ICaspofungin Acetate Cancidas CAS 179463-17-3 API Factory High Purity
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leKhemikhali: I-Caspofungin Acetate
CAS: 179463-17-3
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | I-Caspofungin Acetate |
Izithethantonye | iiCancidas;MK-0991 Acetate;L-743872 Acetate |
Inombolo yeCAS | 179463-17-3 |
Inombolo yeCAT | RF-API58 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | C52H88N10O15·2C2H4O2 |
Ubunzima beMolekyuli | 1213.42 |
Indawo yokunyibilika | >197℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye ophantse wamhlophe |
Ukuchongwa kwe-IR | I-IR: I-Spectrum yesampula yoVavanyo kufuneka ihambelane ne-Caspofungin Acetate Reference Standard |
Ukuchongwa kwe-HPLC | I-HPLC: Ixesha lokugcinwa kwencopho yomgaqo efunyenwe kwisisombululo sovavanyo kufuneka ihambelane naleyo ifunyenwe kwisisombululo esisemgangathweni, njengovavanyo kwi-Assay. |
Ukucaca kunye nombala | Isisombululo kufuneka sicace kwaye singenambala |
Ukujikeleziswa okuthe ngqo | -102.0 ° ~ -108.0 ° |
pH | 5.0~7.0 |
Amanzi | ≤10.0% |
Izinto ezinxulumeneyo I | (Kwisiseko esisimahla seAnhydrous kunye neAcetic Acid) |
Ukungcola A | ≤0.10% |
Ukungcola B | ≤0.10% |
Ukungcola D | ≤0.30% |
Ukungcola E | ≤0.10% |
Ukungcola Okungachazwanga F | ≤0.10% |
Ukungcola Okungachazwanga G | ≤0.10% |
I-Pneumocandin B0 | ≤0.10% |
Ukungcola Okungaziwayo Ongatshatanga | ≤0.10% |
Ukungcola ngokupheleleyo | ≤1.0% |
Izinto ezinxulumeneyo II | ≤0.10% |
Izinyibilikisi ezishiyekileyo | |
I-Ethyl Acetate | ≤5000ppm |
I-Ethanol | ≤5000ppm |
IMethanol | ≤5000ppm |
Acetonitrile | ≤410ppm |
Tetrahydrofuran | ≤720ppm |
Umxholo weAcetic Acid | 9.0% ~ 11.0% (Ibalwe kwisiseko esingenamanzi) |
Ethylendiamine | ≤0.10% |
Intsalela kwi-Ignition | ≤0.10% |
Iintsimbi ezinzima (njenge Pb) | ≤10ppm |
Indlela yoVavanyo / yoHlahlelo | 97.0% ~ 102.0% (Kwisiseko seAnhydrous kunye neSolvent Free) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Caspofungin Acetate (i-CAS: 179463-17-3) i-lipopeptide ye-antifungal drug.I-Caspofungin acetate yenaliti yavunywa ekuqaleni yi-FDA e-USA, kunye ne-EMEA eYurophu, ngo-2001. I-Caspofungin Acetate yi-soluble yamanzi, i-stable, i-aza-substituted semisynthetic derivative ye-Pneumocandin B, imveliso yokuvundiswa kwe-fungus Zalerion arboricola.I-lipopeptide caspofungin, inqanda ukuhlanganiswa kwe-1,3-beta-D-glucans ekhoyo kuphela kwindonga yeeseli zefungal, ezikhokelela kwi-lysis ethile yeeseli ze-pathogenic.Ikhompawundi ine-fungicidal kune-fungistatic, into engaqhelekanga phakathi kwee-antifungal agents.I-Caspofungin ibisebenza kakhulu kune-amphotericin B, i-flucytosine, i-fluconazole kunye ne-itraconazole ngokuchasene neentlobo ze-Candida.