I-Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory High Purity
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leKhemikhali: Doxorubicin Hydrochloride
CAS: 25316-40-9
Iarhente yeAntitumor Antibiotic.Inqanda i-DNA Topoisomerase II
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | Doxorubicin Hydrochloride |
Izithethantonye | Doxorubicin HCl;Adriamycin HCL;IHydroxydaunorubicin Hydrochloride |
Inombolo yeCAS | 25316-40-9 |
Inombolo yeCAT | RF-API38 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C27H30ClNO11 |
Ubunzima beMolekyuli | 579.98 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | I-Orenji-Ebomvu okanye i-Crystalline Powder ebomvu;Akukho bungqina bubonakalayo bokungcoliswa zizinto zangaphandle |
Ukunyibilika | Inyibilika emanzini nakwi-methanol;inyibilika kancinane kwi-ethanol;ayinyibiliki kwiacetone |
Isazisi A | I-spectrum ye-IR ihambelana ne-IR yomgangatho wereferensi |
Isazisi B | Ixesha lokugcinwa kwencopho ye-doxorubicin kwi-chromatogram yoLungiselelo lwe-Assay ihambelana naleyo kwi-chromatogram yoLungiselelo oluMgangatho, njengoko lufunyenwe kwi-Assay. |
pH | 4.0~5.5 |
Isiqulatho samanzi | ≤4.0% |
Izinto ezinxulumeneyo | |
Ukungcola A (Doxorubicinol) | ≤0.50% |
Nakuphi na Okunye Ukungcola Okungaziwayo | ≤0.20% |
Ukungcola Okungaziwa ngokupheleleyo | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Isivavanyi | I-98.0% ~ 102.0% ye-C27H30ClNO11 ibalwa kwisiseko se-anhydrous, i-solvent-free |
Izinyibilikisi ezishiyekileyo | |
I-acetone | ≤0.50% |
IAcetone + Ethanol | ≤2.5% |
IMethanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Umgangatho woVavanyo | I-United States Pharmacopeia (USP) iReference Standard |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Doxorubicin Hydrochloride (CAS: 25316-40-9) kunye nomgangatho ophezulu.I-Doxorubicin hydrochloride, i-cytotoxic anthracycline antibiotic, i-anti-cancer chemotherapy agent.I-Doxorubicin hydrochloride ngumntu onamandla we-DNA topoisomerase I kunye ne-topoisomerase II inhibitor ene-IC50s ye-0.8 μM kunye ne-2.67 μM, ngokulandelanayo.I-Doxorubicin hydrochloride yenza ukuba i-apoptosis kunye ne-autophagy.I-Doxorubicin sisixhobo esinamandla se-antitumour esisebenza ngokuchasene noluhlu olubanzi lwezifo ezinobungozi, kubandakanya i-leukemias, i-sarcomas, umhlaza wamabele, umhlaza wemiphunga omncinci kunye nomhlaza wesibeleko.