I-Enzalutamide CAS 915087-33-1 Ubunyulu > 99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Enzalutamide (i-CAS: 915087-33-1) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga i-Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
| Igama leMchiza | Enzalutamide |
| Izithethantonye | MDV-3100;MDV 3100;4- [3-[4-Cyano-3-(Trifluoromethyl)) phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
| Ubume beStokhwe | KwiStokhwe, Umthamo weMveliso 50 kgs ngenyanga |
| Inombolo yeCAS | 915087-33-1 |
| Ifomula yeemolekyuli | I-C21H16F4N4O2S |
| Ubunzima beMolekyuli | 464.44 g/mol |
| Indawo yokunyibilika | 198.0 ~ 200.0℃ |
| Ukuxinana | 1.49 |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo oqinileyo oMhlophe ukuya koMhlophe | Iyahambelana |
| Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) | 99.57% |
| Amanzi nguKarl Fischer | <0.50% | 0.23% |
| Intsalela kwi-Ignition | <0.10% | 0.06% |
| Iintsimbi ezinzima (Pb) | ≤20ppm | <10ppm |
| Izinto ezinxulumeneyo | ||
| Max.Ukungacoceki Okukodwa | <0.50% | <0.50% |
| Ukungcola ngokupheleleyo | <1.00% | 0.43% |
| I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
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UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
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Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
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Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
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Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
I-Enzalutamide (i-CAS: i-915087-33-1) ngumchasi we-androgen-receptor (AR) kunye ne-IC50 ye-36 nM, evimba i-androgens ekubopheni i-androgen receptor kwaye inqande ukuhanjiswa kwenyukliya kunye ne-co-activator recruitment ye-ligand-receptor complex.I-Enzalutamide nayo ibonakaliswe ukuba yenza i-tumor cell apoptosis, kwaye ayinayo umsebenzi we-agonist.I-Enzalutamide ngumgqatswa kunyango lomhlaza wedlala lesinyi.I-Enzalutamide, isizukulwana sesibini se-androgen receptor (AR) isibonakaliso se-inhibitor.Iyakwazi ukuthintela ukubophelela kwe-androgens kwi-AR, i-AR i-nuclear translocation, kunye nentlangano ye-AR kunye ne-DNA.Ngo-Agasti 2012, i-FDA yavuma i-Enzalutamide, ithengiswa yi-Medivation kunye ne-Astellas Pharma yase-US kunyango lwe-metastatic castration-resistant prostate cancer (CRPC), ngokukodwa ezo zigulana ezazifumene i-Docetaxel ngaphambili.
