Cyano-Irbesartan CAS 138401-24-8 Ubunyulu >98.0% (HPLC) Irbesartan Intermediate Factory

Inkcazelo emfutshane:

Igama leKhemikhali: Cyano-Irbesartan

CAS: 138401-24-8

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Mhlophe ukuya Phantse kuMhlophe uPowder ukuya kwiCrystal

Umbindi we-Irbesartan (CAS: 138402-11-6)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

IRuifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
I-TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1

Iipropati zeMichiza:

Igama leMchiza	Cyano-Irbesartan
Izithethantonye	iCyanoIrbesartan;Ukungacoceki kwe-Irbesartan Cyano;I-Irbesartan Hydrocarbon;Ukungcola kwe-Irbesartan 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-enye;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl] -2-carbonitrile
Inombolo yeCAS	138401-24-8
Inombolo yeCAT	RF-PI1892
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C25H27N3O
Ubunzima beMolekyuli	385.51
Ukuxinana	1.15
Ukunyibilika (Nyibilika ngaphakathi)	IMethanol
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya Phantse uMhlophe uPowder ukuya kwiCrystal
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)
Ubunyulu	>97.0% (NgeNitrojeni iyonke)
Indawo yokunyibilika	91.0 ukuba 95.0℃
Ilahleko ekomisweni	<1.00%
Ukungacoceki Okukodwa	<1.00%
Iintsimbi ezinzima	<20ppm
I-Infrared Spectrum	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Phakathi / Ukungacoceki kwe-Irbesartan (CAS: 138402-11-6)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Cyano-Irbesartan (i-CAS: 138401-24-8) iphakathi okanye ukungcola kwe-Irbesartan (CAS: 138402-11-6).I-Irbesartan yi-angiotensin II (i-Angiotensin II, i-Ang II) inhibitor ye-receptor.I-Angiotensin II receptors zihlukaniswe zibe zimbini iintlobo: i-AT1 kunye ne-AT2.I-Irbesartan ivala ngokukhetha i-AT1 receptor ye-AnglI.Inokuthintela ukuguqulwa kwe-Ang kwi-Ang, inokuchasa ngokukodwa i-angiotensin-converting enzyme 1 receptor (AT1).Isiphumo esichasayo kwi-AT1 ngama-8500 amaxesha e-AT2.Inokuthintela ngokukhethekileyo ukubopha i-Ang kunye ne-AT1 i-receptor nge-Inhibit vasoconstriction kunye nokukhululwa kwe-aldosterone, okubangelwa umphumo we-hypotensive.Le mveliso ayivimbeli i-angiotensin yokuguqula i-enzyme (i-ACE), i-renin, enye i-receptors ye-hormone, kwaye ayivimbeli iziteshi ze-ion ezinxulumene nokulawulwa kwengcinezelo yegazi kunye nebhalansi ye-sodium.I-Irbesartan inokunciphisa ukulungiswa kwakhona kombane kwi-myocardium, ngaloo ndlela inciphisa izinga lokufa kwezigulana ezinoxinzelelo lwegazi.Okwangoku lelona chiza lisebenzayo kunyango loxinzelelo lwegazi kunye nezifo zentliziyo.