D-Tryptophan CAS 153-94-6 (HD-Trp-OH) Uvavanyo 98.5 ~ 101.0% Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-D-Tryptophan (HD-Trp-OH) (CAS: 153-94-6) kunye nomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-amino acids kunye nezinto eziphuma kuzo.Sinokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, ubungakanani obuncinci kunye nobuninzi obukhoyo.Thenga i-D-Tryptophan,Please contact: alvin@ruifuchem.com
Igama leMchiza | D-Tryptophan |
Izithethantonye | I-HD-Trp-OH;D-(+)-Tryptophan;I-Dextro-(+)-Tryptophan;(R)-Tryptophan;(R)-(+)-2-Amino-3-(3-Indolyl)propionic Acid;(R) -α-Amino-3-Indolepropionic Acid;(R) -α-Aminoindole-3-Propanoic Acid |
Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-35 ngenyanga |
Inombolo yeCAS | 153-94-6 |
Ifomula yeemolekyuli | I-C11H12N2O2 |
Ubunzima beMolekyuli | 204.23 g/mol |
Indawo yokunyibilika | 282.0~285.0℃(dec.)(lit.) |
Ukuxinana | 1.362 |
Ukunyibilika | Inyibilika kancinane emanzini, iNyibilika kancinane kwi-Ethanol (96%) |
Ugcino Temp. | Indawo epholileyo kunye neyomileyo |
I-COA kunye ne-MSDS | Iyafumaneka |
Udidi | I-Amino Acids kunye ne-Derivatives |
Uphawu | Ruifu Chemical |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | Umgubo weCrystalline oMhlophe | Iyahambelana |
Ukujikeleziswa okuthe ngqo [α]20/D | +30.0 ° ukuya +33.0 ° (C=1, H2O) | -33.8 ° |
Imeko yesisombululo | ≥95.0% | Iyahambelana |
Indawo yokunyibilika | 282.0~285.0℃ | 282.8~284.2℃ |
Ikloridi (Cl) | ≤0.020% | <0.020% |
I-Ammonium (NH4) | ≤0.020% | <0.020% |
Isulfate (SO4) | ≤0.020% | <0.020% |
Intsimbi (njenge-Fe) | ≤20ppm | <20ppm |
Iintsimbi ezinzima (njenge Pb) | ≤10ppm | <10ppm |
IArsenic (As2O3) | ≤1ppm | <1ppm |
Ezinye iiAmino Acids | Iyahambelana | Iyahambelana |
Ilahleko ekomisweni | ≤0.20% | 0.15% |
Intsalela kwi-Ignition | ≤0.10% | 0.06% |
Isivavanyi | 98.5%~ 101.0% | 99.6% |
L-Tryptophan | ≤1.00% | 0.79% |
pH | 5.4~6.4 | 6.3 |
IR Spectrum | Ngokungqinelana noMgangatho | Iyahambelana |
Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo |
Iphakheji: Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ubumuncu
Thatha i-1g yale mveliso, yongeza i-50ml yamanzi ukuze uchithe, kwaye ulinganise ngokomthetho (uMthetho Jikelele we-5.4).Ixabiso le-pH kufuneka libe yi-5.4 ~ 6.4.
Ukuhanjiswa kwesisombululo
thatha i-0.5g yale mveliso, yongeza i-2mol / L isisombululo se-hydrochloric acid 20ml ukuchithwa, ngokwe-spectrophotometry ebonakalayo ye-ultraviolet (umgaqo Jikelele we-0401), ukulinganisa ukuhanjiswa kwi-430nm ubude, kungabi ngaphantsi kwe-95.0%.
I-Chloride
Thatha i-0.25g yale mveliso kwaye uyijonge ngokomthetho (umgaqo jikelele we-0801).Xa kuthelekiswa nesisombululo solawulo esenziwe nge-0.02% yesisombululo se-sodium chloride eqhelekileyo, akufanele igxininise ngakumbi ().
Sulfate
Thatha i-l.0g yale mveliso kwaye uyijonge ngokomthetho (umgaqo jikelele we-0802).Xa kuthelekiswa nesisombululo solawulo esenziwe nge-0.02% yesisombululo esiqhelekileyo se-potassium sulfate, akufanele sigxininise ngakumbi ().
Ityuwa ye-ammonium
Thatha i-0.10g yale mveliso kwaye uyijonge ngokomthetho (umgaqo jikelele we-0808).Xa kuthelekiswa nesisombululo solawulo esenziwe nge-0.02% yesisombululo se-ammonium chloride eqhelekileyo, ayiyi kuba nzulu ().
Ezinye iiAmino Acids
Thatha i-0.30g yale mveliso, uyibeke kwi-flask yokulinganisa i-20ml, yongeza i-1 mol / L isisombululo se-hydrochloric acid 1 ml kunye namanzi okuchithwa, uhlambulule ngamanzi kwisikali, ugubungele kakuhle, njengesisombululo sovavanyo;thabatha i-1 ml ngokuchanekileyo, uyibeke kwi-flask yokulinganisa i-200ml, yihlambulule ukulinganisa ngamanzi, ukugubha kakuhle, kwaye uyisebenzise njengesisombululo sokulawula.Thatha i-10mg yokulawula i-tryptophan kunye nolawulo lwe-tyrosine, kwaye uyibeke kwi-flask yokulinganisa i-25ml efanayo, i-1 ml ye-1 mol / L isisombululo se-hydrochloric acid kunye nomlinganiselo ofanelekileyo wamanzi wongezwa ukutshabalalisa isisombululo.Isisombululo sihlanjululwe kwisikali ngamanzi kwaye emva koko saxutywa ukwenza isisombululo esifanelekileyo kwinkqubo.Ngokomaleko obhityileyo wechromatography (General 0502) thatha izisombululo ezithathu zingentla i-2 μL nganye, ngokulandelelanayo, kwi-silica gel G yepleyiti ebhityileyo, ene-n-butanol-glacial acetic acid-water (3:1:1) ukusabalalisa, ukusabalalisa, ukomisa, ukutshiza nge-ninhydrin kwisisombululo se-acetone (1-50), ukushisa kwi-80℃ de iphuzu livela, kwaye ujonge ngokukhawuleza.Isisombululo solawulo kufuneka sibonise indawo ecacileyo, kwaye inkqubo esebenzayo isisombululo kufuneka ibonise amabala amabini ahluke ngokupheleleyo.Ukuba isisombululo sokuvavanya sibonisa amabala okungcola, umbala akufanele ube nzulu (0.5%) kuneyona ndawo iphambili yesisombululo solawulo.
Ilahleko ekomisweni
Thatha le mveliso, yome kwi-105 ℃ kwiiyure ze-3, ukulahlekelwa kwesisindo akuyi kudlula i-0.2% (umgaqo jikelele we-0831).
Intsalela kwi-Ignition
Thatha i-1.0g yale mveliso kwaye uyijonge ngokomthetho (umgaqo jikelele 0841).Intsalela eshiyekileyo ayisayi kudlula i-0.1%.
Ityuwa yentsimbi
Thatha le mveliso i-1.0g emva kokutshisa kunye nomlotha, yongeza i-hydrochloric acid (2ml) kwi-residu, yomise kwindawo yokuhlambela amanzi, uze udibanise i-dilute hydrochloric acid (4ml), uyichithe ekushiseni okuncinci, yongeza amanzi (30ml) kunye ne-ammonium persulfate. (50mg), kwaye ukhangele ngokomthetho (umgaqo Jikelele we-0807), akufanele ube nzulu (0.002%) kunesisombululo solawulo esenziwe ngesisombululo sentsimbi esiqhelekileyo.
Iintsimbi ezinzima
Intsalela eshiywe phantsi kwento yokuthatha intsalela yokutshisa ayiyi kuqulatha ngaphezu kweengxenye ze-10 kwisigidi sentsimbi enzima xa ihlolwe ngumthetho (iMigaqo Jikelele 0821, uMthetho II).
Ityuwa yeArsenic
thatha i-2.0g yale mveliso, yongeza i-5ml ye-hydrochloric acid kunye ne-23ml yamanzi ukunyibilika, khangela ngokomthetho (umthetho Jikelele we-0822 umthetho wokuqala), kufuneka uhambelane nemimiselo (0.0001%).
I-Endotoxin yebhaktiriya
thatha le mveliso, yongeza amanzi ovavanyo lwe-endotoxin yomntu, kunye nobushushu kwi-80 ℃ ukuyinyibilikisa, jonga ngokomthetho (General 1143), i-lg nganye ye-tryptophan equlethe i-endotoxin kufuneka ibe ngaphantsi kwe-50EU.(Yenaliti)
Ukumiselwa komxholo
Thatha le mveliso malunga ne-0.15g, ukulinganisa okuchanekileyo, yongeza i-anhydrous formic acid 3ml enyibilikisiweyo, yongeza i-glacial acetic acid 50ml, ngokwendlela enokuthi i-titration (umgaqo jikelele we-0701), kunye nesisombululo se-hydrochloric acid titration (0.1 mol / L) titration, kunye ne-titration Iziphumo zetitration zalungiswa ngovavanyo olungenanto.I-1 ml nganye yesisombululo se-perchloric acid titration (0.1 mol / L) ihambelana ne-20.42mg ye-C11H12N2O2.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
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Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
R41 - Umngcipheko womonakalo omkhulu emehlweni
I-R37/38 - Iyacaphukisa inkqubo yokuphefumla kunye nolusu.
I-R22 - Iyingozi xa iginyiwe
Inkcazelo yoKhuseleko
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
WGK eJamani 3
RTECS YN6129000
FLUKA BRAND F IIKHOWUDI 8
TSCA Ewe
Ikhowudi yeHS 2922491990
I-Hazard Class Irritant
I-D-Tryptophan (i-HD-Trp-OH) (i-CAS: i-153-94-6) ifom ye-D (ifomu engeyiyo iproteinogenic) ye-amino acid tryptophan.I-amino acids kunye ne-derivatives, esetyenziswa kwi-peptide synthesis, esetyenziswa njenge-organic synthesis ephakathi, i-pharmaceutical intermediate, ukutya / izongezo zokutya, izongezo zesondlo, i-reagent ye-biochemical okanye i-reagent yekhemikhali.
I-Tryptophan yenye ye-amino acids esemgangathweni engama-20, kunye ne-amino acid ebalulekileyo ekutyeni komntu.Ifakwe kwikhowudi yezofuzo eqhelekileyo njenge-codon UGG.i-D-stereoisomer ifumaneka ngamaxesha athile kwiipeptides eziveliswa ngokwendalo (umzekelo, i-marine venom peptide contryphan).Uphawu olwahlukileyo lwesakhiwo se-Tryptophan kukuba iqulethe iqela elisebenzayo le-indole.Yi-amino acid ebalulekileyo njengoko ichazwa ziziphumo zayo zokukhula kwiimpuku.
I-D-Tryptophan amino acid, njengeprotheni engasebenziyo, ineempawu ezikhethekileyo ze-physiological.Ingasetyenziswa njengezinto ezingenazo izondlo, izongezo zokutya, iiarhente zokukhula kwezityalo kwishishini lokutya kunye nezolimo.Kushishino lwamayeza, ikakhulu isetyenziselwa ukuhlanganiswa kweepolypeptides ezahlukeneyo, endaweni yeyeza le-L-Tryptophan peptide yokwandisa isiqingatha sobomi kunye nokunciphisa iziphumo ebezingalindelekanga, kodwa aziyi kuxhathisa kumzimba wangaphambili, kwaye iya kuba yi-enzyme inhibitor ebalulekileyo. .Kwakhona kunokuphucula ukhuselo lomzimba, ukulibaziseka ukusabela komzimba.Uninzi lwe-antibiotiki ye-peptide inokumelana neebhaktheriya zegram-positive, ibhaktheriya ye-Gram-negative kunye nezinye, ezifana ne-Pseudomonas aeruginosa, i-mycobacteria, i-fungi, ibhaktheriya, iintsholongwane kunye neeseli ze-tumor, ezinokuthi zithintele ngcono kwaye zibulale amandla.
I-D-Tryptophan ingasetyenziselwa i-synthetic ye-semi-synthetic antibiotics, apho i-pharmacological idlala indima ebalulekileyo kwikhonkco lecala.I-peptide bond inzima ukuba ibe yi-β-lactam enzyme action, ngaloo ndlela uzinzo oluphezulu, kwaye ine-antibacterial spectrum ebanzi, i-toxicity, i-hypoallergenic, i-absorption esheshayo, i-blood concentrations yeyeza elide elide.