(-)-Corey Lactone 4-Phenylbenzoate Alcohol BPCOD CAS 31752-99-5 Ucoceko >99.0% (HPLC) Prostaglandin Intermediate Factory
I-Ruifu Chemical Supply Prostaglandin Intermediates:
(-)-Corey Lactone Diol CAS 32233-40-2
(+)-Corey Lactone Diol CAS 76704-05-7
(±)-Corey Lactone Diol CAS 54423-47-1
(-)-Corey Lactone Benzoate CAS 39746-00-4
(-)-Corey Lactone 4-Phenylbenzoate Utywala;BPCOD CAS 31752-99-5
Igama leMchiza | (-)-Corey Lactone 4-Phenylbenzoate Utywala |
Izithethantonye | (-)-Corey Lactone 4-Phenylbenzoate;(-)-Corey lactone 4-PBP;I-BPOD;(3aα,4α,5β,6aα)-(-)-Hexahydro-4-(Hydroxymethyl)-2-oxo-2H-Cyclopenta[b]furan-5-yl 1,1′-Biphenyl-4-Carboxylate;(3aR,4S,5R,6aS)-Hexahydro-4-Hydroxymethyl-5-(4-Phenylbenzoyloxy)cyclopenta[b]furan-2-enye |
Inombolo yeCAS | 31752-99-5 |
Inombolo yeCAT | RF-PI1998 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C21H20O5 |
Ubunzima beMolekyuli | 352.38 |
Ukuxinana | 1.30±0.10 g/cm3 |
Ukunyibilika kwamanzi | H2O: Ayinyibiliki |
Ukunyibilika | Inyibilika kwiChloroform kunye neMethanol |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe ukuya koMthubi okanye umgubo weCrystalline |
Ukuchongwa yi-HPLC | Ixesha logcino lwencopho enkulu kwikhromatogram yesampulu ihambelana naleyo yomgangatho njengoko ufunyenwe kwi-isomer. |
Indawo yokunyibilika | 128.0 ~ 134.0℃ |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Isiqulatho samanzi (KF) | <0.50% |
Intsalela kwi-Ignition | <0.20% |
Ukujikeleziswa okuthe ngqo [α]20/D | -85.0 ° ukuya -89.0 ° (C=1.0, CHCl3) |
(+) Isomere | <0.10% |
Ukungacoceki okuphezulu okukodwa | <0.50% |
Ukungcola ngokupheleleyo | <1.00% |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Proton NMR Spectrum | Iyahambelana neSakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Prostaglandin Intermediates;ILatanoprost ePhakathi |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
(-) -I-Corey Lactone 4-Phenylbenzoate Utywala (i-CAS: 31752-99-5) ingundoqo ephakathi kwi-synthesis ye-prostaglandins.Ibhloko yokwakha ehlukeneyo ye-prostaglandins.Ibhloko yokwakha ye-agent ye-antiglaucoma enamandla kunye ne-analog ye-PGF2α.Isetyenziswe kwi-Prostaglandin Derivatives;Isetyenziswe njengeProstaglandin Series Intermediates.I-Prostaglandins luhlobo lwezinto ezibalulekileyo ezisebenzayo ze-physiological endogenous kunye nabalamli ababalulekileyo bezinto ezahlukeneyo zomzimba.iinkqubo, kunye nomsebenzi ophezulu we-pharmacological.Ngokweklinikhi, iiProstaglandins zonke zenziwe ngokufanelekileyo.Ibhloko yokwakha ehlukeneyo ye-prostaglandins.Ibhloko yokwakha ye-agent ye-antiglaucoma enamandla kunye ne-analog ye-PGF2α.(-)-Corey Lactone 4-Phenylbenzoate Utywala yinto ephakathi kweLatanoprost (CAS: 130209-82-4).I-Latanoprost yi-analogue ye-prostaglandin F2a.Yiprostanoid ekhethiweyo ye-FP receptor agonist ekukholelwa ukuba iyanciphisa uxinzelelo lwe-intraocular (IOP) ngokunyusa ukuphuma kwe-humor aqueous.Isetyenziselwa ukunyanga iintlobo ezithile zeglaucoma(i-open-angle glaucoma ocular hypertension).Ikwasetyenziselwa ukunyanga imeko ebizwa ngokuba yi-hypertension yeliso.ILatanoprost isetyenziselwa ukonyusa ukuphuma kwendalo kolwelo (ukuhlekisa okumanzi) ukusuka ngaphakathi kwiliso ukuya egazini.Kubonakala ngathi kusebenza ngokunyusa ukuphuma kolwelo olusuka kwiliso.Oku kwehlisa uxinzelelo kwiliso.