I-Diethylphosphonoacetic Acid CAS 3095-95-2 Ubunyulu >99.5% (HPLC) I-Afatinib Dimaleate Intermediate Factory
I-Ruifu Chemical Supply Intermediates ye-Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)i-acetaldehyde I-Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
I-Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H)-enye CAS 162012-69-3
I-7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineI-CAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineI-CAS 314771-88-5
Igama leMchiza | I-Diethylphosphonoacetic Acid |
Izithethantonye | I-2-(Diethoxyphosphoryl)i-acetic Acid;(Diethoxyphosphinyl)iAcetic Acid;I-Diethyl Carboxymethylphosphonate;NSC 272281 |
Inombolo yeCAS | 3095-95-2 |
Inombolo yeCAT | RF-PI2024 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ye-30MT / ngenyanga |
Ifomula yeemolekyuli | (C2H5O)2P(O)CH2CO2H |
Ubunzima beMolekyuli | 196.14 |
Indawo yokubilisa | 150℃/0.05 mmHg (lit.) |
Ukuxinana | 1.220 g/mL ku-25℃ (lit.) |
Refractive Index | n20/D 1.445 (lit.) |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ulwelo olungenambala |
Ukuchongwa (HPLC) | Ixesha lokugcinwa kwencopho ephambili efunyenwe kwisampulu ingaphakathi kwe-5% yesampulu yereferensi. |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Proton NMR Spectrum | Iyahambelana neSakhiwo |
Ukufuma (KF) | <0.50% |
Ukungcola ngokupheleleyo | <0.50% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kwe-Afatinib Dimaleate (CAS: 850140-73-7) |
Iphakheji: Ibhotile eFluorinated, 25kg/ Igubu, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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I-Diethylphosphonoacetic Acid (CAS: 3095-95-2), Isebenza njenge-nucleophile ye-nucleophilic reaction reactions for synthesis of allene epoxides I-Reactant for: Izifundo ze-Stereoselectivity ze-Staudinger reaction;Ukwenziwa kwe-Enantioselective yee-diols nge-epoxidation kunye ne-hydration reactions;Horner-Wadsworth-Emmons iimpendulo;Remote chelation controlled Ireland-Claisen rearrangement;Ugi-Dieckmann reactions for synthesis of tetramic acid derivatives;Isetyenziselwa ukwenza i-phosphonoester intermediates kwi-intramolecular HEW reactions.I-Diethylphosphonoacetic Acid iphakathi kwe-Afatinib Dimaleate (CAS: 850140-73-7).I-Afatinib Dimaleate yavunywa yi-US Food and Drug Administration (FDA) kwi-2013 yonyango lwe-non-small cell lung cancer (NSCLC).Ngokukodwa, yamkelwa kwizigulana ezibonisa i-metastatic NSCLC tumors equlathe ukucinywa kwe-epidermal growth factor receptor (EGFR) okanye ukuguqulwa kwe-exon 21.I-Afatinib Dimaleate yi-covalent inhibitor ye-ErbB tyrosine kinases (tyk), eyehlisa umqondiso we-ErbB ngokubophelela ngokungenakuguquleka kweendawo ezibophelelayo ze-EGFR tyk.
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I-Diethylphosphonoacetic Acid CAS 3095-95-2 Purit...
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(Dimethylamino)acetaldehyde Diethyl Acetal CAS ...
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(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2...
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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroqui...
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Trans-4-Dimethylaminocrotonic Acid Hydrochlorid...
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I-7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449...
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7-Fluoro-6-Nitroquinazolin-4 (1H)-enye CAS 162012...
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Afatinib Dimaleate Intermediate CAS 314771-88-5...
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Afatinib Dimaleate Intermediate CAS 314771-76-1...
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Afatinib Dimaleate CAS 850140-73-7 Ubunyulu > 99.5...