Docetaxel CAS 114977-28-5 Assay 98.0% ~ 102.0%
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili weDocetaxel (Taxotere) (CAS: 114977-28-5) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iDocetaxel,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Docetaxel |
| Izithethantonye | Taxotere;Taxotere Anhydrous;Docetaxel Anhydrous;I-N-Debenzoyl-N-tert-Butoxycarbonyl-10-Deacetyltaxol;RP-56976 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoRhwebo |
| Inombolo yeCAS | 114977-28-5 |
| Ifomula yeemolekyuli | C43H53NO14 |
| Ubunzima beMolekyuli | 807.89 g/mol |
| Indawo yokunyibilika | 186.0 ~ 192.0℃(dec.) |
| Ukuxinana | 1.38 |
| Ukunyibilika | Inyibilika kakhulu kwi-acetone, iDimethylformamide.Inyibilika kwi-Ethanol, iDichloromethane, iMethanol.Ayinyibilikiyo emanzini |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo weCrystalline oMhlophe | Umgubo weCrystalline oMhlophe |
| Ukuchongwa | I-IR & HPLC | Iyahambelana |
| Ujikelezo oluKhethekileyo [a]20/D | -42.0 ° ukuya -45.0 ° (C=1 kwi-EtOH) | -43.1 ° |
| Ilahleko ekomisweni | <3.00% | 2.05% |
| Intsalela kwi-Ignition | <0.10% | 0.04% |
| Iintsimbi ezinzima (Pb) | ≤20ppm | <20ppm |
| IArsenic (As) | ≤1.5ppm | <1.5ppm |
| Izinto ezinxulumeneyo | ||
| Ukungacoceki okuphezulu okukodwa | <0.50% | <0.50% |
| Ukungcola ngokupheleleyo | <1.00% | <1.00% |
| Iimvavanyo zoMda weMicrobial | ||
| TAMC | ≤100cfu/g | <100cfu/g |
| I-TYMC | ≤10cfu/g | <10cfu/g |
| Iintsholongwane ze-Endotoxins | ≤0.3IU/mg | <0.3IU/mg |
| Indlela yoVavanyo / yoHlahlelo | 98.0%~102.0% (Kwisiseko seAnhydrous neSolvent-Free) | 100.9% |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Ugcino:Gcina isikhongozeli sivalwe ngokuqinileyo kwaye usigcine kwindawo epholileyo, eyomileyo (2~8℃) kunye nendawo yokugcina impahla engena moya ikude kwizinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iimpawu zeHazard Xi - Irritant
Iikhowudi zoMngcipheko
R36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumla kunye nolusu.
I-R61 - Inokubangela ingozi kumntwana ongekazalwa
Inkcazelo yoKhuseleko
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37 -Nxiba iimpahla ezifanelekileyo zokukhusela kunye neeglavu.
S53-Kuphephe ukuvezwa-fumana imiyalelo ekhethekileyo phambi kokusetyenziswa.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
Ii-ID ze-UN 1544
WGK eJamani 3
RTECS DA4172750
Ikhowudi yeHS 2932999029
Udidi lweeNgozi 6.1(b)
Ukupakisha Iqela III
Ubuthi LD50 emithanjeni inja: 2500ug/kg
I-Docetaxel (i-Taxotere) (i-CAS: i-114977-28-5) ithengiswa njenge-Taxotere okanye i-Docecad, i-anti-mitotic chemotherapy iyeza esekelwe kakuhle esebenza ngokuphazamisa ukuhlukana kweeseli.I-Docetaxel yamkelwe yi-FDA kunyango lomhlaza webele okwinqanaba eliphezulu okanye we-metastatic, umhlaza wentloko kunye nentamo, umhlaza wesisu, umhlaza wesifo se-hormone-refractory kunye nomhlaza wemiphunga ongeyiyo iseli encinci.I-Docetaxel ingasetyenziselwa njenge-arhente enye okanye ngokudibanisa namanye amachiza e-chemotherapeutic njengoko kubonisiwe kuxhomekeke kuhlobo oluthile lomhlaza kunye nesigaba.I-Docetaxel lilungu leklasi yeyeza le-taxane, elikwabandakanya amayeza e-chemotherapeutic paclitaxel.Nangona i-docetaxel ihlala inamandla ngokuphindwe kabini njenge-paclitaxel (ngenxa yempembelelo ye-docetaxel kwi-centrosome ye-mitotic spindle), ii-taxane ezimbini ziye zabonwa zisebenza ngokuthelekisayo.Amanqaku amaninzi akutshanje afumene "akukho bungqina bokuba iirejimeni eziqulethe i-docetaxel zinika inzuzo enkulu kunezo zibandakanya i-paclitaxel."Nangona ukusebenza kakuhle phakathi kwee-agent ezimbini kuye kwabonwa ukuba kuyalingana, i-paclitaxel inokubangela iziphumo ezibi ezimbalwa.Ukongeza, kuye kwaphawulwa ukuba i-docetaxel ithanda ukunganyangeki ngamachiza eselula ngeendlela ezahlukeneyo ezahlukeneyo.
1. I-Docetaxel liyeza elimiswe kakuhle ngokweklinikhi le-anti mitotic chemotherapy (oko kukuthi, liphazamisa ukwahlukana kweeseli).
2. I-Docetaxel isetyenziswa ikakhulu kunyango lwebele, i-ovarian, kunye nomhlaza wemiphunga yeseli engeyiyo encinci.
3. I-Docetaxel inebango elivunyiweyo le-FDA lonyango lwezigulane ezihambele phambili ekuhlaleni, okanye ibele le-metastatic okanye umhlaza wemiphunga ongeyiyo iseli encinci eye yafumana ichemotherapy esekelwe kwi-anthracycline kwaye ayikwazanga ukunqanda ukuqhubeka komhlaza okanye ubuyele kwakhona.Ukwamkelwa kwe-doce-taxel yaseYurophu ukuba isetyenziswe kumhlaza wedlala lesinyi.
4. I-Docetaxel ithathwa njengeyona nto ingcono, njenge-antimicrotubule ye-cytotoxic.
