I-Diethyl(3-pyridyl)borane CAS 89878-14-8 Ubunyulu>99.0% (HPLC) I-Abiraterone Acetate Intermediate Factory
Ubonelelo lwabavelisi, ubunyulu obuphezulu, iMveliso yoRhwebo
Igama leKhemikhali: Diethyl(3-pyridyl)borane
CAS: 89878-14-8
| Igama leMchiza | I-Diethyl(3-pyridyl)borane |
| Izithethantonye | 3-(Diethylboryl)pyridine |
| Inombolo yeCAS | 89878-14-8 |
| Inombolo yeCAT | RF-PI674 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C9H14BN |
| Ubunzima beMolekyuli | 147.03 |
| Indawo yokunyibilika | 159.0~164.0℃ (Isibane.) |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo oMhlophe |
| I-Infrared Spectrum | Iyahambelana noLwakhiwo |
| Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
| Ilahleko ekomisweni | ≤0.50% |
| Intsalela kwi-Ignition | ≤0.50% |
| Ukungacoceki Okukodwa | ≤0.50% |
| Ukungcola ngokupheleleyo | <1.00% |
| Iintsimbi ezinzima (njenge Pb) | ≤20ppm |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | Umbindi we-Abiraterone Acetate (CAS: 154229-18-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-Diethyl (3-pyridyl) i-borane (i-CAS: 89878-14-8) yindawo ephakathi ye-Abiraterone Acetate (CAS: 154229-18-2).Ngo-Aprili 2011, i-United States FDA yavuma i-Abiraterone Acetate ngokudibanisa ne-steroid prednisone yonyango lwe-metastatic castration-resistant prostate cancer (mCRPC) kwizigulane ezazinyangwa ngaphambili nge-docetaxel equlethe irejimeni yesifo sesigaba sasemva kwexesha.Ichiza, elithengiswe phantsi kwegama lokurhweba uZytiga, ekuqaleni lafunyanwa ngabaphandi kwiCancer Research UK Centre yeCancer Therapeutics ngo-1990, yaphuhliswa yiCougar Biotechnology, kwaye ekugqibeleni yathengiswa nguJohnson & Johnson emva kokufunyanwa kwayo kweCougar ngo-2009.
