I-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) i-Pharmaceutical Excipients

Inkcazelo emfutshane:

Igama leKhemikhali: Hydroxypropyl-β-Cyclodextrin

Izithethantonye: Cyclodextrin HPB;I-HPBCD;HP-β-CD

CAS: 128446-35-5

Mhlophe okanye Phantse uMhlophe Amorphous okanye Crystalline Powder

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

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Inkcazo:

I-Ruifu Chemical ngumenzi ohamba phambili we-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iHydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza IHydroxypropyl-β-Cyclodextrin
Izithethantonye Cyclodextrin HPB;IHydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl)-beta-Cyclodextrin;i-beta-Hydroxypropylcyclodextrin;HBC;I-HPBCD;HP-β-CD
Ubume beStokhwe Kwi-Stock, iMveliso yoRhwebo
Inombolo yeCAS 128446-35-5
Ifomula yeemolekyuli C63H112O42
Ubunzima beMolekyuli 1541.54 g/mol
Indawo yokunyibilika 262.0~269.0℃
Ukuxinana 1.05
Ujikelezo oluKhethekileyo [a]20/D +120° ukuya +135° (C=1, H2O)
Ukunyibilika kwamanzi Inyibilika emanzini
I-COA kunye ne-MSDS Iyafumaneka
Isampuli yasimahla Iyafumaneka
Imvelaphi Shanghai, China
Uphawu Ruifu Chemical

Iinkcukacha:

Izinto Iinkcukacha Iziphumo
Imbonakalo I-White Powder, Insipid, Innocent Iyahambelana
IR Spectrum Iibhendi zokufunxa okufanayo kunye ne-USP Hydroxypropyl Betadex RS Iyahambelana
pH 5.0~7.5 6.57
Ukucaca kwesisombululo Isisombululo esicacileyo nesingenambala Iyahambelana
Ilahleko ekomisweni ≤10.0% 3.5%
Intsalela kwi-Ignition ≤0.20% 0.09%
Iintsimbi ezinzima ≤20ppm <10ppm
I-Chloride ≤0.05% <0.05%
Ukutshintshwa kweMolar 0.4~1.5 0.63
Ukuqhuba I-10% (w / v) Isisombululo samanzi ≤200μS / cm 154µS/cm
Isidanga soTshintsho 2.8~10.5 5.3
Intsalela Betadex ≤1.50% 0.12%
Ipropylene Glycol ≤2.50% 0.29%
Ipropylene oxide ≤1ppm <1ppm
Nakuphi na Okunye Ukungcola Okukodwa ≤0.25% <0.25%
Isimbuku sobunye ubumdaka ≤1.00% (Ngaphandle kweBetadex kunye nePropylen Glycol) 0.51%
TAMC ≤1000cfu/g 30cfu/g
I-TYMC ≤100cfu/g 10cfu/g
Escherichia Coli Ayifumaneki Iyahambelana
Salmonella Ukungabikho Ukungabikho
Iintsholongwane ze-Endotoxins <10IU/g <10IU/g
Ukuqukumbela Ivavanyiwe kwaye ithobela uMgangatho we-USP35

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

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Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

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Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

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128446-35-5 - Umngcipheko kunye noKhuseleko:

Inkcazelo yoKhuseleko 24/25 - Gwema ukudibana nolusu kunye namehlo.
WGK eJamani 3
RTECS GU2293332
Ikhowudi ye-HS 3505100000

128446-35-5 - Ukusetyenziswa:

I-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (i-CAS: 128446-35-5) isetyenziswe ngokubanzi i-cyclodextrin eguquliweyo, i-lipophilic cavity eyenziwe ngamayunithi e-glucose e-7.Ukunyibilika kweziyobisi emanzini kuphuculwe kakhulu ngokudibanisa ne-HP-β-CD.Ukugquma kwe-Enteric, ukukhutshwa okuzinzileyo, ukuhanjiswa kweziyobisi kwi-buccal kunye ne-transdermal.
I-Hydroxypropyl-β-Cyclodextrin, i-hydroxyalkyl derivative, ifumana isicelo njengesithuthi sokuqulunqa esisetyenziselwa ukunyusa ukunyibilika kwamachiza kwizisombululo zamanzi zokunikezelwa ngempumelelo kwee-agent zonyango kwiinkqubo ze-biological.Ngokuqhelekileyo isetyenziswa njenge-substitute ye-α-, β- kunye ne-γ-Cyclodextrins.

128446-35-5 - Izicelo zoNyango:

IHydroxypropyl betadex iphandwe ngokubanzi kumayeza kwaye ngokuyintloko isetyenziswe njenge-solubilizer ye-hydrophobic molekyuli kulwelo lomlomo, izinto eziqinileyo zomlomo, ii-parenterals, i-inhalers yedosi ecinezelekileyo, i-powder inhalers eyomileyo, kunye ne-topical formulations.Kwakhona kuye kwaboniswa ukuba kusebenze njenge-stabilizer ngexesha lokucubungula kunye nokugcinwa kweefomyula.I-Hydroxypropyl betadex inclusion complexes iye yaxelwa ukuba ibonise iimpawu zomatshini ezahlukileyo kwizinto ezicocekileyo.Inzuzo exeliweyo ye-hydroxypropyl betadex ngaphezu kwe-b-cyclodextrin engafakwanga kukunyibilika kwayo okukhulu kwamanzi.

128446-35-5 - Umsebenzi:

1. I-Solubilization kunye ne-solubilization, yenza iziyobisi ezinganyibilikiyo zinyibilike, ziphucule ukunyibilika kwamacandelo asebenzayo eziyobisi ezinamafutha, kujoliswe ekunikezelweni kweziyobisi kunye nokukhusela ukusebenza kwezithako zeziyobisi.
2. Ukuphucula i-bioavailability yechiza, ukwandisa isiphumo sonyango okanye ukunciphisa umthamo.
3. Lungisa okanye ulawule izinga lokukhululwa kweziyobisi ukunciphisa iziphumo ebezingalindelekanga.
4. Gquma ivumba elibi.

128446-35-5 -Isicelo:

1) Kwintsimi yamayeza,
1. I-Hydroxypropyl Beta Cyclodextrin inokunyusa ukunyibilika kweyeza kunye nokufumaneka kwezinto eziphilayo, kwaye yongeze umphumo omhle kwaye inciphise umthamo.
2. I-HP-β-CD inokulawula okanye ilungelelanise isantya sokusebenza, yehlise ubutyhefu bechiza kwaye yandise uzinzo lwamachiza.
3. I-injection injection solubilizer kunye ne-excipients yeziyobisi ngenxa yomsebenzi ongaphantsi komhlaba kunye nomsebenzi we-hemolytic, akukho ukucaphuka kwemisipha.
4. I-HP-β-CD ayisetyenziselwanga kuphela iziyobisi zomlomo, i-injection, inkqubo yokuhanjiswa kweziyobisi ze-mucosal, inkqubo yokuhanjiswa kweziyobisi ze-transdermal, i-lipotropy ejolise kwi-carrier carrier, kodwa ingasetyenziselwa njengeprotheyini yokukhusela i-protein kunye ne-stabilizer.
5. Ukuphucula iimpawu ze-organoleptic zezinto ezibuhlungu okanye ezingathandekiyo.
2) Kwintsimi yokutya,
1. I-HP-β-CD inokuthintela ukuguquka kwezinto eziguquguqukayo ezigcina ukuzinza kwezondlo zayo, ukulahla iphunga elibi kwaye kunokunyusa kakhulu imiphumo ye-emulsification kunye nokusetyenziswa okudibeneyo kokutya okuxutywayo.
2. I-HP-β-CD inokwenza isigcinakaliso sokuphuma kokutya kancinci, inyuse isiphumo sokuchasana nokubola kunye nokwandisa ixesha leshelufu lokutya.
3) Kwishishini leZithambiso
1. Kwizinto zokuthambisa izinto ezisetyenziswa njenge-stabilizer, emulsifier, solubilizer njl.
2. I-HP-β-CD inokunciphisa ukuvuselela esikhumbeni, kwaye yandise uzinzo lwamacandelo asebenzayo.
3. I-HP-β-CD inokunciphisa okanye igqume ivumba elibi le-nutrition molecular.
4. Thintela ukubunjwa kwezondlo eziguquguqukayo, i-oxidation, ukwandisa ukunyanzeliswa, i-essence, i-perfume e-soluble yamanzi kwaye Gcina iphunga elimnandi likhupha ngokukhawuleza kwaye lihlala lihlala.

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