Epalrestat CAS 82159-09-9 Ubunyulu > 99.5% (HPLC) Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Epalrestat (CAS: 82159-09-9) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amancinci kunye nenani elikhulu elikhoyo.Thenga i-Epalrestat,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Epalrestat |
| Izithethantonye | Epalrest;I-ONO-2235;Ebeth;Kinedak;I-Sorbistat(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2-[(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E)-2-[5-(2-Methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMisa |
| Inombolo yeCAS | 82159-09-9 |
| Ifomula yeemolekyuli | I-C15H13NO3S2 |
| Ubunzima beMolekyuli | 319.39 g/mol |
| Indawo yokunyibilika | 222.0 ukuba 226.0℃ |
| Ukuxinana | 1.43±0.10 g/cm3 |
| Ukunyibilika | I-DMSO 2 mg/mL Amanzi <1 mg/mL I-Ethanol <1 mg/mL |
| Ugcino Temp. | Indawo epholileyo neyomileyo (-20℃) |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Udidi | API |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | IOrenji ukuya kwiOrenji eBomvu yeCrystalline Powder | Iyahambelana |
| Ukuchongwa | Ngokufana nexesha lokugcinwa kweHPLC elisemgangathweni | Dlula |
| Indawo yokunyibilika | 222.0 ukuba 226.0℃ | 222.4~224.3℃ |
| Ilahleko ekomisweni | <0.50% | 0.04% |
| Intsalela kwi-Ignition | <0.20% | 0.03% |
| Iintsimbi ezinzima (Pb) | ≤20ppm | <20ppm |
| Ukungcola ngokupheleleyo | ≤0.50% | 0.20% |
| Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) | 99.8% |
| I-Infrared Spectrum | Iyahambelana neSakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (-20℃) kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Ii-ID ze-UN 2811
WGK eJamani 3
RTECS XJ5131855
Udidi lweengozi 6.1
Ukupakisha Iqela II
I-Epalrestat (i-CAS: 82159-09-9) yi-inhibitor yesibini ye-aldose reductase eya kwaziswa kwihlabathi jikelele kwaye eyokuqala iqaliswe eJapan.I-Epalrestat iboniswa kunyango lwe-diabetes neuropathy.Ikwaphandwa nge-retinopathy yeswekile kunye ne-nephropathy.I-Epalrestat yi-aldose reductase inhibitor ene-IC50 ye-72 nM.
I-Epalrestat inqanda i-Aldose Reductase (AR) echaphazelekayo kwinqanaba lokunciphisa izinga lokuguqulwa kwe-glucose kwi-sorbitol phantsi kweemeko ze-hyperglycemic.I-Aldose reductase ibe yinto ekujoliswe kuyo yabaphandi abaninzi bekliniki ukunyanga isifo se-diabetes neuropathy kunye ne-retinopathy.I-Epalrestat lichiza elivunyiweyo eJapan naseIndiya, elisetyenziselwa unyango lwe-diabetes neuropathy.
I-Epalrestat isetyenziselwa ukuthintela, ukunciphisa, kunye nokunyanga i-peripheral neuropathy (i-numbness, intlungu), i-vibrational paresthesia, kunye nokungahambi kakuhle kwentliziyo ehambelana nesifo seswekile.
I-Epalrestat njengechiza elimeleli layo linciphisa ukuqokelelwa kwe-intracellular ye-fructose kunye ne-sorbitol ngokuthintela ngokubuyisela umsebenzi we-aldose reductase, ibuyisela i-Na+-K+-ATPase kunye nomsebenzi we-inositol, yonyusa AKUKHO kwakheka kwiiseli ze-endothelial, inhibits protein kinase C indlela yokubonisa, i-endothelial cell adhesion i-mediated neutrophil kunye ne-endothelial adhesion factor expression kunye nokunciphisa iimveliso ze-carboxymethyl lysine kwizigulana zeswekile, ngaloo ndlela kunyangwa izifo ezifana nesifo seswekile kunye neengxaki zaso.
