I-DCC CAS 538-75-0 Dicyclohexylcarbodiimide Purity >99.0% (GC) I-Peptide Coupling Reagent Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-N, N'-Dicyclohexylcarbodiimide (DCC) (CAS: 538-75-0) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-reagents ezikhuselayo kunye ne-coupling reagents.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga iDCC,Please contact: alvin@ruifuchem.com
Igama leMchiza | N,N'-Dicyclohexylcarbodiimide |
Izithethantonye | iDCC;Dicyclohexylcarbodiimide |
Inombolo yeCAS | 538-75-0 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C13H22N2 |
Ubunzima beMolekyuli | 206.33 |
Indawo yokunyibilika | 32.0 ~ 36.0℃ |
Indawo yokubilisa | 122.0~124.0℃/6 mm Hg(lit.) |
Ukuxinana | 1.247 g/mL ku-25℃ |
Inovakalelo | Ukungenwa kukufuma |
Ukunyibilika emanzini | Ayinyibilikiyo emanzini |
Ukunyibilika | Inyibilika kwiMethanol |
Ugcino Temp. | Indawo epholileyo neyomileyo (2~8℃) |
I-COA kunye ne-MSDS | Iyafumaneka |
Udidi | Coupling Reagents |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ikristale emhlophe okanye uLwelo oluMthubi oluKhanyayo |
Ubunyulu / Indlela yokuHlalutya | >99.0% (GC) |
Indawo yokunyibilika | 32.0℃~36.0℃ |
Ilahleko ekomisweni | <0.50% |
Uvavanyo lwesisombululo (kwiAcetone) | Icacile kwaye icace |
Umba onganyibilikiyo kwi-acetone | Akukho nanye |
Ukungcola ngokupheleleyo | <1.00% |
Ugcino | Khusela ukukhanya kwaye ugcine kwindawo epholileyo neyomileyo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Peptide Coupling Reagents |
Umqulu:Ibhotile, 25kg / Drum, okanye ngokwemfuno umthengi.
Imeko yoGcino:Ukufuma Kungevani, gcina kude namanzi/ukufuma.Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
1 Injongo
Cacisa inkqubo yokuhlolwa kweDCC.
2 Uluhlu
Isebenza kuhlolo lwe-DCC kwinkampani yaseRuifu.
3 Isiseko
I-Chinese Pharmacopoeia 2005 edition, umgangatho wolawulo lwangaphakathi lweshishini.
4. Uxanduva
4.1 ISebe leMigangatho linoxanduva lokuqeqesha nokukhokela.
4.2 Umhlalutyi uya kuba noxanduva lomsebenzi othile kunye nokuchaneka kweziphumo zovavanyo.
Iinkqubo zokuSebenza ezi-5
5.1 Iimpawu: Le mveliso yikristale emhlophe okanye ulwelo olumthubi olukhanyayo.
Thatha i-100 grams yesampuli kwaye uyibeke kwi-beaker, uyipholise kwiqondo lomkhenkce, kwaye uyifudumeze ukuze inyibilike.Jonga umbala kunye nekristale ngokwahlukileyo
5.2 Indawo yokukhenkca
Beka isampuli ye-15ml kwi-tube yokuvavanya ye-20ml.Isampulu inyibilike ngokupheleleyo xa ishushu kwi-45℃.Dlulisa ityhubhu yovavanyo kwibhafu yamanzi kwi-25 ℃
Ngaphakathi, xuba kwaye ufake isitywina se-thermometer.Rhoqo ngemizuzwana engama-30 de ulwelo luqine, emva koko yonke imizuzwana eyi-15,
Iqondo lokushisa elibonisiweyo yindawo yokukhenkceza de i-thermometer ihlale ingatshintshi malunga ne-1min.
5.3 Ukumiselwa komxholo
Ukuzimisela nge-chromatography yegesi (Isihlomelo se-Chinese Pharmacopoeia 2005 Edition).
Isixhobo: Kexiao GC1690 igesi ikholamu yeChromatograph: ATSE-54
Ubushushu bekholamu: 230℃ Irhasi yokuthwala: initrogen
Ubushushu bokubona: 300℃ Iqondo lobushushu lokutofa: 280℃
Shunt ratio: 50:1 Detector: FID
Faka i-0.2ul yesisombululo sovavanyo kwi-chromatograph ye-15 min.Ilinganiswe ngendlela yokulinganisa indawo.
5.4 Iziphumo
Ibalwe ngendlela yesiqhelo yendawo, iDCC ayisayi kuba ngaphantsi kwe 99.0%.
Iikhowudi zoMngcipheko
I-R23/24/25 - Ityhefu ngokuphefumla, xa udibana nesikhumba kwaye xa uginyiwe.
I-R34 - Ibangela ukutsha
R40 - Ubungqina obuncinci besiphumo somhlaza
I-R43 - Inokubangela uvakalelo ngokudibana nolusu
R41 - Umngcipheko womonakalo omkhulu emehlweni
R36/38 - Iyacaphukisa emehlweni kunye nolusu.
I-R21 - Iyingozi xa udibana nolusu
R24 - Ityhefu xa udibana nolusu
I-R22 - Iyingozi xa iginyiwe
I-R62 - Umngcipheko onokubakho wokuphazamiseka kokuchuma
I-R37/38 - Iyacaphukisa inkqubo yokuphefumla kunye nolusu.
I-R10 -Inokutsha
I-R61 - Inokubangela ingozi kumntwana ongekazalwa
I-R26 - Ityhefu kakhulu ngokuphefumla
I-R38 - Iyacaphukisa ulusu
I-R20/22 - Inobungozi ngokuphefumlelwa kwaye ukuba iginywe.
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
S41 - Kwimeko yomlilo kunye / okanye ugqabhuko-dubulo musa ukuphefumla umsi.
S24 - Kuphephe ukudibana nolusu.
I-S37/39 - Nxiba iiglavu ezifanelekileyo kunye nokukhusela amehlo / ubuso
I-S24/25 - Gwema ukudibana nolusu kunye namehlo.
S36 - Nxiba iimpahla ezifanelekileyo zokukhusela.
S16 - Gcina kude kwimithombo yomlilo.
S53-Kuphephe ukuvezwa-fumana imiyalelo ekhethekileyo phambi kokusetyenziswa.
S28 - Emva kokudibana nolusu, hlamba ngoko nangoko ngeesepha ezininzi.
Ii-ID ze-UN UN 2922 8/PG 2
WGK eJamani 3
RTECS FF2160000
FLUKA BRAND F IIKHOWUDI 3-8-10-21
TSCA Ewe
Ikhowudi yeHS 2925290090
Udidi lweengozi 6.1
Ukupakisha Iqela II
Ubuthi LD50 ngomlomo kuMvundla: 1110 mg/kg LD50 impuku yedermal 71 mg/kg
I-DCC (N, N'-Dicyclohexylcarbodiimide, CAS: 538-75-0) isetyenziswe kwi-peptide chemistry njenge-reagent yokudibanisa.Isetyenziswa kakhulu kwi-artificial synthesis yeepeptides Ukujiya kwee-amino acids.Ngokomzekelo, kwi-Fmoc-solid phase synthesis, iqela le-carboxyl le-amino acid lenza i-amide bond kunye neqela le-amino lenye i-amino acid.Ukuze wenze iqela le-carboxyl likwamkele ngakumbi ukuhlaselwa kwe-nucleophiles, i-athomu ye-oksijini ehlawuliswa kakubi kufuneka isebenze kwiqela elihamba kakuhle, kwaye i-DCC idlala le ndima.I-athomu ye-oksijini yeqela le-carboxyl kwi-amino acid isebenza njenge-nucleophile ukuhlasela i-athomu ye-carbon embindini we-molecule ye-DCC ukuze i-DCC idibanise neqela le-carboxyl ukwenza isakhiwo se-ester, okwenza uhlaselo lwe-nucleophilic lweqela le-amino. kulula ukwenza i-coupling reagent.
I-DCC isetyenziselwa ukudibanisa kunye nokuchithwa kwe-amikacin kunye ne-amino acids.yinto efanelekileyo ephantsi yobushushu be-biochemical dehydrating agent kwaye isetyenziselwa ukuhlanganiswa kwe-acids, i-anhydrides, i-aldehydes, i-ketones, njl njl. EJapan, i-dehydrating agents ezisetyenziselwa i-akhawunti ye-glutathione kwi-90% yokusetyenziswa ngokupheleleyo.Xa imveliso isetyenziswe njenge-dehydration kunye ne-condensing agent, inokuphendulwa ngexesha elifutshane kwiqondo lokushisa, kwaye imveliso emva kokusabela yi-dicyclohexylurea.Ekubeni i-solubility yemveliso kwi-solvent ye-organic incinci kakhulu, imveliso yokusabela kulula ukwahlula;ngelo xesha, ngenxa yokuba imveliso inzima ukunyibilika emanzini, ukusabela kusenokuqhubeka nakwisisombululo esinamanzi.Imveliso isetyenziselwa ukuhlanganiswa kweepeptides kunye ne-nucleic acids.Ukusetyenziswa kwale mveliso kunokwenza ngokulula i-peptides kwiikhompawundi kunye namaqela e-carboxyl yamahhala kunye neekhompawundi kunye namaqela e-amino amahhala kwiqondo lokushisa, kwaye isivuno siphezulu kakhulu.Isetyenziselwa ukuveliswa kwe-hypertensives kunye ne-cyclic adenosine monophosphate.isetyenziswe njenge-biochemical reagent kunye ne-organic synthesis dehydration condensing agent.