I-DCC CAS 538-75-0 Dicyclohexylcarbodiimide Purity >99.0% (GC) I-Peptide Coupling Reagent Factory

Inkcazelo emfutshane:

Igama leMchiza: N,N'-Dicyclohexylcarbodiimide

Izithethantonye: DCC

CAS: 538-75-0

Imbonakalo: Ikristale eMhlophe okanye uLwelo oluMthubi oKhanyayo

Ubunyulu: >99.0% (GC)

Peptide Coupling Reagents, umgangatho ophezulu

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 

 


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-N, N'-Dicyclohexylcarbodiimide (DCC) (CAS: 538-75-0) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-reagents ezikhuselayo kunye ne-coupling reagents.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iDCC,Please contact: alvin@ruifuchem.com 

Iipropati zeMichiza:

Igama leMchiza N,N'-Dicyclohexylcarbodiimide
Izithethantonye iDCC;Dicyclohexylcarbodiimide
Inombolo yeCAS 538-75-0
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C13H22N2
Ubunzima beMolekyuli 206.33
Indawo yokunyibilika 32.0 ~ 36.0℃
Indawo yokubilisa 122.0~124.0℃/6 mm Hg(lit.)
Ukuxinana 1.247 g/mL ku-25℃
Inovakalelo Ukungenwa kukufuma
Ukunyibilika emanzini Ayinyibilikiyo emanzini
Ukunyibilika Inyibilika kwiMethanol
Ugcino Temp. Indawo epholileyo neyomileyo (2~8℃)
I-COA kunye ne-MSDS Iyafumaneka
Udidi Coupling Reagents
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Ikristale emhlophe okanye uLwelo oluMthubi oluKhanyayo
Ubunyulu / Indlela yokuHlalutya >99.0% (GC)
Indawo yokunyibilika 32.0℃~36.0℃
Ilahleko ekomisweni <0.50%
Uvavanyo lwesisombululo (kwiAcetone) Icacile kwaye icace
Umba onganyibilikiyo kwi-acetone Akukho nanye
Ukungcola ngokupheleleyo <1.00%
Ugcino Khusela ukukhanya kwaye ugcine kwindawo epholileyo neyomileyo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Peptide Coupling Reagents

Ukupakishwa kunye noGcino:

Umqulu:Ibhotile, 25kg / Drum, okanye ngokwemfuno umthengi.
Imeko yoGcino:Ukufuma Kungevani, gcina kude namanzi/ukufuma.Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Indlela yoHlahlelo:

1 Injongo
Cacisa inkqubo yokuhlolwa kweDCC.
2 Uluhlu
Isebenza kuhlolo lwe-DCC kwinkampani yaseRuifu.
3 Isiseko
I-Chinese Pharmacopoeia 2005 edition, umgangatho wolawulo lwangaphakathi lweshishini.
4. Uxanduva
4.1 ISebe leMigangatho linoxanduva lokuqeqesha nokukhokela.
4.2 Umhlalutyi uya kuba noxanduva lomsebenzi othile kunye nokuchaneka kweziphumo zovavanyo.
Iinkqubo zokuSebenza ezi-5
5.1 Iimpawu: Le mveliso yikristale emhlophe okanye ulwelo olumthubi olukhanyayo.
Thatha i-100 grams yesampuli kwaye uyibeke kwi-beaker, uyipholise kwiqondo lomkhenkce, kwaye uyifudumeze ukuze inyibilike.Jonga umbala kunye nekristale ngokwahlukileyo
5.2 Indawo yokukhenkca
Beka isampuli ye-15ml kwi-tube yokuvavanya ye-20ml.Isampulu inyibilike ngokupheleleyo xa ishushu kwi-45℃.Dlulisa ityhubhu yovavanyo kwibhafu yamanzi kwi-25 ℃
Ngaphakathi, xuba kwaye ufake isitywina se-thermometer.Rhoqo ngemizuzwana engama-30 de ulwelo luqine, emva koko yonke imizuzwana eyi-15,
Iqondo lokushisa elibonisiweyo yindawo yokukhenkceza de i-thermometer ihlale ingatshintshi malunga ne-1min.
5.3 Ukumiselwa komxholo
Ukuzimisela nge-chromatography yegesi (Isihlomelo se-Chinese Pharmacopoeia 2005 Edition).
Isixhobo: Kexiao GC1690 igesi ikholamu yeChromatograph: ATSE-54
Ubushushu bekholamu: 230℃ Irhasi yokuthwala: initrogen
Ubushushu bokubona: 300℃ Iqondo lobushushu lokutofa: 280℃
Shunt ratio: 50:1 Detector: FID
Faka i-0.2ul yesisombululo sovavanyo kwi-chromatograph ye-15 min.Ilinganiswe ngendlela yokulinganisa indawo.
5.4 Iziphumo
Ibalwe ngendlela yesiqhelo yendawo, iDCC ayisayi kuba ngaphantsi kwe 99.0%.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

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538-75-0 - Umngcipheko kunye noKhuseleko:

Iikhowudi zoMngcipheko
I-R23/24/25 - Ityhefu ngokuphefumla, xa udibana nesikhumba kwaye xa uginyiwe.
I-R34 - Ibangela ukutsha
R40 - Ubungqina obuncinci besiphumo somhlaza
I-R43 - Inokubangela uvakalelo ngokudibana nolusu
R41 - Umngcipheko womonakalo omkhulu emehlweni
R36/38 - Iyacaphukisa emehlweni kunye nolusu.
I-R21 - Iyingozi xa udibana nolusu
R24 - Ityhefu xa udibana nolusu
I-R22 - Iyingozi xa iginyiwe
I-R62 - Umngcipheko onokubakho wokuphazamiseka kokuchuma
I-R37/38 - Iyacaphukisa inkqubo yokuphefumla kunye nolusu.
I-R10 -Inokutsha
I-R61 - Inokubangela ingozi kumntwana ongekazalwa
I-R26 - Ityhefu kakhulu ngokuphefumla
I-R38 - Iyacaphukisa ulusu
I-R20/22 - Inobungozi ngokuphefumlelwa kwaye ukuba iginywe.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
S41 - Kwimeko yomlilo kunye / okanye ugqabhuko-dubulo musa ukuphefumla umsi.
S24 - Kuphephe ukudibana nolusu.
I-S37/39 - Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
S16 - Gcina kude kwimithombo yomlilo.
S53-Kuphephe ukuvezwa-fumana imiyalelo ekhethekileyo phambi kokusetyenziswa.
S28 - Emva kokudibana nolusu, hlamba ngoko nangoko ngeesepha ezininzi.
Ii-ID ze-UN UN 2922 8/PG 2
WGK eJamani 3
RTECS FF2160000
FLUKA BRAND F IIKHOWUDI 3-8-10-21
TSCA Ewe
Ikhowudi yeHS 2925290090
Udidi lweengozi 6.1
Ukupakisha Iqela II
Ubuthi LD50 ngomlomo kuMvundla: 1110 mg/kg LD50 impuku yedermal 71 mg/kg

Isicelo:

I-DCC (N, N'-Dicyclohexylcarbodiimide, CAS: 538-75-0) isetyenziswe kwi-peptide chemistry njenge-reagent yokudibanisa.Isetyenziswa kakhulu kwi-artificial synthesis yeepeptides Ukujiya kwee-amino acids.Ngokomzekelo, kwi-Fmoc-solid phase synthesis, iqela le-carboxyl le-amino acid lenza i-amide bond kunye neqela le-amino lenye i-amino acid.Ukuze wenze iqela le-carboxyl likwamkele ngakumbi ukuhlaselwa kwe-nucleophiles, i-athomu ye-oksijini ehlawuliswa kakubi kufuneka isebenze kwiqela elihamba kakuhle, kwaye i-DCC idlala le ndima.I-athomu ye-oksijini yeqela le-carboxyl kwi-amino acid isebenza njenge-nucleophile ukuhlasela i-athomu ye-carbon embindini we-molecule ye-DCC ukuze i-DCC idibanise neqela le-carboxyl ukwenza isakhiwo se-ester, okwenza uhlaselo lwe-nucleophilic lweqela le-amino. kulula ukwenza i-coupling reagent.

I-DCC isetyenziselwa ukudibanisa kunye nokuchithwa kwe-amikacin kunye ne-amino acids.yinto efanelekileyo ephantsi yobushushu be-biochemical dehydrating agent kwaye isetyenziselwa ukuhlanganiswa kwe-acids, i-anhydrides, i-aldehydes, i-ketones, njl njl. EJapan, i-dehydrating agents ezisetyenziselwa i-akhawunti ye-glutathione kwi-90% yokusetyenziswa ngokupheleleyo.Xa imveliso isetyenziswe njenge-dehydration kunye ne-condensing agent, inokuphendulwa ngexesha elifutshane kwiqondo lokushisa, kwaye imveliso emva kokusabela yi-dicyclohexylurea.Ekubeni i-solubility yemveliso kwi-solvent ye-organic incinci kakhulu, imveliso yokusabela kulula ukwahlula;ngelo xesha, ngenxa yokuba imveliso inzima ukunyibilika emanzini, ukusabela kusenokuqhubeka nakwisisombululo esinamanzi.Imveliso isetyenziselwa ukuhlanganiswa kweepeptides kunye ne-nucleic acids.Ukusetyenziswa kwale mveliso kunokwenza ngokulula i-peptides kwiikhompawundi kunye namaqela e-carboxyl yamahhala kunye neekhompawundi kunye namaqela e-amino amahhala kwiqondo lokushisa, kwaye isivuno siphezulu kakhulu.Isetyenziselwa ukuveliswa kwe-hypertensives kunye ne-cyclic adenosine monophosphate.isetyenziswe njenge-biochemical reagent kunye ne-organic synthesis dehydration condensing agent.

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