I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5 Ubunyulu > 98.0% (HPLC)
UMvelisi oPhambili kunye noMboneleli
Abaphakathi kweRamelteon:
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-enye CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
Igama leMchiza | (S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride |
Izithethantonye | I-Despropionyl Ramelteon Hydrochloride;(S) -2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride;(S)-2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine HCl;Ukungcola kweRamelteon 15 HCl;Ramelteon Amine Ukungcola |
Inombolo yeCAS | 196597-80-5 |
Inombolo yeCAT | RF2888 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C13H17NO.HCl |
Ubunzima beMolekyuli | 239.74 |
Indawo yokunyibilika | 270℃ |
Ukunyibilika emanzini | Inyibilika kwiChloroform, Dichloromethane, Ethyl Acetate, Methanol |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oqinileyo oMhlophe ukuya koMhlophe |
Ubunyulu / Indlela yokuHlalutya | >98.0% (HPLC) |
Ilahleko ekomisweni | <1.00% |
Ukungacoceki Okukodwa | <1.00% |
Ukungcola ngokupheleleyo | <2.00% |
I-1 H NMR Spectrum | Ukungqinelana Nolwakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi weRamelteon (CAS: 196597-26-9) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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(S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl) ethylamine Hydrochloride, eyaziwa ngokuba yiDespropionyl Ramelteon Hydrochloride (CAS: 196597-80-5) ) yindawo ephakathi kweRamelteon (CAS: 196597-26-9).I-Ramelteon (TAK-375) iyinoveli ye-melatonin receptor agonist ye-MT1 yabantu kunye ne-MT2 receptors kunye ne-chick forebrain melatonin receptors kunye ne-Ki ye-14 pM, i-112 pM kunye ne-23.1 pM, ngokulandelanayo.Imolekyuli ye-melatonin yatshintshwa ikakhulu ngokutshintsha initrogen yeringi ye-indole ngekhabhoni ukunika iringi ye-indane kunye nokubandakanya iqela le-5-methoxyl kwiringi ye-indole kwiringi ye-furan eyomeleleyo.Ukukhethwa kwesiphumo se-Ramelteon ye-MT1 receptor ngamaxesha asibhozo ngaphezu kwe-MT2 receptor.Ngokungafaniyo ne-melatonin, isebenza ngakumbi ekuqaliseni ukulala (umsebenzi we-MT1) kunokuba ulungise isigqi se-circadian (umsebenzi we-MT2).Kubonakala ngathi isebenza ngokucace ngakumbi kune-melatonin kodwa ingasebenzi kakuhle kune-benzodiazepines njenge-hypnotic.Okubalulekileyo, eli chiza alinatyala lokulutha (ayisiyonto ilawulwayo).Ngenxa yoko, isanda kuvunywa kunyango lokungalali.