Cisatracurium Besylate CAS 96946-42-8 Assay 95.0% ~ 102.0% API Factory High Quality
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leKhemikhali: Cisatracurium Besylate
CAS: 96946-42-8
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | Cisatracurium Besylate |
Inombolo yeCAS | 96946-42-8 |
Inombolo yeCAT | RF-API13 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C53H72N2O12.2C6H5O3S |
Ubunzima beMolekyuli | 1243.49 |
Indawo yokunyibilika | 90.0~93.0℃ |
Imeko yokuthumela ngenqanawa | Phantsi koBubushushu be-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye ophantse ube mhlophe, awunavumba, uneHygroscopic kancinane |
Ukunyibilika | Inyibilika ngokukhululekileyo kwi-dichloromethane, i-acetonitrile, i-soluble kancinane emanzini |
Ukujikeleziswa okuthe ngqo | -35.0 ° ukuya -45.0 ° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid) |
Ukuchongwa | Nyibilikisa nge-dilute hydrochoric acid, i-dropwise dilute bismuth potassium iodide TS, imvula emthubi iya kuveliswa |
Ukuchongwa | 1. I-HPLC;2. I-IR |
Isivavanyi | 95.0 ~ 102.0% (C65H82N2O18S2 kwisiseko esomileyo) |
pH | 3.5 ukuya ku-5.0 |
Ukucaca kunye nombala wesisombululo | Kufuneka icace kwaye ingabi naMbala |
Ilahleko ekomisweni | ≤2.0% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤20ppm |
Trans-Trans-Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Ii-Mono-quaternaries | ≤1.50% |
Nakuphi na Ukungacoceki komntu | ≤1.50% |
Ukungcola ngokupheleleyo | ≤5.0% |
Isomer ye-Optical SS-Isomer | ≤1.50% |
Isomer ye-Optical RS- Isomer | ≤1.00% |
Sulfate | ≤50ppm |
I-Ethyl | ≤0.50% |
I-acetone | ≤0.50% |
IMethanol | ≤0.3% |
Dichloromethane | ≤0.06% |
Acetonitrile | ≤0.041% |
I-methylbenzene | ≤0.089% |
Intsalela yezinyibilikisi iAcetonitrile | ≤410ppm |
Umgangatho woVavanyo | I-China Pharmacopoeia (CP) |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Cisatracurium Besylate (CAS 96946-42-8) yifom ye-benzene sulfonate yetyuwa ye-atracurium.Luhlobo lwe-artificially synthetic non-depolarizing izihlunu zokuphumza kunye nendima yayo efana ne-tubocurarine.Umthamo wonyango awuchaphazeli intliziyo, isibindi kunye nomsebenzi wezintso.Kananjalo ayinayo ipropati yokuqokelela.Isenokwenza ukuba kukhululwe i-histamine xa isetyenziswa kumthamo omkhulu.Ukuphumla kwe-muscle okanye ukulawulwa kokuphefumula okufunekayo kuqhaqho, xa kuthelekiswa neyeza zangoku zeklinikhi ezinkulu ze-muscle-relaxing anesthetic, i-cisatracurium besylate ayinayo i-metabolized ngesibindi okanye izintso, kwaye ine-cardiovascular stability;umphumo walo wokuphumla kwemisipha ngamaxesha e-3 anamandla njenge-atracurium ngaphandle kwemiphumo emibi ye-cardiovascular.I-Cisatracurium besylate isetyenziswa kakhulu kwi-anesthesia jikelele, kwaye ingasetyenziselwa ngokubanzi kwi-intubation, ukuphatha isibindi kunye nokungasebenzi kakuhle kwezintso, ezisetyenziselwa utyando lwe-cardiovascular and asebekhulile kunye nezigulane zabantwana.Xa kuthelekiswa ne-atracurium, le mveliso ayinayo imiphumo emibi exhomekeke kumthamo wokukhutshwa kwe-histamine;nangona kunjalo, into engalunganga kukuba izigulane ezinesifo sesibindi kunye nezintso kufuneka zilawule ngokuqaphela.Ukusukela ngo-1996 okokuqala ngqa xa eli chiza lingena kwimarike e-UK, amazwe angaphandle aye alisebenzisa ngokuthe ngcembe ukuba athathe indawo ye-vecuronium kunye ne-atracurium njengeyona ndlela iphambili yokuphumza izihlunu.