125℃ |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo oMhlophe ukuya koMthubi oKhanyayo | Iyahambelana |
| Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.9% |
| Ukungacoceki Okukodwa | <0.10% | <0.10% |
| Ukungcola ngokupheleleyo | <0.50% | 0.10% |
| Ilahleko ekomisweni | <0.50% | <0.50% |
| Intsalela kwi-Ignition | <0.20% | <0.20% |
| I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
| Beka ubomi kwishelufa | Iminyaka emibini ukuba igcinwe ngokufanelekileyo | |
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I-Dabigatran Etexilate Mesylate (i-Pradaxa Mesylate; i-BIBR 1048MS) (i-CAS: i-872728-81-9) yenye ikliniki ye-thrombin inhibitor echanekileyo kunye nohlobo olutsha lwe-anticoagulant yomlomo.Indlela yokusebenza kwayo kukuthintela ukubunjwa kwe-fibrin ngokhuphiswano olubuyiselwayo kunye nolunamandla lokuzibophelela kwindawo ethile yokubopha i-fibrin ye-thrombin, ngaloo ndlela inqanda ukubunjwa kwe-thrombus.
I-Dabigatran Etexilate Mesylate (i-Pradaxa Mesylate; i-BIBR 1048MS) (i-CAS: i-872728-81-9) yikliniki ngqo ye-thrombin inhibitor kunye nohlobo olutsha lwe-anticoagulant yomlomo.Indlela yokusebenza kwayo kukuthintela ukubunjwa kwe-thrombus ngokuvimbela ukubunjwa kwe-fibrin ngokubuyisela ukuguqulwa kunye nokukhuphisana ngokunamandla kunye ne-fibrin-specific binding site ye-thrombin.I-Dabigatran Etexilate Mesylate yinto yeziyobisi ze-hematological;iziyobisi anticoagulant;ingasetyenziselwa ukunciphisa umngcipheko we-stroke kunye ne-systemic embolism kwizigulane ezine-non-valvular atrial fibrillation;I-Dabigatran Etexilate Mesylate yinto entsha yokwenziwa kwe-thrombin inhibitor, i-prodrug ye-dabigatran, i-non-peptide thrombin inhibitor.
I-Dabigatran Etexilate Mesylate yi-prodrug ye-Dabigatran eyenziwa yi-metabolized emzimbeni kwaye iguqulelwe kwi-Dabigatran esebenzayo.Xa kuthelekiswa ne-Warfarin, i-Dabigatran Etexilate Mesylate ayifuni ukujongwa rhoqo komsebenzi we-coagulation kunye nohlengahlengiso lwedosi ngexesha lonyango, kwaye kukho ukusebenzisana okumbalwa phakathi kwamachiza kwaye akuchatshazelwa kukutya, ngaloo ndlela kuphuculwe ukuthotyelwa kwamayeza ezigulane.
