I-α-Cyclodextrin (α-CD) i-CAS 10016-20-3 i-Pharmaceutical Excipients
I-Ruifu Chemical ngumenzi ohamba phambili we-α-Cyclodextrin (α-CD) (i-CAS: 10016-20-3) enomgangatho ophezulu.I-Ruifu Chemical ibonelela nge-pharma grade cyclodextrins, ii-excipients zamayeza.I-Ruifu Chemical inokubonelela ngeenkonzo zehlabathi, ezincinci kunye nezixa ezininzi ezikhoyo.Thenga i-α-Cyclodextrin,Please contact: alvin@ruifuchem.com
Igama leMchiza | α-Cyclodextrin |
Izithethantonye | α-CD;C;Alfadex;ialpha-Dextrin;α-Dextrin;Cyclohexapentylose;Cavamax W6;I-Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;Cyclomaltohexaose;Cyclohexaamylose |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 10016-20-3 |
Ifomula yeemolekyuli | C |
Ubunzima beMolekyuli | g/mol |
Indawo yokunyibilika | >278℃(dec.) (lit.) |
Indawo yokubilisa | ℃ |
Indawo yokuflasha | ℃ |
Ukuxinana | |
Refractive Index n20/D | 1 |
Inovakalelo | Hygroscopic.Ukungeva kuMoya, ukuKhanya, uBuvane ukufuma |
Ukunyibilika kwamanzi | Inyibilika emanzini |
Ukunyibilika | Inyibilika ngaphakathi |
Uzinzo | Izinzile.Ukutsha.Ayihambelani ne-Agents eqinile ye-Oxidizing. |
I-COA kunye ne-MSDS | Iyafumaneka |
Isampuli yasimahla | Iyafumaneka |
Imvelaphi | Shanghai, China |
Udidi | AbaXhasi bamayeza;Izongezo zokutya |
Uphawu | Ruifu Chemical |
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | Mhlophe okanye Phantse uMhlophe Amorphous okanye Crystalline Powder | Iyahambelana |
Ukunyibilika | Inyibilika ngokukhululekileyo kuManzi nakwiPropylene Glycol, ayiNyibiliki kwiEthanol nakwiMethylene Chloride | Iyahambelana |
i-ldentification HPLC | Ixesha lokugcinwa kwencopho enkulu yesisombululo sesampuli sihambelana nesisombululo esiqhelekileyo. | Iyahambelana |
Isisombululo soVavanyo lwe-Iodine | Imvula etyheli-bumdaka iyasekwa | Iyahambelana |
Isivavanyi | 98.0% ~ 101.0% (Ibalwe kwisiseko esomileyo) | 100.0% |
Ujikelezo oluKhethekileyo [a]20/D | +147.0 ° ukuya +152.0°(C=1 nge-H2O) (Calcd. kwi-Anh. Substance) | +148,2 ° |
Ukucaca kunye nombala wesisombululo | I-10mg / ml Isisombululo saManzi sicacile kwaye singenambala | Iyahambelana |
Umda wezinto ezifunxa ukukhanya | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | Iyahambelana |
Ukumiselwa kwamanzi | ≤11.0% | 9.9% |
Intsalela kwi-Ignition | ≤0.10% | 0.07% |
Iintsimbi ezinzima | ≤5ppm | <5ppm |
Ityuwa yeArsenic (njenge) | ≤1.3ppm | <1.3ppm |
Ukunciphisa Iswekile | ≤0.20% | 0.16% |
Izinto ezinxulumeneyo | ||
Betadex Cyclodextrin | ≤0.25% | N/D |
IGamma Cyclodextrin | ≤0.25% | N/D |
Ezinye Izinto Eziyeleleneyo | ≤0.50% | N/D |
pH | 5.0~8.0 | 6.2 |
Uvavanyo lweMicrobiological | ||
Ubalo olupheleleyo lweAerobic Microbial | ≤1000cfu/g | 30cfu/g |
IiMngundo zizonke kunye neYeasts zibala | ≤50cfu/g | <50cfu/g |
Escherichia Coli | Ukungabikho | Ukungabikho |
Salmonella | Ukungabikho | Ukungabikho |
I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
Umgangatho woVavanyo | USP41-NF36 |
Umqulu:0.5kg//bag, 1kg/bag, 2kg/bag,10kg/bag, 25kg/Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
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Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
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Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
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Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko R36 - Iyacaphukisa emehlweni
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
Inkcazo yoKhuseleko S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
WGK eJamani 3
RTECS GU2292000
TSCA Ewe
HS Code 3505100000
I-α-Cyclodextrin (α-CD) (CAS: 10016-20-3)yi-saccharide ye-cyclic engancitshiyo equka iiyunithi ezintandathu ze-glucose ezidityaniswe yi-alpha-1.4 bond.Iveliswa ngesenzo se-cyclodextrin glucosyl transferase kwi-hydrolysed starch syrups.I-cavity ye-alpha-Cyclodextrin ingaphantsi kwe-beta-Cyclodextrin, ngoko isetyenziselwa ukuvumela ukubunjwa kwee-complexes ezifakwe kunye nama-molecule amancinci.Iqondo le-solubility ye-Alpha-Cyclodextrin emanzini yi-14.5 g / 100ml @25 ° C, ngoko ke imeko efuna ukunyibilika okuphezulu kwe-cyclodextrin.
I-Alpha-cyclodextrin isetyenziswa ngokubanzi kumachiza, ukutya, incasa kunye nezithambiso.I-Alpha-cyclodextrin iphinda isetyenziswe ngokubanzi kwintsimi ye-pesticide kunye nokulungelelanisa i-metabolization yesityalo kunye nokwandisa ubuninzi besityalo.Ngokukodwa i-cyclodextrin kunye ne-ramification yayo ephuhliswe yile minyaka, ezinye zazo ziyi-solutizer ebalulekileyo, i-stablizer, i-relever okanye izixhobo zokuncedisa iziyobisi ze-Entericcoated, ezinye zazo zizinto ze-organic synthetical macromolecular stuff.
Ibakala lokutya i-Alpha cyclodextrin ene-6 iiyunithi ze-glucose inomngxuma omncinci womzali we-cyclodextrins.Kuluncedo ekunyibilikeni, ekuzinziseni okanye ekuhambiseni iimolekyuli ezincinci, umz. ubunzima obuphantsi bemolekyuli, i-flavour okanye i-fragrance compounds.Ibakala lokutya i-Alpha cyclodextrin ikwaziswa kwishishini lokutya njenge-fiber entsha ye-soluble dietary eneempawu ezikholisayo.
I-Cyclodextrin inomngxuma phakathi kwesakhiwo sendandatho, kunye ne-athomu ye-oksijini apho -i-CH- ibophelela kwi-glucoside.I-sulfure-aqueous, kunye namaqela e-hydroxyl kwi-2, i-3 kunye ne-6 isikhundla se-glucose yi-hydrophilic.Ingasetyenziselwa ukuntsonkotha ezinye iimolekyuli zibe ziikhompleksi ezidityanisiweyo ngamandla abuthathaka e-van der Waals.Izinto ezininzi zinokufakwa kwi-cyclodextrins, kubandakanywa neegesi ezihloniphekileyo, i-halogens, iidayi, iziqhumiso, amayeza, ukutya, i-pesticides kunye ne-preservatives.Emva kwe-encapsulation, ukuzinza kwayo, ukuguquguquka, ukunyibilika kunye nokusebenza kwakhona kuphuculwe.Impembelelo ekhethekileyo yeCyclodextrin yenza ukuba ibe yinto esetyenziswa ngokubanzi kwi-encapsulation.
1. Ukusetyenziswa kwe-Cyclodextrin kwishishini lamachiza kunokwenza i-encapsulation (encapsulation) kunye neziyobisi, ezinokuthi (1) Iziyobisi ezingazinzanga zizinzile;(2) I-Deliquescence, i-adhesion okanye i-powderization yeziyobisi ezingamanzi;(3) Amachiza angenakunyibilika okanye angaxutywanga anganyibilika (i-solubilized), njl.
2. Ukusetyenziswa kwi-pesticide industry cyclodextrin encapsulation stabilization, ezinye ii-pesticides zingagcinwa kwaye ziphucule ukusebenza kwe-insecticidal.
3. Ukusetyenziswa kwishishini lokutya i-cyclodextrin isetyenziswe kwishishini lokutya, ineempembelelo ezilandelayo: (1) Ukuphelisa kunye nokugubungela iphunga elikhethekileyo;(2) Ukuphuculwa kunye nokuphuculwa kwesakhiwo sezicubu zokutya;(3) ukunciphisa kunye nokususwa kwencasa ekrakra;(4) Isiphumo se-Antioxidant;(5) Ukugcinwa kunye nokulungelelaniswa kwencasa.
4. Ukusetyenziswa kwe-Cyclodextrin kwishishini lemichiza yemihla ngemihla kwimveliso ye-cosmetic nayo ingasetyenziselwa njenge-emulsifier kunye nokuphucula umgangatho.Ikwanayo ne-deodorization (njengokongezwa kwi-halitosis) kunye nemiphumo ye-antiseptic, ingasetyenziselwa ukuxutywa kwamazinyo, ukuveliswa komgubo wezinyo.
5. Ezinye izinto ezisetyenziselwa ukukhuselwa kwendalo zingasetyenziswa njenge-agent yonyango ye-oily sewege.Isisombululo esinamanzi seCyclodextrin sisetyenziselwa ukucoca itanki yeoli, kwaye ulwelo lwenkunkuma lunokufunyanwa kwaye luphathwe ukufumana ioyile yamafutha.
6. Ukusetyenziswa kwe-cyclodextrin kwi-chemistry Cyclodextrin i-reagent ye-chemical reagent.Xa ikhona, ukuqina kwe-fluorescence ye-fluorochrome kuya kwanda kakhulu, ngoko ingasetyenziselwa uhlalutyo lweeprotheni kunye ne-amino acids.Ingasetyenziselwa ukwahlula iikhompawundi ze-organic chain ende, i-racemes, njl.
Ukongeza, i-adsorbent eyenziwe kwiCyclodextrin ingasetyenziselwa i-chromatographic adsorption.
Umsebenzi
1. α-Cyclodextrin Ukwandisa ukuzinza kwezinto: Ukuthintela ukuguquguquka, ukuthintela i-sublimation;I-Anti-oxidation;Ukuthintela ukubola kwe-optothermal;Anti ukubola kweekhemikhali;Yandisa ixesha lokuba semthethweni kwezinto.
2. α-Cyclodextrin Ukwandisa i-solubility yezinto eziphathekayo kunye ne-bioavailability.
3. I-α-Cyclodextrin ngokuqulunqwa kwe-inclusion complex ukuphumeza i-cover esebenzayo ivumba elimnandi.
4. I-α-Cyclodextrin ichiza lolwelo libe kwimeko eqinileyo.
5. α-Cyclodextrin Ukuthintela iziyobisi - ichiza, iziyobisi - ukusebenzisana phakathi kwesongezo.
6. α-Cyclodextrin Nciphisa iziphumo ebezingalindelekanga.
Isicelo
1. I-α-Cyclodextrin isetyenziselwa ukunyusa ukuzinza kwezinto: Ukuthintela ukuguquguquka, ukukhusela i-sublimation;I-Anti-oxidation;
2. I-α-Cyclodextrin isetyenziselwa ukuthintela ukubola kwe-optothermal;Anti ukubola kweekhemikhali;Yandisa ixesha lokuba semthethweni kwezinto.
3. I-α-Cyclodextrin isetyenziselwa ukunyusa i-solubility yezinto eziphathekayo kunye ne-bioavailability.
4. Ngokusekwa kwe-inclusion complex ukuphumeza ivumba elisebenzayo lokugquma.Iyeza elulwelo libe kwimeko eqinileyo.
5. I-α-Cyclodextrin isetyenziselwa ukukhusela iziyobisi - iziyobisi, iziyobisi - ukusebenzisana phakathi kwe-additive.
6. I-α-Cyclodextrin isetyenziselwa ukunciphisa imiphumo emibi.
Amachiza:
1. Ukwandisa ukunyibilika kokufumaneka kwebhayoloji
2. Ukuphucula i-bioavailability
3. Ukulungelelanisa okanye ukulawula ukukhutshwa
4. Ukunciphisa iityhefu
5. Ukuphucula ukuzinza
Izithambiso:
1. Ukulungelelanisa i-encapsulation yeekhompawundi eziguquguqukayo.
2. Ukwandisa ubomi beshelufu yeencasa ezibizayo.
Ukutya:
1.Ukuthintela ukuvela kwezinto eziguqukayo.
2.Ukususa ivumba elibi.
3.Ukuphucula kakhulu iziphumo ze-emulsification
I-α-Cyclodextrin ifunyenwe ukwenza i-complex eqinile kunye namafutha okutya.Ngale ndlela kunciphisa i-bioavailability kunye nokufunxa kwamafutha.Kuyaziwa ngokulawula amanqanaba e-triglyceride kunye ne-leptin kwi-serum.Kwiimodeli zegundane, i-α-Cyclodextrin iboniswa ukuba ibangele i-insulin sensitivity kunye ne-fecal fat excretion.Ngaloo ndlela, i-α-Cyclodextrin ithathwa njengesebenzayo ekunyangeni ukutyeba kunye ne-syndromes ye-metabolic.
Ibandakanyiwe kwi-FDA ye-Inactive Ingredients Database: α-Cyclodextrin (amalungiselelo e-injection);I-β-Cyclodextrin (iipilisi zomlomo, iigels ze-topical);γ-Cyclodextrin (IV injections).Ibandakanyiwe kuLuhlu lwaseKhanada lweZithako ezaMkelweyo ezingezizo zonyango (i-agent yokuzinzisa; i-agent ye-solubilizing);kunye nakwimixube yoxubo lwamayeza oluthethwayo kunye neerectal ezinelayisensi eYurophu, eJapan, nase-USA.