IDantrolene Sodium yetyuwa Hydrate CAS 14663-23-1 API Factory High Quality
Ukubonelela ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leKhemikhali: Dantrolene Sodium yeTyuwa Hydrate
CAS: 14663-23-1
I-Skeletal Muscle Relaxant.I-Calcium Channel Inhibitor
Umgangatho ophezulu we-API, iMveliso yoRhwebo
| Igama leMchiza | Dantrolene Sodium yeTyuwa Hydrate |
| Izithethantonye | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium yeTyuwa Hydrate |
| Inombolo yeCAS | 14663-23-1 |
| Inombolo yeCAT | RF-API78 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
| Ifomula yeemolekyuli | I-C14H11N4NaO5 |
| Ubunzima beMolekyuli | 338.25 |
| Ukunyibilika | Inyibilika kwi-DMSO |
| Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Mthubi-Orenji ukuya kwiOrenji yomgubo weCrystalline.Akukho bungqina bubonakalayo bokungcoliswa zizinto zangaphandle |
| Isazisi A | Ukufunxwa kwe-IR (197K) |
| Isazisi B | Ixesha lokugcinwa kwencopho enkulu kwichromatogram yolungiselelo lovavanyo lihambelana nekhromatogram yolungiselelo oluqhelekileyo, njengoko lufunyenwe kuvavanyo. |
| Isazisi C | Iyahlangabezana neemfuno zovavanyo lomlilo weSodium (191) |
| Isazisi D | Icandelo loku-1: Imvula enkulu, emhlophe, eyikristale yenziwe Icandelo 2: Imvula ayipheli Icandelo lesi-3: Imvula inyibilika ngokupheleleyo Icandelo 4: Akukho mvula yenziweyo |
| Isiqulatho samanzi (nge-KF) | 14.5%~17.0% |
| Ubungakanani beNcam | I-90% ngaphantsi kwe-200um |
| Isivavanyi | I-90.0% ~ 96.0% ye-C14H10N405 kwisiseko se-anhydrous |
| Izinto ezinxulumeneyo | (HPLC, Ummandla%) |
| ICompound eNxulumeneyo A | ≤0.15% |
| Udibaniso olunxulumeneyo B | ≤0.50% |
| iCompandi eNxulumeneyo C | ≤0.30% |
| Izinyibilikisi ezishiyekileyo | |
| I-Ethanol | ≤2000ppm |
| IMethanol | ≤2000ppm |
| I-acetone | ≤2000ppm |
| I-DMF | ≤620ppm |
| Iintsimbi ezinzima | ≤10ppm |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
| Umgangatho woVavanyo | I-United States Pharmacopoeia (USP) |
| Ukusetyenziswa | I-Skeletal Muscle Relaxant.I-Calcium Channel Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Dantrone Sodium Salt Hydrate (i-CAS 14663-23-1), i-molecule encinci inhibitor ye-Ryonodine receptor antagonist kunye ne-Calcium channel inhibitor.I-Dantrolene Sodium Ityuwa i-skeletal muscle relaxant, evimbela i-intracellular Ca 2 + ukukhululwa kwi-sarcoplasmic reticulum.Ukukhutshwa kwe-Ca2 + kwi-reticulum ye-sarcoendoplasmic, ehambelana kakhulu ne-excitation kunye ne-contraction of muscles, ivelisa umphumo wokuphumla kwemisipha ehambelana neDantrolene.I-neurotoxicity evezwe ngumsebenzi we-glutamate ochaziweyo uhambelana nokunyuka okugqithisileyo kumanqanaba e-cytoplasmic Ca2 +, kwaye i-Dantrolene iboniswa ngokufanelekileyo njenge-neuroprotective agent ngokuchasene ne-neurotrasmitter-induced excitotoxicity.I-Dantrolene, iTyuwa yeSodium yi-inhibitor ye-RyR-1 kunye ne-RyR-3.
