I-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) i-Pharmaceutical Excipients
I-Ruifu Chemical ngumenzi ohamba phambili we-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iHydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com
Igama leMchiza | IHydroxypropyl-β-Cyclodextrin |
Izithethantonye | Cyclodextrin HPB;IHydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl)-beta-Cyclodextrin;i-beta-Hydroxypropylcyclodextrin;HBC;I-HPBCD;HP-β-CD |
Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
Inombolo yeCAS | 128446-35-5 |
Ifomula yeemolekyuli | C63H112O42 |
Ubunzima beMolekyuli | 1541.54 g/mol |
Indawo yokunyibilika | 262.0~269.0℃ |
Ukuxinana | 1.05 |
Ujikelezo oluKhethekileyo [a]20/D | +120° ukuya +135° (C=1, H2O) |
Ukunyibilika kwamanzi | Inyibilika emanzini |
I-COA kunye ne-MSDS | Iyafumaneka |
Isampuli yasimahla | Iyafumaneka |
Imvelaphi | Shanghai, China |
Uphawu | Ruifu Chemical |
Izinto | Iinkcukacha | Iziphumo |
Imbonakalo | I-White Powder, Insipid, Innocent | Iyahambelana |
IR Spectrum | Iibhendi zokufunxa okufanayo kunye ne-USP Hydroxypropyl Betadex RS | Iyahambelana |
pH | 5.0~7.5 | 6.57 |
Ukucaca kwesisombululo | Isisombululo esicacileyo nesingenambala | Iyahambelana |
Ilahleko ekomisweni | ≤10.0% | 3.5% |
Intsalela kwi-Ignition | ≤0.20% | 0.09% |
Iintsimbi ezinzima | ≤20ppm | <10ppm |
I-Chloride | ≤0.05% | <0.05% |
Ukutshintshwa kweMolar | 0.4~1.5 | 0.63 |
Ukuqhuba | I-10% (w / v) Isisombululo samanzi ≤200μS / cm | 154µS/cm |
Isidanga soTshintsho | 2.8~10.5 | 5.3 |
Intsalela Betadex | ≤1.50% | 0.12% |
Ipropylene Glycol | ≤2.50% | 0.29% |
Ipropylene oxide | ≤1ppm | <1ppm |
Nakuphi na Okunye Ukungcola Okukodwa | ≤0.25% | <0.25% |
Isimbuku sobunye ubumdaka | ≤1.00% (Ngaphandle kweBetadex kunye nePropylen Glycol) | 0.51% |
TAMC | ≤1000cfu/g | 30cfu/g |
I-TYMC | ≤100cfu/g | 10cfu/g |
Escherichia Coli | Ayifumaneki | Iyahambelana |
Salmonella | Ukungabikho | Ukungabikho |
Iintsholongwane ze-Endotoxins | <10IU/g | <10IU/g |
Ukuqukumbela | Ivavanyiwe kwaye ithobela uMgangatho we-USP35 |
Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Inkcazelo yoKhuseleko | 24/25 - Gwema ukudibana nolusu kunye namehlo. |
WGK eJamani | 3 |
RTECS | GU2293332 |
Ikhowudi ye-HS | 3505100000 |
I-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (i-CAS: 128446-35-5) isetyenziswe ngokubanzi i-cyclodextrin eguquliweyo, i-lipophilic cavity eyenziwe ngamayunithi e-glucose e-7.Ukunyibilika kweziyobisi emanzini kuphuculwe kakhulu ngokudibanisa ne-HP-β-CD.Ukugquma kwe-Enteric, ukukhutshwa okuzinzileyo, ukuhanjiswa kweziyobisi kwi-buccal kunye ne-transdermal.
I-Hydroxypropyl-β-Cyclodextrin, i-hydroxyalkyl derivative, ifumana isicelo njengesithuthi sokuqulunqa esisetyenziselwa ukunyusa ukunyibilika kwamachiza kwizisombululo zamanzi zokunikezelwa ngempumelelo kwee-agent zonyango kwiinkqubo ze-biological.Ngokuqhelekileyo isetyenziswa njenge-substitute ye-α-, β- kunye ne-γ-Cyclodextrins.
IHydroxypropyl betadex iphandwe ngokubanzi kumayeza kwaye ngokuyintloko isetyenziswe njenge-solubilizer ye-hydrophobic molekyuli kulwelo lomlomo, izinto eziqinileyo zomlomo, ii-parenterals, i-inhalers yedosi ecinezelekileyo, i-powder inhalers eyomileyo, kunye ne-topical formulations.Kwakhona kuye kwaboniswa ukuba kusebenze njenge-stabilizer ngexesha lokucubungula kunye nokugcinwa kweefomyula.I-Hydroxypropyl betadex inclusion complexes iye yaxelwa ukuba ibonise iimpawu zomatshini ezahlukileyo kwizinto ezicocekileyo.Inzuzo exeliweyo ye-hydroxypropyl betadex ngaphezu kwe-b-cyclodextrin engafakwanga kukunyibilika kwayo okukhulu kwamanzi.
1. I-Solubilization kunye ne-solubilization, yenza iziyobisi ezinganyibilikiyo zinyibilike, ziphucule ukunyibilika kwamacandelo asebenzayo eziyobisi ezinamafutha, kujoliswe ekunikezelweni kweziyobisi kunye nokukhusela ukusebenza kwezithako zeziyobisi.
2. Ukuphucula i-bioavailability yechiza, ukwandisa isiphumo sonyango okanye ukunciphisa umthamo.
3. Lungisa okanye ulawule izinga lokukhululwa kweziyobisi ukunciphisa iziphumo ebezingalindelekanga.
4. Gquma ivumba elibi.
1) Kwintsimi yamayeza,
1. I-Hydroxypropyl Beta Cyclodextrin inokunyusa ukunyibilika kweyeza kunye nokufumaneka kwezinto eziphilayo, kwaye yongeze umphumo omhle kwaye inciphise umthamo.
2. I-HP-β-CD inokulawula okanye ilungelelanise isantya sokusebenza, yehlise ubutyhefu bechiza kwaye yandise uzinzo lwamachiza.
3. I-injection injection solubilizer kunye ne-excipients yeziyobisi ngenxa yomsebenzi ongaphantsi komhlaba kunye nomsebenzi we-hemolytic, akukho ukucaphuka kwemisipha.
4. I-HP-β-CD ayisetyenziselwanga kuphela iziyobisi zomlomo, i-injection, inkqubo yokuhanjiswa kweziyobisi ze-mucosal, inkqubo yokuhanjiswa kweziyobisi ze-transdermal, i-lipotropy ejolise kwi-carrier carrier, kodwa ingasetyenziselwa njengeprotheyini yokukhusela i-protein kunye ne-stabilizer.
5. Ukuphucula iimpawu ze-organoleptic zezinto ezibuhlungu okanye ezingathandekiyo.
2) Kwintsimi yokutya,
1. I-HP-β-CD inokuthintela ukuguquka kwezinto eziguquguqukayo ezigcina ukuzinza kwezondlo zayo, ukulahla iphunga elibi kwaye kunokunyusa kakhulu imiphumo ye-emulsification kunye nokusetyenziswa okudibeneyo kokutya okuxutywayo.
2. I-HP-β-CD inokwenza isigcinakaliso sokuphuma kokutya kancinci, inyuse isiphumo sokuchasana nokubola kunye nokwandisa ixesha leshelufu lokutya.
3) Kwishishini leZithambiso
1. Kwizinto zokuthambisa izinto ezisetyenziswa njenge-stabilizer, emulsifier, solubilizer njl.
2. I-HP-β-CD inokunciphisa ukuvuselela esikhumbeni, kwaye yandise uzinzo lwamacandelo asebenzayo.
3. I-HP-β-CD inokunciphisa okanye igqume ivumba elibi le-nutrition molecular.
4. Thintela ukubunjwa kwezondlo eziguquguqukayo, i-oxidation, ukwandisa ukunyanzeliswa, i-essence, i-perfume e-soluble yamanzi kwaye Gcina iphunga elimnandi likhupha ngokukhawuleza kwaye lihlala lihlala.