I-Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV

Inkcazelo emfutshane:

Igama: Entecavir

CAS: 142217-69-4

Imbonakalo: Umgubo weCrystalline oMhlophe

Iyeza elilwa nentsholongwane esetyenziswa kunyango lwe-Hepatitis B Usulelo

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leKhemikhali: Entecavir
CAS: 142217-69-4
Iyeza elilwa nentsholongwane esetyenziswa kunyango lwe-Hepatitis B Usulelo
Umgangatho ophezulu we-API, iMveliso yoRhwebo

Iipropati zeMichiza:

Igama leMchiza	Entecavir
Izithethantonye	I-2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-enye
Inombolo yeCAS	142217-69-4
Inombolo yeCAT	RF-API80
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	I-C12H15N5O3
Ubunzima beMolekyuli	277.28
Indawo yokunyibilika	249.0 ~ 252.0℃
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo weCrystalline oMhlophe
Ukuchongwa kwe-IR	I-spectrum yokufunxa i-infraed yesampuli yovavanyo kufuneka ihambelane nomgangatho wereferensi
Ukuchongwa kwe-HPLC	Ixesha lokugcinwa kwesampulu yovavanyo lihambelana nelo lomgangatho wereferensi
pH	5.5~7.5
Ujikelezo oluKhethekileyo lwe-Optical	+24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Izinto ezinxulumeneyo
Ukungcola ngokupheleleyo	≤0.30%
Ukungacoceki okuphezulu okukodwa	≤0.10%
I-Enantiomer	≤0.20%
Izinyibilikisi ezishiyekileyo
IMethanol	≤0.30%
Dichloromethane	≤0.06%
n-Hexane	≤0.029%
Tetrahydrofuran	≤0.072%
N, N-Dimethylformamide	≤0.088%
Toluene	≤0.089%
Isiqulatho samanzi	5.8%~6.5%
Intsalela kwi-Ignition	≤0.10%
Iintsimbi ezinzima	≤20ppm
Isivavanyi	98.0% ~ 102.0% (C12H15N5O3 ibalwa ngesiseko se-anhydrous)
Ubungakanani beNcam	D90: ≤100µm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	I-API, i-Antiviral drug esetyenziswa kunyango lwe-Hepatitis B Infection

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Entecavir isizukulwana esitsha se-guanine nucleoside analogues amayeza omlomo wonyango lwe-Hepatitis B Virus (HBV) usulelo, ngokukodwa kunyango lwezigulane zabantu abadala kunye nomsebenzi wokuphindaphinda kwentsholongwane kunye ne-serum transaminase yaqhubeka nokunyuka, okanye izicubu zesibindi ze-pathological activity of chronic hepatitis B. , okwangoku isezantsi intsholongwane ikhawuleza kakhulu kwaye inamandla, izinga lokuguquka kweyona nucleoside analogues.Idatha ibonisa ukuba ezahlukeneyo kwizigulane ezine-hepatitis B engapheliyo, kubandakanywa i-nucleoside naive kunye ne-nucleoside ephathwayo kunye nezigulane ze-cirrhosis yesibindi, ukusebenzisa iipilisi ze-entecavir kakuhle kunyango kunokulawula isifo ngokukhawuleza kwaye zifikeleleke ngokulula kunyango lwe-real end, i-virus ye-hepatitis B engenakulinganiswa;ngokubambelela kunyango, inxalenye enkulu yezigulane inokufikelelwa ekupheleni kolwaneliseko lonyango, oko kukuthi, ukuguqulwa kwe-antigen serology, ezinye izigulana zinokufikelela kunyango lwesiphelo, ezizezi, umphezulu we-antigen negative.