I-Diethyl(3-pyridyl)borane CAS 89878-14-8 Ubunyulu>99.0% (HPLC) I-Abiraterone Acetate Intermediate Factory
Ubonelelo lwabavelisi, ubunyulu obuphezulu, iMveliso yoRhwebo
Igama leKhemikhali: Diethyl(3-pyridyl)borane
CAS: 89878-14-8
Igama leMchiza | I-Diethyl(3-pyridyl)borane |
Izithethantonye | 3-(Diethylboryl)pyridine |
Inombolo yeCAS | 89878-14-8 |
Inombolo yeCAT | RF-PI674 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C9H14BN |
Ubunzima beMolekyuli | 147.03 |
Indawo yokunyibilika | 159.0~164.0℃ (Isibane.) |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe |
I-Infrared Spectrum | Iyahambelana noLwakhiwo |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.50% |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | <1.00% |
Iintsimbi ezinzima (njenge Pb) | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi we-Abiraterone Acetate (CAS: 154229-18-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
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I-Diethyl (3-pyridyl) i-borane (i-CAS: 89878-14-8) yindawo ephakathi ye-Abiraterone Acetate (CAS: 154229-18-2).Ngo-Aprili 2011, i-United States FDA yavuma i-Abiraterone Acetate ngokudibanisa ne-steroid prednisone yonyango lwe-metastatic castration-resistant prostate cancer (mCRPC) kwizigulane ezazinyangwa ngaphambili nge-docetaxel equlethe irejimeni yesifo sesigaba sasemva kwexesha.Ichiza, elithengiswe phantsi kwegama lokurhweba uZytiga, ekuqaleni lafunyanwa ngabaphandi kwiCancer Research UK Centre yeCancer Therapeutics ngo-1990, yaphuhliswa yiCougar Biotechnology, kwaye ekugqibeleni yathengiswa nguJohnson & Johnson emva kokufunyanwa kwayo kweCougar ngo-2009.