(Dimethylamino)i-acetaldehyde i-Diethyl Acetal CAS 3616-56-6 Ubunyulu>99.0% (GC) I-Afatinib Dimaleate Intermediate Factory
I-Ruifu Chemical Supply Intermediates ye-Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)i-acetaldehyde I-Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
I-Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H)-enye CAS 162012-69-3
I-7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineI-CAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineI-CAS 314771-88-5
Igama leMchiza | (Dimethylamino) i-acetaldehyde i-Diethyl Acetal |
Izithethantonye | I-2,2-Diethoxy-N,N-Dimethylethylamine;N-(2,2-Diethoxyethyl)dimethylamine;2,2-Diethoxy-N,N-Dimethylethan-1-Amine |
Inombolo yeCAS | 3616-56-6 |
Inombolo yeCAT | RF-PI2031 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C8H19NO2 |
Ubunzima beMolekyuli | 161.25 |
Uvakalelo | Ukungenwa kukufuma |
Indawo yokubilisa | 60℃/5 mmHg |
Indawo yokuflasha | 45℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ulwelo olucacileyo olungenambala |
Ubunyulu / Indlela yokuHlalutya | >99.0% (GC) |
Refractive Index N20/D | 1.410~1.414 |
Ubunzima obuthile (20/20℃) | 0.865~0,870 |
Proton NMR Spectrum | Iyahambelana neSakhiwo |
Ukungcola ngokupheleleyo | <1.00% |
Iintsimbi ezinzima (njenge Pb) | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | abaPhakathi bamayeza;Afatinib Dimaleate;Sumatriptan |
Iphakheji: Ibhotile eneFluorinated, 25kg/Drum, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
(I-Dimethylamino) i-acetaldehyde i-Diethyl Acetal (i-CAS: i-3616-56-6) isetyenziswe njenge-pharmaceutical intermediates.(I-Dimethylamino) i-acetaldehyde I-Diethyl Acetal ingasetyenziswa kwi-synthesis ye-Afatinib Dimaleate (CAS: 850140-73-7), i-Sumatriptan (CAS: 103628-46-2).I-Afatinib (igama lokurhweba i-Gilotrif e-US kunye ne-Giotrif eYurophu, eyayifudula iyi-Tomtovok ne-Tovok) lichiza elivunyiweyo e-United States, eYurophu, eTaiwan, e-Mexico, e-Chile nase-Japan kunye namanye amazwe kunyango lodidi lokuqala lwezigulana ezahlukileyo. iintlobo ze-metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), eyenziwe nguBoehringer Ingelheim.I-Afatinib isebenza njenge-covalent inhibitor engenakuguquleka ye-receptor tyrosine kinases ye-epidermal growth factor receptor (EGFR) kunye ne-erbB-2 (HER2).I-Sumatriptan yayiyi-triptan yokuqala evunyiweyo (1991) yonyango olunzima lwentloko ye-migraine.Ine-lowstoral bioavailability phakathi kwazo zonke iitriptans ngenxa ye-lowlipophilicity yayo.Ubukho beendlela ezininzi ezahlukeneyo zedosi (oko kukuthi, ithebhulethi yomlomo, inaliti ye-SC, ukubunjwa kwempumlo yokutshiza, kunye ne-suppository) ivumela ukuguquguquka konyango lokulungelelanisa kwiimfuno zesigulana ngasinye, ngaloo ndlela i-sumatriptans ibe lichiza eliluncedo kakhulu kunyango olunzima lwe-migraine. intloko ebuhlungu.I-Sumatriptan nayo ine-fastonset ekhawulezayo yesenzo ngenaliti ye-SC okanye ulawulo lokutshiza ngeempumlo.