I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS 6974-32-9 Assay ≥99.0% (HPLC) Clofarabine Intermediate High Purity
Ubonelelo ngezoRhwebo lweClofarabine oluNxulumene neMiphakathi:
I-Clofarabine CAS: 123318-82-1
I-2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose CAS: 97614-43-2
I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate CAS: 6974-32-9
1,3,5-Tri-O-benzoyl-D-Ribofuranose CAS: 22224-41-5
2,6-Dichloropurine CAS: 5451-40-1
Igama leMchiza | I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate |
Izithethantonye | 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-Ribofuranose |
Inombolo yeCAS | 6974-32-9 |
Inombolo yeCAT | RF-PI222 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C28H24O9 |
Ubunzima beMolekyuli | 504.49 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe |
Indlela yoVavanyo / yoHlahlelo | ≥99.0% (HPLC) |
Indawo yokunyibilika | 126.0 ~ 133.0℃ |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.00% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Pharmaceutical Intermediate yeClofarabine CAS: 123318-82-1 |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate (CAS 6974-32-9) yindawo ephakathi (i-Clofarabine CAS: 123318-82-1).I-Clofarabine (i-CAS: i-123318-82-1) iyinoveli ye-purine nucleoside anticancer drugs iphuhliswe ngempumelelo yi-Top10 biopharmaceutical company ye-United States-Genzyme Corporation kunye namagama orhwebo athi "Clofarabine".NgoDisemba 28, i-2004 i-US yokutya kunye noLawulo lweDrugs (i-FDA) isetyenziswe ngokukhawuleza ukuvunywa kwe-clofarabine kwisicelo kubantwana abane-refractory okanye i-relapsed acute lymphocytic leukemia (YONKE);inokusebenza okugqwesileyo kunyango lwe-leukemia ngokunyamezela kakuhle kwaye akukho ziziphumo ezibi ezingalindelekanga.Inokulawulwa nokuba ifakwe emithanjeni okanye ilawulwe ngomlomo.Eli chiza yimveliso yokuqala evunyiweyo ukuba inikezelwe kunyango lwe-leukemia yabantwana kwiminyaka engaphezu kweshumi.
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