I-Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% Umfanekiso oMgangatho oPhezulu

I-Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% Umgangatho ophezulu

Inkcazelo emfutshane:

Igama leKhemikhali: Cetrorelix Acetate

CAS: 130143-01-0

Imbonakalo: Umgubo oMhlophe

I-Peptide Purity (HPLC): ≥98.0%

I-Synthetic Antagonist ye-GnRH Receptor

GMP Peptides, API, Umgangatho ophezulu

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili weCetrorelix Acetate (CAS: 130143-01-0) enomgangatho ophezulu.I-Cetrorelix Acetate ngumchasi we-gonadotropin-releasing hormone (GnRH).I-Ruifu Chemical ibonelela ngothotho lweepeptide ze-GMP.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iCetrorelix Acetate,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	Cetrorelix Acetate
Izithethantonye	N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- I-D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate
Ulandelelwano	Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH2
Inombolo yeCAS	130143-01-0
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kwiiKilogram
Ifomula yeemolekyuli	I-C70H92N17O14
Ubunzima beMolekyuli	1551.16
Ugcino Temp.	Indawo epholileyo neyomileyo (-20℃).Isikhenkcisi
Beka ubomi kwishelufa	> Iminyaka emi-2 ukuba igcinwe ngokufanelekileyo
Udidi	GMP Peptides
Uxwebhu	I-COA, i-MS, i-HPLC, i-NMR, i-MSDS, njl.
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe
I-Peptide Purity (nge-HPLC)	≥98.0% (ngoManyano lweNdawo)
Umxholo wePeptide	≥80.0% (nge-%N)
Ukwakhiwa kweAmino Acid	I-10% ye-Theetical
Umxholo weAcetate	≤10.0% (nge-HPLC)
Umxholo weTFA	≤1.0%
Ukungacoceki Okukodwa	≤1.0% (nge-HPLC)
Isiqulatho samanzi (uKarl Fischer)	≤8.0%
Isivavanyi	95.0 ~ 105.0% (Nge-Anhydrous, i-Acetic-Free)
MS	Iyahambelana
Umgangatho woVavanyo	Umgangatho woShishino
IiMfuno zokuThumela	Iingxowa zomkhenkce, iingxowa zeDesiccant
Imvelaphi yeMveliso	Ukwenziwa
Ingqalelo	Kuphela kuPhando, hayi usetyenziso lwabantu
Ukusetyenziswa	I-Synthetic Antagonist ye-GnRH Receptor

Ukupakishwa kunye noGcino:

Umqulu:Iplastiki yeplastiki (enikezelwe ukupakishwa kwepeptide) okanye iglasi yeglasi, ubungakanani ngokwemfuno yeenkcukacha zomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Cetrorelix Acetate (i-CAS 130143-01-0) ngumchasi we-gonadotropin-releasing hormone (GnRH) ethengiswa ngokukodwa phantsi kwegama le-brand Cetrotide.I-synthetic decapeptide, isetyenziswa ekuncediseni ukuvelisa ukuthintela ukukhutshwa kwehomoni ye-luteinizing yangaphambi kwexesha.Ichiza lisebenza ngokuthintela isenzo se-GnRH kwi-pituitary, ngaloo ndlela icinezela ngokukhawuleza imveliso kunye nesenzo sehomoni ye-luteinizing (LH) kunye ne-follicle-stimulating hormone (FSH).I-Cetrorelix Acetate yenziwe ngeentlobo ngeentlobo zee-amino acids ezingezizo ezendalo ezithintela i-ovulation kwangethuba kwiimvavanyo zeklinikhi, ezikhokelela ekuqokeleleni i-ovulation kunye noncedo lonyango lobuchwephesha bokuzala kwizigulane ezilawulwa yi-ovarian stimulation.
Isalathisi i-Cetrorelix Acetate yi-hormone eyenziweyo evimba iziphumo ze-gonadotropin-releasing hormone (GnRH).Kwiteknoloji encedisiweyo yokuzala, kwizigulane ezinokulawulwa kwe-ovarian stimulation, ukukhusela i-ovulation ngaphambi kwexesha.
Isenzo se-Pharmacological Cetrorelix Acetate ngumchasi we-gonadotropin-releasing hormone (GnRH).I-GnRH inokubophelela kwi-membrane receptors yeeseli zepituitary.I-Cetrorelix acetate ibophelela ngokukhuphisanayo kwezi zamkeli ezine-GnRH engapheliyo, ngaloo ndlela i-dose-inhibite ngokuxhomekeke kwi-secretion ye-luteinizing hormone (LH) kunye ne-follicle stimulating hormone (FSH) yi-adenohypophysis.Isiphumo sokuthintela senziwa ngokukhawuleza emva kokulawulwa kwe-cetrorelix acetate, kwaye umphumo wokuthintela unokugcinwa ngonyango oluqhubekayo.kubafazi, i-Cetrorelix Acetate inokulibazisa i-LH ephezulu, ngaloo ndlela ilibazisa i-ovulation.Kubasetyhini abafumana uvuselelo lwe-ovarian, ixesha lesenzo lalixhomekeke kumthamo.I-dose eyodwa ye-cetrorelix 3mg yayiqikelelwa ukuba ibe nefuthe lokuthintela ubuncinane ubuncinane beentsuku ze-4, kunye nefuthe elithintelayo malunga ne-70% kwiSuku 4. Ukulawulwa ngokuphindaphindiweyo kwe-cetrorelix acetate 0.25mg nganye iiyure ze-24 kunokugcina umphumo wayo.I-hormone-antagonizing effect ye-Cetrorelix Acetate yatshintshwa ngokupheleleyo ekupheleni kwonyango kwizilwanyana kunye nabantu.
Umsebenzi we-Biological Cetrorelix Acetate ngumchasi onamandla we-GnRH receptor enexabiso le-IC50 le-1.21 nM.
Ithagethi IC50: 1.21 nM GnRH.