(Dimethylamino)i-acetaldehyde i-Diethyl Acetal CAS 3616-56-6 Ubunyulu>99.0% (GC) I-Afatinib Dimaleate Intermediate Factory

Inkcazelo emfutshane:

Igama: (Dimethylamino)acetaldehyde Diethyl Acetal

Izithethantonye: 2,2-Diethoxy-N,N-Dimethylethylamine

CAS: 3616-56-6

Ubunyulu: >99.0% (GC)

Imbonakalo: Ulwelo olungenambala olucacileyo

Phakathi kwe-Afatinib Dimaleate (CAS: 850140-73-7)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza (Dimethylamino) i-acetaldehyde i-Diethyl Acetal
Izithethantonye I-2,2-Diethoxy-N,N-Dimethylethylamine;N-(2,2-Diethoxyethyl)dimethylamine;2,2-Diethoxy-N,N-Dimethylethan-1-Amine
Inombolo yeCAS 3616-56-6
Inombolo yeCAT RF-PI2031
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C8H19NO2
Ubunzima beMolekyuli 161.25
Uvakalelo Ukungenwa kukufuma
Indawo yokubilisa 60℃/5 mmHg
Indawo yokuflasha 45℃
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Ulwelo olucacileyo olungenambala
Ubunyulu / Indlela yokuHlalutya >99.0% (GC)
Refractive Index N20/D 1.410~1.414
Ubunzima obuthile (20/20℃) 0.865~0,870
Proton NMR Spectrum Iyahambelana neSakhiwo
Ukungcola ngokupheleleyo <1.00%
Iintsimbi ezinzima (njenge Pb) ≤20ppm
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa abaPhakathi bamayeza;Afatinib Dimaleate;Sumatriptan

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile eneFluorinated, 25kg/Drum, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

1

FAQ:

Isicelo:

(I-Dimethylamino) i-acetaldehyde i-Diethyl Acetal (i-CAS: i-3616-56-6) isetyenziswe njenge-pharmaceutical intermediates.(I-Dimethylamino) i-acetaldehyde I-Diethyl Acetal ingasetyenziswa kwi-synthesis ye-Afatinib Dimaleate (CAS: 850140-73-7), i-Sumatriptan (CAS: 103628-46-2).I-Afatinib (igama lokurhweba i-Gilotrif e-US kunye ne-Giotrif eYurophu, eyayifudula iyi-Tomtovok ne-Tovok) lichiza elivunyiweyo e-United States, eYurophu, eTaiwan, e-Mexico, e-Chile nase-Japan kunye namanye amazwe kunyango lodidi lokuqala lwezigulana ezahlukileyo. iintlobo ze-metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), eyenziwe nguBoehringer Ingelheim.I-Afatinib isebenza njenge-covalent inhibitor engenakuguquleka ye-receptor tyrosine kinases ye-epidermal growth factor receptor (EGFR) kunye ne-erbB-2 (HER2).I-Sumatriptan yayiyi-triptan yokuqala evunyiweyo (1991) yonyango olunzima lwentloko ye-migraine.Ine-lowstoral bioavailability phakathi kwazo zonke iitriptans ngenxa ye-lowlipophilicity yayo.Ubukho beendlela ezininzi ezahlukeneyo zedosi (oko kukuthi, ithebhulethi yomlomo, inaliti ye-SC, ukubunjwa kwempumlo yokutshiza, kunye ne-suppository) ivumela ukuguquguquka konyango lokulungelelanisa kwiimfuno zesigulana ngasinye, ngaloo ndlela i-sumatriptans ibe lichiza eliluncedo kakhulu kunyango olunzima lwe-migraine. intloko ebuhlungu.I-Sumatriptan nayo ine-fastonset ekhawulezayo yesenzo ngenaliti ye-SC okanye ulawulo lokutshiza ngeempumlo.

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