Desquinolinyl Lenvatinib CAS 796848-79-8 Ubunyulu >99.0% (HPLC) Lenvatinib Mesylate Intermediate Factory

Inkcazelo emfutshane:

1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea

Izithethantonye: Desquinolinyl Lenvatinib

I-CAS: 796848-79-8

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Okumhlophe-kuMhlophe ukuya kuBomvu oBrown obuqinileyo obuqinileyo

Umbindi weLenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Lenvatinib Mesylate Intermediate with High Purity
Lenvatinib Mesylate CAS 857890-39-2
I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
I-Desquinolinyl Lenvatinib;I-1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
I-4-Amino-3-Chlorophenol CAS 17609-80-2
I-4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Iipropati zeMichiza:

Igama leMchiza	1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea
Izithethantonye	I-Desquinolinyl Lenvatinib;Ukungcola kweLenvatinib 16;Ukungcola kweLenvatinib Desquinolinyl;Ukungcola kweLenvatinib LFS-A;ILenvatinib Mesylate ePhakathi Ⅲ;N-(2-Chloro-4-Hydroxyphenyl)-N'-Cyclopropyl-Urea
Inombolo yeCAS	796848-79-8
Inombolo yeCAT	RF-PI1972
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C10H11ClN2O2
Ubunzima beMolekyuli	226.66
Indawo yokubilisa	364.6±42.0℃
Ukuxinana	1.43±0.10 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-Off-White ukuya kuBomvu obumdaka obumdaka obuqinileyo
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Ukufuma (KF)	<0.50%
Intsalela kwi-Ignition	<0.20%
Ukungacoceki Okukodwa	<0.50%
Ukungcola ngokupheleleyo	<1.00%
Iintsimbi ezinzima	<10ppm
I-Infrared Spectrum	Iyahambelana noLwakhiwo
NMR	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weLenvatinib Mesylate (CAS: 857890-39-2)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-1-(2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea, eyaziwa nangokuthi i-Desquinolinyl Lenvatinib, (i-CAS: 796848-79-8) iphakathi okanye ukungcola kweLenvatinib Mesylate (CAS: 857890-39-2).I-Desquinolinyl Lenvatinib yi-metabolite ye-Lenvatinib Mesylate eyi-inhibitor esebenzayo yomlomo ye-multiple receptor tyrosine kinases kuquka i-VEGF, i-FGF kunye ne-SCF receptors.I-Lenvatinib lichiza elichasayo lomhlaza kunyango lweentlobo ezithile zomhlaza wegilo, kwaye kunokwenzeka nakwezinye ii-cancer.Ngomhla we-13 kaFebruwari, i-2015, i-US FDA ivume i-anticancer drug Lenvatinib kunyango lomhlaza we-thyroid.I-Lenvatinib yi-inhibitor ye-enzyme ejoliswe kwizinto ezininzi, ekwazi ukuthintela i-VEGFR2 kunye ne-VEGFR3 (i-vascular endothelial growth factor receptor).Igama lezorhwebo leLenvatinib yiLenvima.