CDI CAS 530-62-1 N,N'-Carbonyldiimidazole Coupling Reagent Purity >98.0% (T) Factory

Inkcazelo emfutshane:

Igama leMichiza: N,N'-Carbonyldiimidazole

Izithethantonye: CDI

CAS: 530-62-1

Ubunyulu: >98.0% (Titration)

Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Ukudibanisa iReagent yePeptides Synthesis

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-N, N'-Carbonyldiimidazole (CDI) (i-CAS: 530-62-1) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-reagents ezikhuselayo kunye ne-coupling reagents.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iCDI,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	N,N'-Carbonyldiimidazole
Izithethantonye	CDI;1,1'-Carbonyldiimidazole;1,1'-Carbonylbis-1H-Imidazole;I-Di-1H-imidazol-1-yl-methanone;1,1'-Carbonylbisimidazole;N,N'-Carbonylbis(imidazole)
Ubume beStokhwe	Kwi-Stock, iMveliso yeMisa
Inombolo yeCAS	530-62-1
Ifomula yeemolekyuli	I-C7H6N4O
Ubunzima beMolekyuli	162.15 g/mol
Indawo yokunyibilika	116.0 ukuya ku-122.0℃(lit.)
Ukuxinana	1.303 g/mL ku-25℃
Gcina Ngaphantsi kweGesi eNgangeni	Gcina Ngaphantsi kweGesi eNgangeni
Inovakalelo	I-Hygroscopic, i-Sensitive ukufuma, uBubushushu
Ukunyibilika kwamanzi	Ayinyibilikiyo emanzini
Ukunyibilika	Inyibilika kwiDimethylformamide
Ugcino Temp.	Indawo epholileyo neyomileyo (2~8℃)
I-COA kunye ne-MSDS	Iyafumaneka
Udidi	Coupling Reagents
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Mhlophe ukuya kuMhlophe-Mhlophe wePowder	Iyahambelana
Indawo yokunyibilika	116.0 ukuba 122.0℃	118.0 ~ 118.5℃
Ilahleko ekomisweni	<0.50%	0.03%
Ubunyulu / Indlela yokuHlalutya	>99.0% (Titration)	99.1%
Ukunyibilika kwi-DMF 50mg/ml	Icacile ukuya kuHazy Kakhulu Kancinci	Iyahambelana
I-Infrared Spectrum	Iyahambelana neSakhiwo	Iyahambelana
Ukuqukumbela	Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile, iikhilogram ezingama-25 emele yentsimbi (40×55) ifoyile yealuminiyam igungxula initrogen ukupakisha, okanye ngokwemfuno yomthengi.
Imeko yoGcino:I-Hygroscopic, i-varian sensitive.Le mveliso kufuneka igcinwe kwindawo epholileyo, enomoya, eyomileyo, kude nomlilo, umthombo wokushisa, ukushisa okuphezulu, umswakama, amanzi, ukukhanya, i-insolation.Ngexesha lokuthutha, nceda uyiphathe ngononophelo ukukhusela iphakheji ekuqhekekeni.Gcina le mveliso ivaliwe kakuhle.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Indlela yoVavanyo:

N,N'-Carbonyldiimidazole (CDI)
Umgangatho womgangatho
Inyathelo 1 Isampulu
Le mveliso ilula ukubola xa ibonakaliswe kumswakama, indawo yesampuli kufuneka ibekwe kwindawo epholileyo neyomileyo, isampuli (kubandakanywa nesampuli yokulinganisa).Izixhobo zombane kufuneka zicoceke kwaye zome kwaye zithathwe iisampulu kwangoko.
2. Iipropati
Thatha isampulu ye-5g kwibhotile yeglasi engenambala, ecacileyo, uyitywine, uyibeke phantsi kokukhanya kwendalo, kwaye uyijonge ngokukhawuleza ngeliso lenyama.
Inyathelo lesi-3: Ubunyulu
Ukuchaneka kobunzima besampulu 0.2g ~ 0.3g kwibhotile yeconical.Yongeza i-glacial acetic acid 35ml, yongeza i-acetic anhydride 1ml, isalathisi se-crystal violet i-2 yehla.Ithontsi yafakwa i-0.1mol / L perchloric acid de imfusa yanyamalala, kwaye uvavanyo olungenanto lwenziwa.
Ifomula yokubala:
FX(V-V0)×8.1075
Ubunyulu= ------------------------ ×100%
M×1000
Apho:
F: I-Perchloric acid titration isisombululo sokulungisa i-concentration factor
V: Umthamo wesampulu yetitration
V0: umthamo wetitration engenanto
I-8.1075: I-1ml nganye ye-titrant esetyenzisiweyo ilingana ne-8.1075mg yesampuli
M: Ubunzima besampulu (g)
4. Indawo yokunyibilika
3.1 Izixhobo kunye nezixhobo a) Isixhobo sokunyibilikisa
b) I-Capillary
3.2 Inkqubo
Ukuqalisa, isixhobo sokunyibilika ukulungisa ingxaki, kuya kuvavanywa.Ngokukhawuleza ukupakisha isampuli nge-capillary (kuba isampuli kwaye kulula ukubola), cinezela
Indlela yokusebenza yesixhobo sendawo yokunyibilika.
5. Ugcino: Gcina kwindawo epholileyo neyomileyo kude nokukhanya
6. Ixesha lokuhlolwa kwakhona: unyaka omnye

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.

Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.

Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.

Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.

MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.

Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.

Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.

Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.

530-62-1 - Umngcipheko kunye noKhuseleko:

Iikhowudi zoMngcipheko
I-R22 - Iyingozi xa iginyiwe
I-R34 - Ibangela ukutsha
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
R40 - Ubungqina obuncinci besiphumo somhlaza
R36/38 - Iyacaphukisa emehlweni kunye nolusu.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
I-S37/39 - Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso
S27 - Khulula ngoko nangoko zonke iimpahla ezingcolisekileyo.
S36/37 -Nxiba iimpahla ezifanelekileyo zokukhusela kunye neeglavu.
Ii-ID ze-UN UN 3263 8/PG 2
WGK eJamani 2
FLUKA BRAND F IIKHOWUDI 10-21
I-TSCA T
Ikhowudi yeHS 2933290090
Inqaku Lengozi Inobungozi/IyokuNcisa/Inobuzaza bokufuma
Udidi 8 lweengozi
Ukupakisha Iqela III
Ubuthi be-LD50 ngomlomo kuMvundla: 1071 mg / kg

530-62-1 -Isicelo:

I-N, N'-Carbonyldiimidazole (CDI) (i-CAS: 530-62-1), i-peptide coupling reagent, isetyenziswe kwi-synthesis ye-peptides.I-CDI sisixhobo sokudibanisa i-peptide, sisetyenziswa ekudibaneni kweepeptides.Isabela ngokukhawuleza kunye ne-carboxylic acids yenze i-acyl imidazoles;impendulo elandelayo kunye nee-amines ukwenza ii-amides zihamba kakuhle.
I-agent ye-condensation ebalulekileyo yokwenza i-nucleoside triphosphates, i-peptide-triphosphate kunye ne-triphosphate;kubalulekile phakathi ukudibanisa i-acylimidazole.
Njenge-agent ye-condensation ye-synthesis ye-triphosphonucleosides, i-peptides kunye ne-esters;Kwaye yinto ephakathi ebalulekileyo kwi-synthesis ye-acyl imidazole kunye ne-pyridoxamide, ukhuseleko lweqela le-biochemical synthetic kunye ne-protein peptide chain connection.
I-Peptide coupling reagent CDI isebenza njenge-reagent yokudibanisa kwaye isetyenziselwa ukudibanisa i-amino acids ukuze kulungiswe i-peptide kwi-organic synthesis.Ikwasetyenziswa ekulungiseleleni i-beta-keto sulfones, sulfoxides kunye ne-beta-enamino acid derivatives.Isetyenziselwa ukuguqula i-alcohols kunye ne-amines zibe yi-carbamates, i-esters, kunye ne-urea.Ibandakanyeka ekulungiseleleni i-formylized imidazole ngokusabela nge-asidi ye-formic.Ngapha koko, isetyenziswa ekudibaneni kweekhompawundi ze dipolar polyamides.Ukongeza koku, kuthathwa njengento elinganayo ye-phosgene kwaye isetyenziselwa ukulungiselela i-asymmetric bis alkyl carbonate.
I-CDI yi-derivative ye-imidazole, kunye nesakhiwo sayo se-imidazole sine-P bond evaliweyo enkulu, kwaye kukho iperi eyedwa yee-electron kwi-sp2 orbital apho i-athomu ye-nitrogen enye ayidityaniswanga.Oku kugqiba ukuba i-CDI inomsebenzi oqinileyo wokuphendula imichiza, inokusabela nge-ammonia, utywala, i-asidi kunye namanye amaqela asebenzayo, kwaye idibanise iikhompawundi ezininzi ekunzima ukuzifumana ngeendlela zemichiza jikelele.Isetyenziswa ngokubanzi njenge-enzyme kunye ne-protein binder, i-intermediate kwi-synthesis ye-antibiotics, ngakumbi njenge-agent edibeneyo ye-synthetic polypeptide compounds.
I-CDI yi-zero ubude obudibanisa i-reagent esetyenziselwa ukudibanisa ii-amine eziphambili kumaqela asebenzayo e-carboxyllic acid.I-CDI isabela kunye ne-carboxylate ion (COO-) yeeprotheyini okanye ezinye iikhompawundi eziphilayo, zenza i-intermediate esebenzayo ethi emva koko iphendule kunye neqela le-amino (-NH2).Le reagent inokusetyenziselwa ukudibanisa iiproteni ezimbini, kwaye iqhele ukusetyenziswa kwiprotein immobilization kwinkxaso eqinileyo okanye inwebu.Ngokufanelekileyo, i-CDI ingasetyenziswa kuzo zombini iinkqubo ezinamanzi kunye ne-organic solvent.
Isetyenziswa njengeyeza zinambuzane kunye ne-pharmaceutical intermediate.