IDantrolene Sodium yetyuwa Hydrate CAS 14663-23-1 API Factory High Quality
Ukubonelela ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leKhemikhali: Dantrolene Sodium yeTyuwa Hydrate
CAS: 14663-23-1
I-Skeletal Muscle Relaxant.I-Calcium Channel Inhibitor
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | Dantrolene Sodium yeTyuwa Hydrate |
Izithethantonye | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium yeTyuwa Hydrate |
Inombolo yeCAS | 14663-23-1 |
Inombolo yeCAT | RF-API78 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C14H11N4NaO5 |
Ubunzima beMolekyuli | 338.25 |
Ukunyibilika | Inyibilika kwi-DMSO |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mthubi-Orenji ukuya kwiOrenji yomgubo weCrystalline.Akukho bungqina bubonakalayo bokungcoliswa zizinto zangaphandle |
Isazisi A | Ukufunxwa kwe-IR (197K) |
Isazisi B | Ixesha lokugcinwa kwencopho enkulu kwichromatogram yolungiselelo lovavanyo lihambelana nekhromatogram yolungiselelo oluqhelekileyo, njengoko lufunyenwe kuvavanyo. |
Isazisi C | Iyahlangabezana neemfuno zovavanyo lomlilo weSodium (191) |
Isazisi D | Icandelo loku-1: Imvula enkulu, emhlophe, eyikristale yenziwe Icandelo 2: Imvula ayipheli Icandelo lesi-3: Imvula inyibilika ngokupheleleyo Icandelo 4: Akukho mvula yenziweyo |
Isiqulatho samanzi (nge-KF) | 14.5%~17.0% |
Ubungakanani beNcam | I-90% ngaphantsi kwe-200um |
Isivavanyi | I-90.0% ~ 96.0% ye-C14H10N405 kwisiseko se-anhydrous |
Izinto ezinxulumeneyo | (HPLC, Ummandla%) |
ICompound eNxulumeneyo A | ≤0.15% |
Udibaniso olunxulumeneyo B | ≤0.50% |
iCompandi eNxulumeneyo C | ≤0.30% |
Izinyibilikisi ezishiyekileyo | |
I-Ethanol | ≤2000ppm |
IMethanol | ≤2000ppm |
I-acetone | ≤2000ppm |
I-DMF | ≤620ppm |
Iintsimbi ezinzima | ≤10ppm |
Beka ubomi kwishelufa | iminyaka eyi-2 |
Umgangatho woVavanyo | I-United States Pharmacopoeia (USP) |
Ukusetyenziswa | I-Skeletal Muscle Relaxant.I-Calcium Channel Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
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I-Dantrone Sodium Salt Hydrate (i-CAS 14663-23-1), i-molecule encinci inhibitor ye-Ryonodine receptor antagonist kunye ne-Calcium channel inhibitor.I-Dantrolene Sodium Ityuwa i-skeletal muscle relaxant, evimbela i-intracellular Ca 2 + ukukhululwa kwi-sarcoplasmic reticulum.Ukukhutshwa kwe-Ca2 + kwi-reticulum ye-sarcoendoplasmic, ehambelana kakhulu ne-excitation kunye ne-contraction of muscles, ivelisa umphumo wokuphumla kwemisipha ehambelana neDantrolene.I-neurotoxicity evezwe ngumsebenzi we-glutamate ochaziweyo uhambelana nokunyuka okugqithisileyo kumanqanaba e-cytoplasmic Ca2 +, kwaye i-Dantrolene iboniswa ngokufanelekileyo njenge-neuroprotective agent ngokuchasene ne-neurotrasmitter-induced excitotoxicity.I-Dantrolene, iTyuwa yeSodium yi-inhibitor ye-RyR-1 kunye ne-RyR-3.